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[null,"1.","Record Nr.",null,"UNINA9910784526703321"]
[null,null,"Titolo",null,"Mouse development [[electronic resource] ] : patterning, morphogenesis, and organogenesis / / edited by Janet Rossant, Patrick P.L. Tam"]
[null,null,"Pubbl/distr/stampa",null,"San Diego, : Academic Press, c2002"]
[null,null,"ISBN",null,"1-281-05483-6"]
[{"$nulls":4},"9786611054830"]
[{"$nulls":4},"0-08-053703-0"]
[null,null,"Descrizione fisica",null,"1 online resource (731 p.)"]
[null,null,"Disciplina",null,"571.8/19353 22"]
[{"$nulls":4},"571.81935"]
[{"$nulls":4},"571.819353"]
[{"$nulls":4},"599.35163"]
[null,null,"Soggetti",null,"Mice - Development"]
[{"$nulls":4},"Mice - Physiology"]
[{"$nulls":4},"Mice as laboratory animals"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and indexes."]
[null,null,"Nota di contenuto",null,"Front Cover; Mouse Development: Patterning, Morphogenesis, and Organogenesis; Copyright Page; Contents; Contributors; About the Editors; Part I: Establishment of Body Patterns; Chapter 1. Fertilization and Activation of the Embryonic Genome; I. Introduction; II. Oogenesis; III. Meiosis and the Beginning of Oocyte Asymmetry; IV. Fertilization; V. Transcription andlts Control; VI. mRNA Utilization during Oocyte Maturation and Preimplantation Development; VII. Gene Expression in the Early Mouse Embryo; VIII. Functional Analysis; References"]
[{"$nulls":4},"Chapter 2. Asymmetry and Prepattern in Mammalian DevelopmentI. Introduction; II. Asymmetries in Early Development; III. Asymmetry of the Blastocyst; IV. Specification of the Polarity of the Anterior-Posterior Axis of the Fetus?; V. Conclusions; References; Chapter 3. Anterior Posterior Patterning of the Mouse Body Axis at Gastrulation; I. Introduction; II. Gastrulation; III. The Node: Morphogenesis, Cell Fate, and Cell Movement; IV. The Organizer Phenomenon: Conserved Properties of Vertebrate Organizers"]
[{"$nulls":4},"V. The Vertebrate Organizer is a Dynamic, Nonhomogeneous, and Renewable Cell Population at GastrulationVI. Insights into the Function "]
[{"$nulls":4},"of the Mouse Organizer Gained from Genetic and Embryological Studies; VII. Genetic Analysis of Organizer Function: Mouse Mutants Showing Defects in Organizer Function; VIII. Inhibitory Signals Secreted by the Organizer and Its Derivatives; IX. Specification of the Primitive Streak and the Organizer; X. Role of the AVE in Anterior Patterning in Mouse; XI. Embryological and Genetic Analysis of the Function of the AVE in Anterior Patterning"]
[{"$nulls":4},"XII. A Model for AVE Function in Anterior PatterningXIII. Conclusions and Future Directions; References; Chapter 4. Left-Right Asymmetry; I. Introduction; II. Morphological Left-Right Asymmetries; III. Genetic/Molecular Pathway Governing Left- Right Determination; IV. Molecular Readout of the First Asymmetry; V. Role of the Midline; VI. Readout of Left-Right Asymmetry in Later Development; VII. Miscellaneous Mutations/ Gene Factors; VIII. Diversity among Vertebrates; IX. Future Challenges; References; Chapter 5. Patterning, Regionalization, and Cell Differentiation in the Forebrain"]
[{"$nulls":4},"I. Organization of the ForebrainII. Early Patterning and Regional Specification of the Forebrain; III. Morphogenetic Mechanisms in the Forebrain; IV. Control of Neurogenesis and Cell-Type Specification in the Forebrain; References; Chapter 6. Establishment of Anterior-Posterior and Dorsal-Ventral Pattern in the Early Central Nervous System; I. Overview of Early CNS Development and Patterning; II. Anterior-Posterior Patterning of the Mesencephalon and Metencephalon; III. Hindbrain Anterior-Posterior Patterning Involves Segmental Units of Development"]
[{"$nulls":4},"IV. CNS Dorsal-Ventral Patterning Involves a Tug of War between Dorsal and Ventral Signaling"]
[null,null,null,"Sommario/riassunto","This book represents a classic compilation of current knowledge about mouse development and its correlates to research in cell biology, molecular biology, genetics, and neuroscience. Emphasis is placed on the research strategy, experimental design, and critical analysis of the data, disguishing this from other books that only focus on protocols for mouse developmental research. Selected chapters are indexed to electronic databases such as GeneBank, GenBank, Electronic Mouse Atlas, and Transgenic/Knockout, further increasing the utility of this book as a reference.*Broad-based overview"]