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[null,"1.","Record Nr.",null,"UNINA9910791892003321"]
[null,null,"Titolo",null,"Handbook of adaptive designs in pharmaceutical and clinical development / / edited by Annpey Pong, Shein-Chung Chow"]
[null,null,"Pubbl/distr/stampa",null,"Boca Raton : , : CRC Press, , 2011"]
[null,null,"ISBN",null,"0-429-13066-X"]
[{"$nulls":4},"1-283-00453-4"]
[{"$nulls":4},"9786613004536"]
[{"$nulls":4},"1-4398-1017-6"]
[null,null,"Descrizione fisica",null,"1 online resource (475 p.)"]
[null,null,"Disciplina",null,"615.5072/4"]
[null,null,"Soggetti",null,"Clinical trials"]
[{"$nulls":4},"Drugs - Research - Methodology"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Front cover; Contents; Preface; Editors; Contributors; Chapter 1. Overview of Adaptive Design Methods in Clinical Trials; Chapter 2. Fundamental Theory of Adaptive Designs with Unplanned Design Change in Clinical Trials with Blinded Data; Chapter 3. Bayesian Approach for Adaptive Design; Chapter 4. The Impact of Protocol Amendments in Adaptive Trial Designs; Chapter 5. From Group Sequential to Adaptive Designs; Chapter 6. Determining Sample Size for Classical Designs; Chapter 7. Sample Size Reestimation Design with Applications in Clinical Trials"]
[{"$nulls":4},"Chapter 8. Adaptive Interim Analyses in Clinical TrialsChapter 9. Classical Dose-Finding Trial; Chapter 10. Improving Dose-Finding: A Philosophic View; Chapter 11. Adaptive Dose-Ranging Studies; Chapter 12. Seamless Phase I/II Designs; Chapter 13. Phase II/III Seamless Designs; Chapter 14. Sample Size Estimation/Allocation for Two-Stage Seamless Adaptive Trial Designs; Chapter 15. Optimal Response-Adaptive Randomization for Clinical Trials; Chapter 16. Hypothesis-Adaptive Design; Chapter 17. Treatment Adaptive Allocations in Randomized Clinical Trials: An Overview"]
[{"$nulls":4},"Chapter 18. Integration of Predictive Biomarker Diagnostics into Clinical Trials for New Drug DevelopmentChapter 19. Clinical Strategy for Study Endpoint Selection; Chapter 20. Adaptive Infrastructure; Chapter 21. Independent Data Monitoring Committees; Chapter 22. Targeted "]
[{"$nulls":4},"Clinical Trials; Chapter 23. Functional Genome-Wide Association Studies of Longitudinal Traits; Chapter 24. Adaptive Trial Simulation; Chapter 25. Efficiency of Adaptive Designs; Chapter 26. Case Studies in Adaptive Design; Chapter 27. Good Practices for Adaptive Clinical Trials; Back cover"]
[null,null,null,"Sommario/riassunto","This comprehensive guide offers a unified presentation of the principles and methodologies in adaptive design and analysis. It gives a well-balanced summary of current regulatory perspectives and recently developed statistical methods in this area. The handbook provides some insight regarding early phase and later phase adaptive designs. With a focus on the implementation of adaptive methods in clinical trials, it introduces the concepts of role, responsibility, function, and activity of a data safety monitoring board (DSMB) when applying these methods. Other important topics covered in detail include regulatory perspectives and logistics issues in applying adaptive design methods--Provided by publisher."]
[null,"2.","Record Nr.",null,"UNINA9910812855903321"]
[null,null,"Autore",null,"Spencer Douglas"]
[null,null,"Titolo",null,"The architecture of neoliberalism : how contemporary architecture became an instrument of control and compliance / / Douglas Spencer"]
[null,null,"Pubbl/distr/stampa",null,"London, England : , : Bloomsbury Academic, , 2020"]
[{"$nulls":4},"London, England : , : Bloomsbury Publishing, , 2020"]
[null,null,"ISBN",null,"1-350-37590-X"]
[{"$nulls":4},"1-4725-8153-9"]
[{"$nulls":4},"1-4725-8154-7"]
[null,null,"Descrizione fisica",null,"1 online resource (229 pages)"]
[null,null,"Collana",null,"Online access with DDA: Askews (Architecture)"]
[null,null,"Classificazione",null,"ARC001000ARC005080POL042020"]
[null,null,"Disciplina",null,"720.1/03"]
[null,null,"Soggetti",null,"Architecture and society"]
[{"$nulls":4},"Architecture - Political aspects"]
[{"$nulls":4},"Neoliberalism"]
[{"$nulls":4},"Architecture"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Title Page; Copyright Page; Contents ; List of Illustrations; Acknowledgements; Preface; Introduction: Architecture, Neoliberalism and the Game of Truth ; Chapter 1 Necessary Ignorance: The Art of Neoliberal Governmentality ; Foucault and governmentality ; Neoliberalism, human capital and the entrepreneurial self ; Hayek, Polanyi and cybernetics ; Spontaneous orders and complex systems ; Neoliberalism as the ' form of our existence ' ; Chapter 2 The Spatial Constitution of the Neoliberal Subject ; Hamilton, Pollock and Kaprow."]
[{"$nulls":4},"THX 1138 and Alphaville The counterculture and the technical mentality ; Banham, Baudrillard and McLuhan ; Chapter 3 Architectural Theory: From May 68 to the ' Real ' of the Market ; Post-theory and the post-political ; Architecture and Deleuze ; The new agenda for architecture ; Architecture and the market ; DeLanda, Latour and Luhmann ; The real subsumption of theory ; Chapter 4 Labour Theory: Architecture, Work and Neoliberalism ; Architecture and the image of labour ; Ubiquitous workspace."]
[{"$nulls":4},"Boltanski and Chiapello, Postone, and the thesis of ' immaterial labour ' Zaha Hadid Architects and BMW Leipzig ; The urban diagram of the new factory ; Koolhaas, OMA and CCTV ; Architecture as infrastructure ; Circulation as labour and image ; Chapter 5 Festivals of Circulation: "]
[{"$nulls":4},"Neoliberal Architectures of Culture, Commerce and Education ; The Pompidou as Fun Palace ; Crowd modelling ; Citizen-consumers: FOA ' s Meydan Retail Complex ; Student-entrepreneurs: Formatting the subject of education."]
[null,null,null,"Sommario/riassunto","\"Neoliberalism is a project to remake us, and our world, according to a purely economic rationality. In societies where the logic of the market reigns unopposed we must fashion our lives as entrepreneurial endeavors. We must be networked, in constant circulation, opportunistic. The Architecture of Neoliberalism pursues an uncompromising critique of architecture's part in this neoliberal turn. This book reveals how a self-styled parametric, post-critical and projection architecture serves mechanisms of control and compliance while promoting itself as progressive.\"--Provided by publisher."]