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[null,"1.","Record Nr.",null,"UNINA9910461389503321"]
[null,null,"Autore",null,"Lamb Chris <1958->"]
[null,null,"Titolo",null,"Conspiracy of silence [[electronic resource] ] : sportswriters and the long campaign to desegregate baseball / / Chris Lamb"]
[null,null,"Pubbl/distr/stampa",null,"Lincoln, : University of Nebraska Press, c2012"]
[null,null,"ISBN",null,"1-280-68765-7"]
[{"$nulls":4},"0-8032-4020-1"]
[{"$nulls":4},"9786613664594"]
[null,null,"Descrizione fisica",null,"1 online resource (414 p.)"]
[null,null,"Disciplina",null,"796.3570973"]
[null,null,"Soggetti",null,"Baseball - Social aspects - United States - History - 20th century"]
[{"$nulls":4},"Discrimination in sports - United States - History - 20th century"]
[{"$nulls":4},"Mass media and sports - United States - History - 20th century"]
[{"$nulls":4},"Sportswriters - United States - History - 20th century"]
[{"$nulls":4},"African American sportswriters - History - 20th century"]
[{"$nulls":4},"Racism - United States - History - 20th century"]
[{"$nulls":4},"Electronic books."]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Cover; Title page; Copyright Page; Contents; Acknowledgments; Part 1; Chapter 1: White Sportswriters and Minstrel Shows; Part 2; Chapter 2: The Color Line Is Drawn; Chapter 3: Invisible Men; Chapter 4: \"\"Agitators\"\" and \"\"Social-Minded Drum Beaters\"\"; Part 3; Chapter 5: \"\"L'Affaire Jake Powell\"\"; Chapter 6: Major League Managers and Ballplayers Call for End of Color Line; Part 4; Chapter 7: The Double V Campaign; Chapter 8: \"\"The Great White Father\"\" Speaks; Chapter 9: Black Editors Make Their Case for Desegregation; Chapter 10: \"\"Get Those Niggers Off the Field\"\"; Part 5"]
[{"$nulls":4},"Chapter 11: Robinson Becomes the Chosen One Part 6; Chapter 12: \"\"I never Want to Take Another Trip Like This One\"\"; Notes; Bibliography; Index"]
[null,null,null,"Sommario/riassunto","The campaign to desegregate baseball was one of the most important civil rights stories of the 1930's and 1940's. But most of white America knew nothing about this story because mainstream newspapers said little about the color line and less about the efforts to end it. Even today, as far as most Americans know, the integration of baseball "]
[{"$nulls":4},"revolved around Branch Rickey's signing of Jackie Robinson to the Brooklyn Dodgers' organization in 1945. This book shows how Rickey's move, critical as it may well have been, came after more than a decade of work by black and left-leaning journalists"]
[null,"2.","Record Nr.",null,"UNINA9910784504203321"]
[null,null,"Titolo",null,"Preclinical development handbook ADME and biopharmaceutical properties [[electronic resource] /] / [edited by] Shayne Cox Gad"]
[null,null,"Pubbl/distr/stampa",null,"Hoboken, N.J., : Wiley-Interscience, c2008"]
[null,null,"ISBN",null,"1-281-23741-8"]
[{"$nulls":4},"9786611237417"]
[{"$nulls":4},"0-470-24903-X"]
[{"$nulls":4},"0-470-24902-1"]
[null,null,"Descrizione fisica",null,"1 online resource (1347 p.)"]
[null,null,"Collana",null,"Pharmaceutical Development Series ; ; v.3"]
[null,null,"Disciplina",null,"615.1901"]
[{"$nulls":4},"615.7"]
[{"$nulls":4},"615/.7"]
[null,null,"Soggetti",null,"Pharmacokinetics"]
[{"$nulls":4},"Drug development"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"PRECLINICAL DEVELOPMENT HANDBOOK ADME and Biopharmaceutical Properties; CONTRIBUTORS; CONTENTS; Preface; 1 Modeling and Informatics in Drug Design; 2 Computer Techniques: Identifying Similarities Between Small Molecules; 3 Protein-Protein Interactions; 4 Method Development for Preclinical Bioanalytical Support; 5 Analytical Chemistry Methods: Developments and Validation; 6 Chemical and Physical Characterizations of Potential New Chemical Entity; 7 Permeability Assessment; 8 How and Where Are Drugs Absorbed?; 9 Absorption of Drugs after Oral Administration"]
[{"$nulls":4},"10 Distribution: Movement of Drugs through the Body11 The Blood-Brain Barrier and Its Effect on Absorption and Distribution; 12 Transporter Interactions in the ADME Pathway of Drugs; 13 Accumulation of Drugs in Tissues; 14 Salt and Cocrystal Form Selection; 15 Dissolution; 16 Stability: Physical and Chemical; 17 Dosage Formulation; 18 Cytochrome P450 Enzymes; 19 Metabolism Kinetics; 20 Drug Clearance; 21 In Vitro Metabolism in Preclinical Drug Development; 22 Utilization of In Vitro Cytochrome P450 Inhibition Data for Projecting Clinical Drug-Drug Interactions"]
[{"$nulls":4},"23 In Vivo Metabolism in Preclinical Drug Development24 In Vitro Evaluation of Metabolic Drug-Drug Interactions: Scientific Concepts and "]
[{"$nulls":4},"Practical Considerations; 25 Mechanisms and Consequences of Drug-Drug Interactions; 26 Species Comparison of Metabolism in Microsomes and Hepatocytes; 27 Metabolite Profiling and Structural Identification; 28 Linkage between Toxicology of Drugs and Metabolism; 29 Allometric Scaling; 30 Interrelationship between Pharmacokinetics and Metabolism; 31 Experimental Design Considerations in Pharmacokinetic Studies; 32 Bioavailability and Bioequivalence Studies"]
[{"$nulls":4},"33 Mass Balance Studies34 Pharmacodynamics; 35 Physiologically Based Pharmacokinetic Modeling; 36 Mathematical Modeling as a New Approach for Improving the Efficacy/Toxicity Profile of Drugs: The Thrombocytopenia Case Study; 37 Regulatory Requirements for INDs/FIH (First in Human) Studies; 38 Data Analysis; Index"]
[null,null,null,"Sommario/riassunto","A clear, straightforward resource to guide you through preclinical drug developmentFollowing this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic, comprehensive reference to prioritizing and optimizing leads, dose formulation, ADME, pharmacokinetics, modeling, and regulations. This authoritative, easy-to-use resource covers all the issues that need to be considered and provides detailed instructions for current methods and techniques.Each chapter is written by one or more leadin"]