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[null,"1.","Record Nr.",null,"UNINA9910824844703321"]
[null,null,"Autore",null,"Clark William R. <1938->"]
[null,null,"Titolo",null,"A means to an end : the biological basis of aging and death / / William R. Clark"]
[null,null,"Pubbl/distr/stampa",null,"New York ; ; Oxford, [England] : , : Oxford University Press, , 1999"]
[{"$nulls":4},"©1999"]
[null,null,"ISBN",null,"0-19-770158-2"]
[{"$nulls":4},"1-280-50204-5"]
[{"$nulls":4},"9786610502042"]
[{"$nulls":4},"0-19-512593-2"]
[{"$nulls":4},"0-19-802911-X"]
[{"$nulls":4},"0-19-534839-7"]
[{"$nulls":4},"1-60256-775-1"]
[null,null,"Descrizione fisica",null,"1 online resource (252 p.)"]
[null,null,"Disciplina",null,"612.6/7"]
[null,null,"Soggetti",null,"Cells - Aging"]
[{"$nulls":4},"Apoptosis"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Originally published: 1999."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Contents; Acknowledgments; Introduction; 1. Aging, Senescence, and Lifespan; 2. The Nature of Cellular Senescence and Death; 3. The Evolution of Senescence and Death; 4. Of Embryos and Worms and Very Old Men: The Developmental Genetics of Senescence and Lifespan; 5. Human Genetic Diseases That Mimic the Aging Process; 6. Cycling to Senescence; 7. Replicative Immortality: Cancer and Aging; 8. Caloric Restriction and Maximum Lifespan; 9. With Every Breath We Take: Oxidative Stress and Cellular Senescence; 10. The Aging Brain; 11. A Conditional Benefit; Bibliography; Index"]
[null,null,null,"Sommario/riassunto","In this work, the various theories of ageing are explained and assessed. The author presents case accounts about disorders that open windows on to the ageing process. The impacts of ageing on the brain and nervous system are given special attention, as are the effects of caloric restriction on maximum lifespan."]