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[null,"1.","Record Nr.",null,"UNINA9910784598503321"]
[null,null,"Titolo",null,"Advances in antiviral drug design . Volume 5 [[electronic resource] /] / editor, E. De Clercq"]
[null,null,"Pubbl/distr/stampa",null,"Greenwich, CT ; ; London, England, : Jai Press, 2007"]
[null,null,"ISBN",null,"1-281-11983-0"]
[{"$nulls":4},"9786611119836"]
[{"$nulls":4},"0-08-054824-5"]
[null,null,"Descrizione fisica",null,"1 online resource (265 p.)"]
[null,null,"Collana",null,"Advances in antiviral drug design ; ; 5"]
[null,null,"Disciplina",null,"616.9"]
[{"$nulls":4},"616.9/25061/05"]
[{"$nulls":4},"616.91061"]
[null,null,"Soggetti",null,"Antiviral agents"]
[{"$nulls":4},"Anti-infective agents"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"I. IntroductionII. Design; III. Synthesis; IV. Antiviral activity; Acknowledgements; References; Chapter 4. Synthesis and antiviral evaluation of broad spectrum, orally active analogs of cidofovir and other acyclic nucleoside phosphonates; I. Introduction; II. Synthesis of hexadecyloxypropyl and related esters of cidofovir; III. Antiviral evaluation and spectrum of activity; IV. Structure activity relationships; V. Cellular metabolism; VI. Oral pharmacokinetics and tissue distribution; VII. Antiviral activity in animal models of viral diseases"]
[{"$nulls":4},"VIII. Alkoxyalkyl esters of (S)-HPMPA and other acyclic nucleoside phosphonatesIX. Conclusions; Acknowledgements; References; Chapter 5. CCR5 antagonistsCCR5 antagonists for the treatment ofHIV infection and AIDS; I. Introduction; II. Inhibition of HIV entry; III. CCR5 as a drug target; IV. The discovery of novel CCR5 antagonists; V. Molecular mechanisms; VI. Resistance to CCR5 antagonists in vitro and in the clinic; VII. Conclusions; References; Chapter 6. The medicinal chemistry of the DATADATA and DAPYDAPY series of HIV-1HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIsNNRTIs)"]
[{"$nulls":4},"AbstractI. Introduction; II. The diaryltriazine (DATA) series; III. The diarylpyrimidine (DAPY) series; IV. Conclusion; Acknowledgements; References; Index"]
[null,null,null,"Sommario/riassunto","Regularly reviewing the \"\"state-of-the-art\"\" developments in the "]
[{"$nulls":4},"antiviral drug research field, this latest volume spans the conceptual design and chemical synthesis of new antiviral compounds. It discusses their structure-activity relationship, mechanism and targets of action, pharmacological behavior, antiviral activity spectrum, and therapeutic potential for clinical use."]
[null,"2.","Record Nr.",null,"UNINA9910797661903321"]
[null,null,"Autore",null,"Lelekis Debbie"]
[null,null,"Titolo",null,"American literature, lynching, and the spectator in the crowd : spectacular violence / / Debbie Lelekis"]
[null,null,"Pubbl/distr/stampa",null,"Lanham [Maryland] : , : Lexington Books, , [2015]"]
[{"$nulls":4},"©2015"]
[null,null,"ISBN",null,"1-4985-0636-4"]
[null,null,"Descrizione fisica",null,"1 online resource (127 p.)"]
[null,null,"Disciplina",null,"810.9/3552"]
[null,null,"Soggetti",null,"American literature - 20th century - History and criticism - Theory, etc"]
[{"$nulls":4},"Narration (Rhetoric)"]
[{"$nulls":4},"Spectators in literature"]
[{"$nulls":4},"Point of view (Literature)"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"A critical introduction: spectatorship and the evolution of crowds in literature the intersection of journalism, politics, and fiction -- Reporting the crowd -- The female reporter as spectator and spectacle -- Confronting the crowd and vigilante violence -- Recounting the horror of the spectacle."]
[null,null,null,"Sommario/riassunto","American Literature, Lynching, and the Spectator in the Crowd: Spectacular Violence examines spectatorship in texts by Theodore Dreiser, Miriam Michelson, Irvin S. Cobb, and Paul Laurence Dunbar. As a figure who is simultaneously within and outside the crowd, the spectator (often in the form of a reporter character) is in a unique position to express the fractures between the individual and the collective in American society, seen most vividly in fictional lynch mob scenes in American literature at the turn of the twentieth century."]