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[null,"1.","Record Nr.",null,"UNINA9910800162803321"]
[null,null,"Titolo",null,"Cyclic nucleotide signaling / / edited by Xiaodong Cheng"]
[null,null,"Pubbl/distr/stampa",null,"Boca Raton, Florida : , : CRC Press, , [2015]"]
[{"$nulls":4},"©2015"]
[null,null,"ISBN",null,"0-429-16192-1"]
[{"$nulls":4},"1-4822-3557-9"]
[null,null,"Descrizione fisica",null,"1 online resource (282 p.)"]
[null,null,"Collana",null,"Methods in Signal Transduction Series"]
[null,null,"Disciplina",null,"571.7/4"]
[null,null,"Soggetti",null,"Cyclic nucleotides"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references at the end of each chapters."]
[null,null,"Nota di contenuto",null,"Front Cover; Contents; Series Preface; Preface; Editor; Contributors; Chapter 1: Discovery of Small Molecule EPAC Specific Modulators by High-Throughput Screening; Chapter 2: Cyclic Nucleotide Analogs as Pharmacological Tools for Studying Signaling Pathways; Chapter 3: High-Throughput FRET Assays for Fast Time-Dependent Detection of Cyclic AMP in Pancreatic β Cells; Chapter 4: Assessing Cyclic Nucleotide Recognition in Cells : Opportunities and Pitfalls for Selective Receptor Activation; Chapter 5: Monitoring Cyclic Nucleotides Using Genetically Encoded Fluorescent Reporters"]
[{"$nulls":4},"Chapter 6: Structural Characterization of Epac by X-Ray CrystallographyChapter 7: Sensory Neuron cAMP Signaling in Chronic Pain; Chapter 8: Monitoring Real-Time Cyclic Nucleotide Dynamics in Subcellular Microdomains; Chapter 9: Identifying Complexes of Adenylyl Cyclase with A-Kinase Anchoring Proteins; Chapter 10: Assessing Cyclic Nucleotide Binding Domain Allostery and Dynamics by NMR Spectroscopy; Chapter 11: A Protocol for Expression and Purification of Cyclic Nucleotide-Free Protein in Escherichia coli; Chapter 12: Cyclic Nucleotide Analogues as Chemical Tools for Interaction Analysis"]
[{"$nulls":4},"Chapter 13: Dissecting the Physiological Functions of PKA Using Genetically Modified MiceBack Cover"]
[null,null,null,"Sommario/riassunto","<P>Showcasing the recent progresses of the field, <B>Cyclic Nucleotide Signaling<I> </B></I>covers the major tools and methodologies used in various areas of research. The majority of the chapters are protocol oriented, with the goal of providing clear "]
[{"$nulls":4},"directions for laboratory use. Students and investigators new to the field will find this book particularly informative, as will scientists already actively researching nucleotide signaling.</P>"]