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[null,"1.","Record Nr.",null,"UNINA9910831050903321"]
[null,null,"Titolo",null,"Development of the cardiac conduction system [[electronic resource]]"]
[null,null,"Pubbl/distr/stampa",null,"Chichester, UK ; ; Hoboken, NJ, : J. Wiley, 2003"]
[null,null,"ISBN",null,"1-280-27213-9"]
[{"$nulls":4},"9786610272136"]
[{"$nulls":4},"0-470-66781-8"]
[{"$nulls":4},"0-470-86803-1"]
[{"$nulls":4},"0-470-86806-6"]
[null,null,"Descrizione fisica",null,"1 online resource (301 p.)"]
[null,null,"Collana",null,"Novartis Foundation symposium ; ; 250"]
[null,null,"Disciplina",null,"612.1/71"]
[{"$nulls":4},"612.17"]
[null,null,"Soggetti",null,"Heart conduction system"]
[{"$nulls":4},"Heart - Growth"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","\"Symposium on Development of the Cardiac Conduction System, held at the Novartis Foundation, London, May 21-23, 2002\"--P. v."]
[{"$nulls":4},"Includes bibliographical references and index."]
[{"$nulls":4},"\"Editors, Derek J. Chadwick (organizer) and Jamie Goode\"--Contents p."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"DEVELOPMENT OF THE CARDIAC CONDUCTION SYSTEM; Contents; Participants; Chair's introduction; The morphology of the cardiac conduction system; Discussion; Development of the cardiac conduction system: a matter of chamber development; Discussion; Mouse models for cardiac conduction system development; Discussion; Developmental transitions in cardiac conduction; Discussion; Gap junctional connexins in developing mouse cardiac conduction system; Discussion; His-Purkinje lineages and development; Discussion; The role of neural crest and epicardium-derived cells in conduction system formation"]
[{"$nulls":4},"DiscussionInduction and patterning of the Purkinje fibre network; Discussion; The oldest, toughest cells in the heart; Discussion; Transcriptional regulation in the mouse atrioventricular conduction system; Discussion; Patterning of the mouse conduction system; Discussion; Clinical pathology of the cardiac conduction system; Discussion; Cardiac conduction and arrhythmia: insights from Nkx2.5 mutations in mouse and humans; Discussion; The genetic origin of atrioventricular conduction disturbance in humans; Discussion"]
[{"$nulls":4},"Defects in cardiac conduction system lineages and malignant arrhythmias: developmental pathways and diseaseDiscussion; Final general discussion; Index of contributors; Subject index"]
[null,null,null,"Sommario/riassunto","The pacemaking and conduction system (PCS) is vital for generating and synchronizing the heart beat.  Dysfunction of this system can be a direct cause of cardiac conduction disturbance, arrhythmias and sudden cardiac death. A wealth of information has been collected over many years on the unique histological, morphological and phenotypic characteristics of specialized cardiac tissues.  The cellular and molecular mechanisms that govern development of the PCS are now starting to be understood. This book draws together contributions from an international and interdisciplinary group of experts w"]
[null,"2.","Record Nr.",null,"UNINA9910816287703321"]
[null,null,"Titolo",null,"Evidence-based urology / / edited by Philipp Dahm, Roger Dmochowski"]
[null,null,"Pubbl/distr/stampa",null,"Hoboken, New Jersey : , : Wiley-Blackwell, , [2018]"]
[{"$nulls":4},"©2018"]
[null,null,"ISBN",null,"1-119-12989-3"]
[{"$nulls":4},"1-119-12987-7"]
[null,null,"Edizione",null,"[Second edition.]"]
[null,null,"Descrizione fisica",null,"1 online resource (617 pages)"]
[null,null,"Collana",null,"Evidence-based medicine series"]
[null,null,"Disciplina",null,"616.6"]
[null,null,"Soggetti",null,"Urology"]
[{"$nulls":4},"Genitourinary organs - Diseases"]
[{"$nulls":4},"Evidence-based medicine"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Intro -- Title Page -- Copyright Page -- Contents -- Contributors -- Part 1 Evidence-based methods -- Chapter 1 Searching for evidence -- The shape of clinical literature -- A case to consider -- What do you want? Asking a focused clinical question -- Searching for clinical evidence: start with synthesized sources -- Point-of-care summaries -- Practice guidelines -- Systematic reviews -- Textbooks and handbooks -- Searching for clinical evidence: try preappraised sources next -- Searching for clinical evidence: filtering unfiltered databases -- Other databases -- Backing up your search: citation searching. Evidence your patients can understandConclusion -- References -- Chapter 2 Clinical trials in urology -- Introduction -- The hierarchy of evidence -- Clinical trial design elements: safeguarding against bias -- Clinical trial analysis elements: safeguarding against bias -- Applying clinical trial results -- Pragmatic clinical trials -- Conclusion -- References -- Chapter 3 Systematic reviews in urology -- Introduction -- How to perform a systematic review -- Using existing systematic reviews -- Conclusion -- References -- Chapter 4 Rating the quality of evidence and making recommendations -- Introduction. Question formulation and recommendations in this bookEvaluating the quality of evidence and making recommendations -- Strength of the recommendation -- Interpreting strong and weak recommendations -- How methodological quality of the evidence contributes to the strength of recommendation -- Factors that decrease the quality of evidence -- "]
[{"$nulls":4},"Factors that increase the quality of evidence -- What to do when strength of evidence differs across outcomes? -- Interpreting recommendations -- Conclusion -- References -- Chapter 5 Evidence-based clinical practice guidelines in urology -- Introduction. Guideline creation checklistConclusions -- References -- Chapter 6 Understanding concepts related to health economics in urology -- Introduction -- Economic parameters -- The importance of perspective -- Cost versus charge -- Discounting -- Costs in economic evaluation -- Health service costs -- Non-health service costs -- Economic analyses -- Additional utility in cost efficacy -- Conclusion -- References -- Chapter 7 Quality improvement in urology -- Introduction -- Background -- Defining quality -- Quality measures -- Frameworks for quality improvement -- Conclusions -- References -- Part 2 General urology and stone disease. Chapter 8 Antibiotic prophylaxis in urological surgeryIntroduction -- Clinical question 1 -- Clinical question 2 -- Clinical question 3 -- Clinical question 4 -- Future considerations -- References -- Chapter 9 Venous thromboembolism (VTE) prophylaxis -- Introduction -- Literature search -- Clinical question 1 -- Clinical question 2 -- Clinical question 3 -- Clinical question 4 -- References -- Studies sourced (per EAU guidelines on thromboprophylaxis in urological surgery (2017)) -- Chapter 10 Operative safety -- Background -- Clinical question 1 -- Clinical question 2 -- Clinical question 3 -- References."]
[null,null,null,"Sommario/riassunto","\"This book is an invaluable source of evidence-based information distilled into guidance for clinical practice, and addresses all the major clinical questions encountered by urologists every day. Unique it its 100% evidence-based approach, it is an essential tool for urologists of all levels to consult time and time again\"--Provided by publisher."]