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[null,"1.","Record Nr.",null,"UNINA9910452690803321"]
[null,null,"Autore",null,"Endres Robert G"]
[null,null,"Titolo",null,"Physical principles in sensing and signaling [[electronic resource] ] : with an introduction to modeling in biology / / Robert G. Endres"]
[null,null,"Pubbl/distr/stampa",null,"Oxford, : Oxford University Press, 2013"]
[null,null,"ISBN",null,"1-283-85621-2"]
[{"$nulls":4},"0-19-165428-0"]
[null,null,"Descrizione fisica",null,"1 online resource (158 p.)"]
[null,null,"Disciplina",null,"571.43"]
[{"$nulls":4},"571.634"]
[null,null,"Soggetti",null,"Biology - Simulation methods"]
[{"$nulls":4},"Biology - Mathematical models"]
[{"$nulls":4},"Electronic books."]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Cover; Contents; 1 Introduction; Chapter summary; Further reading; 2 Chemotaxis in bacterium Escherichia coli; 2.1 Chemical gradient sensing; 2.2 \"Nose and brain\": the receptor cluster; 2.3 E. coli chemotaxis pathway; 2.4 Experimental approaches; 2.5 Time-course data and dose-response curves; Chapter summary; Further reading; 3 Physical concepts; 3.1 Diffusion; 3.2 Boltzmann distribution; 3.3 Ligand-receptor binding; 3.4 Fluctuation-dissipation theorem; Chapter summary; Further reading; 4 Mathematical tools; 4.1 Ordinary differential equations; 4.2 Kinetic laws; 4.3 Master equation"]
[{"$nulls":4},"4.4 Poisson distribution4.5 Waiting-time distribution; 4.6 Langevin small-noise approximation; 4.7 Information theory; Chapter summary; Further reading; 5 Signal amplification and integration; 5.1 Cooperativity by allostery; 5.2 Emergence of allostery from microscopic details; 5.3 Two-state equilibrium receptor model; 5.4 Monod-Wyman-Changeux model for receptor signaling; 5.5 Alternative Ising model for receptor cluster; Chapter summary; Further reading; 6 Robust precise adaptation; 6.1 Energy-landscape picture of adaptation; 6.2 Dynamics of adaptation; 6.3 Chemotactic response function"]
[{"$nulls":4},"6.4 Integral-feedback control6.5 Assistance neighborhoods; Chapter summary; Further reading; 7 Polar receptor localization and clustering; 7.1 Trimer of dimers; 7.2 Elastic cluster-membrane model; 7.3 Polar receptor clustering; Chapter summary; Further reading; 8 Accuracy of "]
[{"$nulls":4},"sensing; 8.1 Perfectly absorbing sphere; 8.2 Perfectly monitoring sphere; 8.3 Sensing with cell-surface receptors; Chapter summary; Further reading; 9 Motor impulse response; 9.1 Impulse response; 9.2 Time and frequency domains; 9.3 Minimal pathway model; 9.4 Linear response approximation; 9.5 Noise power spectra"]
[{"$nulls":4},"Chapter summaryFurther reading; 10 Optimization of pathway; 10.1 Optimal receptor-complex size; 10.2 Optimal adaptation dynamics; Chapter summary; Further reading; 11 \"Seeing like a bacterium\"; 11.1 Typical chemical gradients; 11.2 Weber's law; 11.3 Perception; 11.4 Fold-change detection; 11.5 Matching relations; 11.6 Predicting typical stimuli; Chapter summary; Further reading; 12 Beyond E. coli chemotaxis; Chapter summary; Further reading; Appendix More techniques; A.1 Derivation of the fluctuation-dissipation theorem; A.2 Variational principles and the Euler-Lagrange equation"]
[{"$nulls":4},"A.3 Gillespie simulationsA.4 Fokker-Planck approximation; A.5 Derivation of the Langevin noise; A.6 Time versus frequency domain; A.7 Model fitting to data; A.8 Principal component analysis; Chapter summary; Further reading; Index; A; B; C; D; E; F; G; H; I; L; M; N; O; P; Q; R; S; T; V; W"]
[null,null,null,"Sommario/riassunto","Although invisible to the bare eye, bacterial cells are large enough to make complex decisions. Cells are composed of thousands of different molecular species including DNA, proteins, and smaller molecules, allowing them to sense their environment, to process this information, and to respond accordingly. Such responses include expression of genes or the control of their movement. Despite these properties, a living cell exists in the physical world and follows its laws. Keeping thisin mind can help answer questions such as how cells work and why they implement solutions to problems the way they"]
[null,"2.","Record Nr.",null,"UNINA9910798601903321"]
[null,null,"Autore",null,"Carlen Joe"]
[null,null,"Titolo",null,"A brief history of entrepreneurship : the pioneers, profiteers, and racketeers who shaped our world / / Joe Carlen"]
[null,null,"Pubbl/distr/stampa",null,"New York : , : Columbia University Press, , 2016"]
[{"$nulls":4},"©2016"]
[null,null,"ISBN",null,"0-231-54281-X"]
[null,null,"Descrizione fisica",null,"1 online resource (252 pages)"]
[null,null,"Collana",null,"Columbia Business School Publishing"]
[null,null,"Disciplina",null,"338/.0409"]
[null,null,"Soggetti",null,"Commerce - History"]
[{"$nulls":4},"Entrepreneurship - History"]
[{"$nulls":4},"Businesspeople - History"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Includes index."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Frontmatter -- Contents -- Introduction -- 1. \"One Shekel of Your Private Silver\" -- 2. The Pirates of Phoenicia -- 3. The Reluctant Romans -- 4. An Enterprising Faith -- 5. Flying Money and Capitalist Monks -- 6. Western Europe and a \"New World\" of Profit -- 7. Captains of the Revolution -- 8. The Land of (Entrepreneurial) Opportunity -- 9. Flattening the World and Colonizing Space -- Conclusion -- Notes -- Acknowledgments -- Index"]
[null,null,null,"Sommario/riassunto","A Brief History of Entrepreneurship charts how the pursuit of profit by private individuals has been a prime mover in revolutionizing civilization. Entrepreneurs often butt up against processes, technologies, social conventions, and even laws. So they circumvent, innovate, and violate to obtain what they want. This creative destruction has brought about overland and overseas trade, colonization, and a host of revolutionary technologies-from caffeinated beverages to the personal computer-that have transformed society.Consulting rich archival sources, including some that have never before been translated, Carlen maps the course of human history through nine episodes when entrepreneurship reshaped our world. Highlighting the most colorful characters of each era, he discusses Mesopotamian merchants' creation of the urban market economy; Phoenician merchant-sailors intercontinental trade, which came to connect Africa, Asia, and Europe; Chinese tea traders' invention of paper money; the colonization of the Americas; and the current \"flattening\" of the world's "]
[{"$nulls":4},"economic playing field. Yet the pursuit of profit hasn't always moved us forward. From slavery to organized crime, Carlen explores how entrepreneurship can sometimes work at the expense of others. He also discusses the new entrepreneurs who, through the nascent space tourism industry, are leading humanity to a multiplanetary future. By exploring all sides of this legacy, Carlen brings much-needed detail to the role of entrepreneurship in revolutionizing civilization."]