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[null,"1.","Record Nr.",null,"UNINA9910786241603321"]
[null,null,"Titolo",null,"Connexin cell communication channels : roles in the immune system and immunopathology / / edited by Ernesto Oviedo-Orta, Brenda R. Kwak, William Howard Evans"]
[null,null,"Pubbl/distr/stampa",null,"Boca Raton : , : Taylor & Francis/CRC Press, , 2013"]
[null,null,"ISBN",null,"0-429-16585-4"]
[{"$nulls":4},"1-4398-6258-3"]
[null,null,"Descrizione fisica",null,"1 online resource (363 p.)"]
[null,null,"Disciplina",null,"591.876041"]
[null,null,"Soggetti",null,"Gap junctions (Cell biology)"]
[{"$nulls":4},"Connexins"]
[{"$nulls":4},"Inflammation"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references."]
[null,null,"Nota di contenuto",null,"Front Cover; Contents; Preface; Editors; Contributors; Prequel: Gap Junctions, Hemichannels, and Cell-to-Cell Signalling; Chapter 1 - Communication in the Immune System by Connexin Channels; Chapter 2 - Gap Junctions and Connexins in the Hematopoietic-Immune System: Structural Considerations; Chapter 3 - Approaches for Studying the Role(s) of Gap Junctions in the Immune System; Chapter 4 - Gap Junctions in Antigen-Presenting Cells; Chapter 5 - Connect the Immune System: Roles of Gap Junctions in Antigen Presentation and T Cell Activation"]
[{"$nulls":4},"Chapter 6 - Gap Junctions and Connexins in the Immune Defense Against TumorsChapter 7 - Connexins in Atherosclerosis; Chapter 8 - Connexins in Lung Function and Inflammation; Chapter 9 - Effect of Oxidative Stress on Connexins in the Vasculature; Chapter 10 - Regulation of Gap Junctions and Cellular Coupling within the Microvasculature in Response to Acute Inflammation; Chapter 11 - Impact of Microglial Activation on Astroglial Connexin Expression and Function in Brain Inflammation; Chapter 12 - A Role for Connexins in Inflammatory Disorders of the Epidermis"]
[{"$nulls":4},"Chapter 13 - Translating Basic Research on Cx43 Gap Junctions into Therapies for Reducing Scarring and Cardiac ArrhythmiaChapter 14 - Connexin-Based Therapeutic Approaches to Inflammation in the Central Nervous System; Chapter 15 - Enhancing Epithelial Tissue "]
[{"$nulls":4},"Repair and Reducing Inflammation by Targeting Connexins; Back Cover"]
[null,null,null,"Sommario/riassunto","Plasma membrane-associated channels known as gap junctions, along with their protein building blocks-connexins-have an important functional role in a range of immunological processes, including heart function, cell growth and specialization, and early development. Spanning basic science and potential clinical applications, Connexin Cell Communication Channels: Roles in the Immune System and Immunopathology assembles and synthesizes four decades of the most important research carried out in this field. The book first provides a historical overview of the discovery of these membrane channels in"]