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[null,"1.","Record Nr.",null,"UNINA9910790969803321"]
[null,null,"Autore",null,"Gullotta Thomas P"]
[null,null,"Titolo",null,"Delinquent Violent Youth [[electronic resource] ] : Theory and Interventions"]
[null,null,"Pubbl/distr/stampa",null,"Thousand Oaks, : SAGE Publications, 1997"]
[null,null,"ISBN",null,"1-4522-5039-1"]
[null,null,"Descrizione fisica",null,"1 online resource (329 p.)"]
[null,null,"Collana",null,"Advances in Adolescent Development"]
[null,null,"Disciplina",null,"364.36"]
[null,null,"Soggetti",null,"Adolescent Behavior"]
[{"$nulls":4},"Juvenile delinquency -- Prevention"]
[{"$nulls":4},"Juvenile Delinquency"]
[{"$nulls":4},"At-risk youth - Behavior modification"]
[{"$nulls":4},"Violence -- in adolescence"]
[{"$nulls":4},"Violence in children"]
[{"$nulls":4},"Social Problems"]
[{"$nulls":4},"Crime"]
[{"$nulls":4},"Behavior"]
[{"$nulls":4},"Age Groups"]
[{"$nulls":4},"Sociology"]
[{"$nulls":4},"Behavior and Behavior Mechanisms"]
[{"$nulls":4},"Persons"]
[{"$nulls":4},"Criminology"]
[{"$nulls":4},"Social Sciences"]
[{"$nulls":4},"Mental Disorders"]
[{"$nulls":4},"Adolescent"]
[{"$nulls":4},"Violence"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,"Nota di contenuto",null,"Cover; Contents; Introduction; Chapter 1 - Reflections on Delinquency, Dickens, and Twain; Chapter 2 - Juvenile Justice and Delinquency Prevention in the United States: The Influence of Theories and Traditions on Policies and Practices; Chapter 3 - The Influence of Families, Friends, Schools, and Community on Delinquent Behavior; Chapter 4 - Adolescent Drug Use, Delinquency, and Other Behaviors; Chapter 5 - Life Imitating Art: Adolescents and Television Violence; "]
[{"$nulls":4},"Chapter 6 - Violent Offending in Adolescence: Epidemiology, Correlates, Outcomes, and Treatment"]
[{"$nulls":4},"Chapter 7 - Youth Gangs: A Developmental PerspectiveChapter 8 - A Comprehensive Review of Community-Based Approaches for the Treatment of Juvenile Offenders; Chapter 9 - Incarcerated Juvenile Offenders: Integrating Trauma-Oriented Treatment with State-of-the-Art Delinquency Interventions; Chapter 10 - Preventing Juvenile Delinquency and Promoting Juvenile Rightency; Index; About the Editors; About the Contributors"]
[null,null,null,"Sommario/riassunto","This interdisciplinary volume provides a wide-ranging overview of the causes of criminal behaviour in children and adolescents.    Following a literary and historical introduction, the contributors to this volume explore the theory and social policy that have shaped society's responses to young people in trouble. They then examine a number of key current issues, including: how families, peers, schools and the community influence delinquent behaviour; the role of substance abuse; the influence of television on violent behaviour; the nature and treatment of violent behaviour in adolesc"]
[null,"2.","Record Nr.",null,"UNINA9910424631003321"]
[null,null,"Autore",null,"Carlberg Carsten"]
[null,null,"Titolo",null,"Mechanisms of Gene Regulation: How Science Works / / by Carsten Carlberg, Ferdinand Molnár"]
[null,null,"Pubbl/distr/stampa",null,"Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020"]
[null,null,"ISBN",null,"3-030-52321-7"]
[null,null,"Edizione",null,"[1st ed. 2020.]"]
[null,null,"Descrizione fisica",null,"1 online resource (XVI, 149 p. 71 illus., 70 illus. in color.)"]
[null,null,"Disciplina",null,"572.865"]
[null,null,"Soggetti",null,"Medicine - Research"]
[{"$nulls":4},"Biology - Research"]
[{"$nulls":4},"Biochemistry"]
[{"$nulls":4},"Genetics"]
[{"$nulls":4},"Biomedical Research"]
[{"$nulls":4},"Genetics and Genomics"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Nota di bibliografia","Includes bibliographical references."]
[null,null,"Nota di contenuto",null,"Central dogma of molecular biology -- Impact of chromatin structure -- Epigenetics enables gene expression -- Gene regulation in the context of nuclear architecture -- Core promoter -- TATA box and other core promoter elements -- Genome-wide core promoter identification -- TFIID and Mediator as paradigms of multi-protein complexes -- Site-specific transcription factors and their domains -- Classification of transcription factors -- Activation of transcription factors -- Programing cellular differentiation by transcription factors -- Inflammatory signaling via NF-KB -- Sensing cellular stress via p53 -- The nuclear receptor superfamily -- Molecular interactions of nuclear receptors -- Physiological role of nuclear receptors -- Next-generation sequencing -- Gene regulation in the context of Big Biology -- Exploring genome-wide transcription factor binding -- Integrating epigenome-wide datasets -- Cytosines and their methylation -- Histone modifications -- Gene regulation via chromatin modifiers -- Sensing energy metabolism via chromatin modifiers -- Epigenetics and chromatin -- Genome-wide understanding of epigenetics -- CTCF and genetic imprinting -- Epigenetics in health and disease -- Nucleosome positioning at promoters -- Chromatin remodeling -- Transcriptional dynamics in the presence of chromatin -- Organization of the nucleus "]
[{"$nulls":4},"-- Non-coding RNAs -- miRNAs and their regulatory potential -- Long ncRNAs -- Enhancer RNAs."]
[null,null,null,"Sommario/riassunto","This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of gene expression is a fundamental aspect of nearly all processes in physiology, both in healthy and in diseased states. Th is pivotal role for the regulation of gene expression makes this textbook essential reading for students of all the biomedical sciences, in order to be better prepared for their specialized disciplines. A complete understanding of transcription factors and the processes that alter their activity is a major goal of modern life science research. The availability of the whole human genome sequence (and that of other eukaryotic genomes) and the consequent development of next-generation sequencing technologies have significantly changed nearly all areas of the biological sciences. For example, the genome-wide location of histone modifications and transcription factor binding sites, such as provided by the ENCODE consortium, has greatly improved our understanding of gene regulation. Therefore, the focus of this book is the description of the post-genome understanding of gene regulation."]