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[null,"1.","Record Nr.",null,"UNINA9910792273803321"]
[null,null,"Autore",null,"Vijg Jan"]
[null,null,"Titolo",null,"Aging of the genome [[electronic resource] ] : the dual role of DNA in life and death / / Jan Vijg"]
[null,null,"Pubbl/distr/stampa",null,"Oxford, : Oxford University Press, 2007"]
[null,null,"ISBN",null,"9786611145255"]
[{"$nulls":4},"1-281-14525-4"]
[{"$nulls":4},"0-19-856922-X"]
[{"$nulls":4},"0-19-152458-1"]
[{"$nulls":4},"1-4294-6993-5"]
[null,null,"Descrizione fisica",null,"1 online resource (385 p.)"]
[null,null,"Disciplina",null,"571.878"]
[null,null,"Soggetti",null,"Aging - Genetic aspects"]
[{"$nulls":4},"Genomes"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references."]
[null,null,"Nota di contenuto",null,"Contents; Preface; 1 Introduction: the coming of age of the genome; 1.1 The age of biology; 1.2 From genetics to genomics; 1.3 A return to function; 1.4 The causes of aging: a random affair; 2 The logic of aging; 2.1 Aging genes; 2.2 Pleiotropy in aging; 2.3 Interrupting the pathways of aging; 2.4 Longevity-assurance genes; 2.5 Somatic damage and the aging genome; 3 Genome structure and function; 3.1 DNA primary structure; 3.2 Higher-order DNA structure; 3.3 Nuclear architecture; 3.4 Transcription regulation; 3.5 Conclusions; 4 Genome maintenance; 4.1 Why genome maintenance?"]
[{"$nulls":4},"4.2 DNA-damage signaling and cellular responses4.3 DNA-repair mechanisms; 4.4 Genome maintenance and aging; 5 Genome instability and accerated aging; 5.1 Premature aging; 5.2 Validity of accelerated-aging phenotypes; 5.3 Genome maintenance and accelerated aging in mice; 5.4 Conclusions; 6 The aging genome; 6.1 DNA damage; 6.2 DNA-sequence changes; 6.3 Changes in DNA modification and conformation; 6.4 Summary and conclusions: a DNA damage report of aging; 7 From genome to phenome; 7.1 The causes of cancer; 7.2 Genome instability and tissue dysfunction"]
[{"$nulls":4},"7.3 Testing the role of genome instability in aging8 A genomic limit to life?; 8.1 Aiming for immortality; 8.2 SENS, and does it make sense?; EPILOGUE; GLOSSARY; A; B; C; D; E; F; G; H; I; L; M; N; O; P; R; S; T; X; Y; "]
[{"$nulls":4},"Z; REFERENCES; INDEX; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; Q; R; S; T; U; V; W; X; Y; Z"]
[null,null,null,"Sommario/riassunto","Aging has long been ascribed to the gradual accumulation of mutations in the genome. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. This book reviews the concept of genomic instability as a possible universal cause of aging in complex organisms resulting from recent advances in functional genomics and systems biology. - ;Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technol"]
[null,"2.","Record Nr.",null,"UNINA9910800074503321"]
[null,null,"Autore",null,"Garbacz Bader Donna M."]
[null,null,"Titolo",null,"Forensic nursing : a concise manual / / Donna M. Garbacz Bader, Sue Gabriel"]
[null,null,"Pubbl/distr/stampa",null,"Boca Raton, Fla. : , : Taylor & Francis, , 2010"]
[null,null,"ISBN",null,"0-429-24934-9"]
[{"$nulls":4},"1-282-31209-X"]
[{"$nulls":4},"9786612312090"]
[{"$nulls":4},"1-4200-6731-1"]
[null,null,"Descrizione fisica",null,"1 online resource (464 p.)"]
[null,null,"Disciplina",null,"614/.1"]
[null,null,"Soggetti",null,"Forensic nursing"]
[{"$nulls":4},"Medical jurisprudence"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","A CRC title."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Front cover; Dedication; Table of Contents; Foreword; Preface; About the Editors; Contributors; Introduction; Chapter 1. Forensic Nursing; Chapter 2. Forensic Nursing Today; Chapter 3. Forensic Nursing Education Guidelines and Qualifications; Chapter 4. Educational Foundation for Forensic Nursing Practice; Chapter 5. Forensic Science; Chapter 6. Coroners, Medical Examiners, and Forensic Pathologists; Chapter 7. Cause, Manner, and Mechanism of Death; Chapter 8. Crime Scene Investigation; Chapter 9. Forensic Nursing Crime Scene Investigation"]
[{"$nulls":4},"Chapter 10. Establishing Time of Death and Injury: Forensic Nursing Practice and ResponsibilityChapter 11. Chain of Custody and Identification, Collection, and Preservation of Evidence: Major Concepts of Forensic Nursing; Chapter 12. Significance of an Autopsy; Chapter 13. The Nursing Process; Chapter 14. Forensic Nursing and the Law; Chapter 15. Forensic Nurse as an Expert Witness; Chapter 16. The Perpetrator: A Victim and a Patient; Chapter 17. Ethics and Forensic Nursing Practice; Chapter 18. Psychosocial Aspects of Crime; Chapter 19. Deaths in Nursing Homes"]
[{"$nulls":4},"Chapter 20. Excited Delirium Syndrome (EDS)Chapter 21. Blunt Force Injuries; Chapter 22. Sharp Force Trauma; Chapter 23. Gunshot Wounds; Chapter 24. Asphyxia; Chapter 25. Child Abuse; Chapter 26. Sexual Assault; Chapter 27. Intimate Partner Violence; Chapter 28. "]
[{"$nulls":4},"Cyberspace Crimes against Children; Chapter 29. Human Trafficking; Chapter 30. Mass Disasters; Chapter 31. Additional Violence in Society; Chapter 32. Emergency Department Dos and Don'ts; Chapter 33. Bridging the Gap between the Living and the Nonliving; Chapter 34. Profiling"]
[{"$nulls":4},"Chapter 35. From Crime Scene to Morgue: The Field of Forensic AnthropologyAppendix: Medicolegal Death Scene Investigation; Index; Back cover"]
[null,null,null,"Sommario/riassunto","The forensic nurse has a powerful role in medical-legal investigations. Going beyond the nurse's traditional role, forensic nurses are often at the forefront of evidence collection and preservation. They can maintain an evidentiary chain of custody, testify as an expert witness in a court of law, care for victims, assist victims' families, and work with the community and law enforcement by providing educational programs. Forensic Nursing: A Concise Manual presents practical information directed at the range of activities that forensic nurses perform, offering guidelines for"]