{"text_format":"2","workbook":"xls","n_sheets":1,"sheets":["report2"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":1,"defined_names":2,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"report2","index":0,"n_rows":57,"n_cols":5,"rows_kept":57,"cut":false,"hidden":false,"merged":[[0,2,0,3],[0,4,0,5],[1,2,1,3],[1,4,1,5],[2,2,2,3],[2,4,2,5],[3,2,3,3],[5,2,5,3],[8,2,8,3],[9,2,9,3],[10,2,10,3],[12,2,12,3],[13,2,13,3],[17,2,17,3],[25,2,25,3],[25,4,25,5],[26,2,26,3],[26,4,26,5],[27,2,27,3],[29,2,29,3],[37,2,37,3],[38,2,38,3],[39,2,39,3],[40,2,40,3],[44,2,44,3],[45,2,45,3],[49,2,49,3]],"flags":["formulas_cached_only"]}
[null,"1.","Record Nr.",null,"UNINA9910823412603321"]
[null,null,"Autore",null,"Kleinstreuer C"]
[null,null,"Titolo",null,"Microfluidics and nanofluidics : theory and selected applications / / Clement Kleinstreuer ; cover design Anne-Michele Abbott"]
[null,null,"Pubbl/distr/stampa",null,"Hoboken, New Jersey : , : Wiley, , 2014"]
[{"$nulls":4},"©2014"]
[null,null,"ISBN",null,"1-118-74989-8"]
[{"$nulls":4},"1-118-41800-X"]
[{"$nulls":4},"1-118-41527-2"]
[null,null,"Descrizione fisica",null,"1 online resource (456 p.)"]
[null,null,"Disciplina",null,"629.8042"]
[null,null,"Soggetti",null,"Microfluidics"]
[{"$nulls":4},"Nanofluids"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Cover; Title Page; Copyright; Contents; Preface; Part A: A Review of Essentials in Macrofluidics; Chapter 1 Theory; 1.1 Introduction and Overview; 1.2 Definitions and Concepts; 1.2.1 Definitions; 1.2.2 Flow Field Description; 1.2.3 Flow Field Categorization; 1.2.4 Thermodynamic Properties and Constitutive Equations; 1.3 Conservation Laws; 1.3.1 Derivation Approaches; 1.3.2 Reynolds Transport Theorem; 1.3.2.1 Fluid Mass Conservation in Integral Form; 1.3.2.2 Momentum Conservation in Integral Form; 1.3.2.3 Conservation Laws of Energy and Species Mass"]
[{"$nulls":4},"1.3.3 Conservation Equations in Differential Form1.3.3.1 Fluid Mass Conservation; 1.3.3.2 Linear Momentum Conservation; 1.3.3.3 Reduced Forms of the Momentum Equation; 1.3.3.4 Energy and Species Mass Conservation; 1.3.4 Entropy Generation Analysis; 1.4 Homework Assignments; 1.4.1 Physical Insight; 1.4.2 Text Problems; Chapter 2 Applications; 2.1 Internal Fluid Flow; 2.1.1 Problem-Solving Steps; 2.1.2 Sample Solutions of the Reduced Navier-Stokes Equations; 2.2 Porous Medium Flow; 2.3 Mixture Flows; 2.3.1 Introduction; 2.3.2 Modeling Approaches; 2.3.3 Homogeneous Flow Equations"]
[{"$nulls":4},"2.3.4 Non-Newtonian Fluid Flow2.3.5 Particle Transport; 2.4 Heat Transfer; 2.4.1 Forced Convection Heat Transfer; 2.4.2 Convection Heat Transfer Coefficient; 2.5 Convection-Diffusion Mass Transfer; 2.5.1 Modeling Approaches; 2.5.2 Compartmental Modeling; 2.6 Homework "]
[{"$nulls":4},"Assignments; 2.6.1 Definitions, Concepts, and Physical Insight; 2.6.2 Text Problem; 2.6.3 Homework Sets; 2.6.3.1 Homework Set Ia; 2.6.3.2 Homework Set Ib; 2.6.3.3 Homework Set IIa; 2.6.3.4 Homework Set IIb; References (Part A); Part B: Microfluidics; Chapter 3 Microchannel Flow Theory; 3.1 Introduction"]
[{"$nulls":4},"3.1.1 Microfluidic System Components3.1.2 Microfluidic System Integration; 3.1.3 Microfluidic System Challenges; 3.2 Basic Concepts and Limitations; 3.2.1 Scaling Laws; 3.2.2 Fluid Properties and Surface Tension Effects; 3.2.3 Wall Slip Velocity and Temperature Jump; 3.2.4 Electrokinetic Phenomena; 3.2.4.1 Electroosmosis; 3.2.4.2 Electrostatics; 3.2.4.3 Electrophoresis; 3.2.4.4 Nernst-Planck Equation; 3.2.5 Magnetohydrodynamics; 3.3 Homework Assignments; 3.3.1 Physical Insight; 3.3.2 Text Problems; Chapter 4 Applications in Microfluidics; 4.1 Introduction; 4.2 Micropumps and Microchannel Flow"]
[{"$nulls":4},"4.2.1 Micropumps4.2.2 Liquid Flow in Microchannels; 4.2.3 Gas Flow in Microchannels; 4.3 Micromixing; 4.4 Laboratory-on-a-Chip Devices; 4.4.1 LoC Processing Steps; 4.4.2 LoC Applications; 4.5 Homework Assignments and Course Projects; 4.5.1 Text-related Questions and Tasks; 4.5.2 Set-Up for Course Projects (CPs); References (Part B); Part C: Nanofluidics; Chapter 5 Fluid Flow and Nanofluid Flow in Nanoconduits; 5.1 Introduction; 5.1.1 Overview; 5.1.2 Nanostructures; 5.1.3 Nanothermodynamics; 5.2 Liquid Flow in Nanoconduits; 5.2.1 Introduction and Overview"]
[{"$nulls":4},"5.2.2 Nontraditional Simulation Methods"]
[null,null,null,"Sommario/riassunto","Fluidics originated as the description of pneumatic and hydraulic control systems, where fluids were employed (instead of electric currents) for signal transfer and processing. Microfluidics and Nanofluidics: Theory and Selected Applications offers an accessible, broad-based coverage of the basics through advanced applications of microfluidics and nanofluidics. It is essential reading for upper-level undergraduates and graduate students in engineering and professionals in industry."]
[null,"2.","Record Nr.",null,"UNINA9910138034503321"]
[null,null,"Titolo",null,"NMR of biomolecules : towards mechanistic systems biology / / edited by Ivano Bertini, Kathleen S. McGreevy, and Giacomo Parigi"]
[null,null,"Pubbl/distr/stampa",null,"Weinheim, : Wiley-VCH"]
[{"$nulls":4},"Chichester, : John Wiley [distributor], 2012"]
[null,null,"ISBN",null,"9781283644037"]
[{"$nulls":4},"1283644037"]
[{"$nulls":4},"9783527644520"]
[{"$nulls":4},"3527644520"]
[{"$nulls":4},"9783527644513"]
[{"$nulls":4},"3527644512"]
[{"$nulls":4},"9783527644506"]
[{"$nulls":4},"3527644504"]
[null,null,"Edizione",null,"[1st ed.]"]
[null,null,"Descrizione fisica",null,"1 online resource (653 p.)"]
[null,null,"Disciplina",null,"572"]
[null,null,"Soggetti",null,"Biomolecules"]
[{"$nulls":4},"Biological systems"]
[{"$nulls":4},"Nuclear magnetic resonance spectroscopy"]
[{"$nulls":4},"Systems biology"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographic references and index."]
[null,null,"Nota di contenuto",null,"NMR of Biomolecules: Towards Mechanistic Systems Biology; Contents; Preface; List of Contributors; List of Abbreviations; Part One: Introduction; 1 NMR and its Place in Mechanistic Systems Biology; 2 Structure of Biomolecules: Fundamentals; 2.1 Structural Features of Proteins; 2.1.1 Introduction: From Primary to Quaternary Structure; 2.1.2 Geometrical and Conformational Properties; 2.1.2.1 Backbone Dihedral Angles; 2.1.2.2 Side-Chain Dihedral Angles; 2.1.3 Secondary Structure Elements in Proteins; 2.1.4 Prediction of Secondary Structure"]
[{"$nulls":4},"2.1.5 Structural Motifs and Structural Domains - Combination of Secondary Structural Elements and Structural Motifs2.1.6 Types of Folds and their Classification; 2.1.6.1 Folds of the α Class; 2.1.6.2 Folds in the β Class; 2.1.6.3 Folds in the α/β Class; 2.1.6.4 Folds in the α + β Class; 2.1.7 Tertiary Structure; 2.1.8 Quaternary Structure; 2.2 Nucleic Acids; 2.2.1 Introduction; 2.2.1.1 Conformations; 2.2.2 DNA "]
[{"$nulls":4},"Structure; 2.2.2.1 B-DNA and Derivatives; 2.2.2.2 A-DNA; 2.2.2.3 Z-DNA; 2.2.2.4 Nonstandard DNA Structures; 2.2.2.4.1 Circular DNA; 2.2.2.4.2 Helical Junction; 2.2.2.4.3 Triple Helix"]
[{"$nulls":4},"2.2.2.4.4 i-Motif2.2.2.4.5 Quadruplex DNA; 2.2.3 RNA Structure; 2.2.3.1 Regular RNA Structure - A-Form Helices; 2.2.3.2 Mismatches, Bulges, and Unusual Base Pairing; 2.2.3.3 Reversal and Alteration of Strand Direction: Commonly Observed Loop and Turn Motifs; 2.2.3.3.1 U-Turn; 2.2.3.3.2 K-Turn; 2.2.3.3.3 C-Loop; 2.2.3.3.4 E-Loop; 2.2.3.4 Tetraloops and Tetraloop-Receptor Contact; 2.2.3.5 Higher-Order RNA Tertiary Structure Elements: Coaxial Stacking Motifs; 2.2.3.6 DNA-RNA Hybrids; 3 What Can be Learned About the Structure and Dynamics of Biomolecules from NMR; 3.1 Proteins Studied by NMR"]
[{"$nulls":4},"3.1.1 Why NMR Structures?3.1.2 NMR Bundle; 3.1.3 Protein Dynamics; 3.1.4 Intermolecular Interactions Involving Proteins; 3.2 Nucleic Acids Studied by NMR; 3.2.1 Structure, Mobility, and Function; Part Two: Role of NMR in the Study of the Structure and Dynamics of Biomolecules; 4 Determination of Protein Structure and Dynamics; 4.1 Determination of Protein Structures; 4.1.1 Resonance Assignment; 4.2 NMR Restraints; 4.2.1 Distance Restraints; 4.2.2 Dihedral Angles; 4.2.3 Residual Dipolar Couplings; 4.3 Structure Calculations; 4.3.1 Traditional; 4.3.2 Automated NOESY Assignment"]
[{"$nulls":4},"4.3.3 Energy Refinement of Protein Structures4.3.4 Chemical Shift-Based Approaches for Protein Structure Determination; 4.4 Validation of Protein Structures; 4.4.1 Experimental Data; 4.4.2 Geometric Quality; 4.5 Protein Dynamics and NMR Observables; 4.5.1 NMR Observables Affected by Dynamics; 4.5.2 NMR Experiments to Measure Dynamics and their Interpretation; 4.6 Protocols; 4.6.1 Sample Labeling; 4.6.2 NMR Assignment; 4.6.3 Manual Collection of Restraints; 4.6.4 Structure Calculations; 4.6.5 Structure Refinement; 4.6.6 Chemical Shift-Based Structure Calculations; 4.6.7 Structure Validation"]
[{"$nulls":4},"4.6.8 Protein Dynamics"]
[null,null,null,"Sommario/riassunto","NMR is one of the most powerful methods for imaging of biomolecules. This book is the ultimate NMR guide for researchers in the biomedical community and gives not only background and practical tips but also a forward looking view on the future of NMR in systems biology."]