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[null,"1.","Record Nr.",null,"UNINA9910457825703321"]
[null,null,"Titolo",null,"Neurologic complications of cancer therapy [[electronic resource] /] / [edited by] Patrick Y. Wen, David Schiff, Eudocia C. Quant"]
[null,null,"Pubbl/distr/stampa",null,"New York, : demos Medical, c2012"]
[null,null,"ISBN",null,"1-283-31755-9"]
[{"$nulls":4},"9786613317551"]
[{"$nulls":4},"1-61705-019-9"]
[null,null,"Descrizione fisica",null,"1 online resource (439 p.)"]
[null,null,"Disciplina",null,"616.99/406"]
[null,null,"Soggetti",null,"Cancer - Treatment - Complications"]
[{"$nulls":4},"Cancer - Treatment"]
[{"$nulls":4},"Neurologic manifestations of general diseases"]
[{"$nulls":4},"Electronic books."]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Neurologic complications of alkylating agent chemotherapy / Herbert B. Newton -- Neurologic complications of antimetabolites / Ryan Merrell, Jorg Dietrich, and Tracy Batchelor -- Neurologic complications associated with plant alkaloids / Abhishek Singla, Aditya Bardia, and Vinay Chaudhry -- Neurologic complications of topoisomerase inhibitors / April F. Eichler -- Neurologic complications of epothilones and amino acid degraders / April F. Eichler -- Neurologic complications of corticosteroids / Erin M Dunbar, Rizwan Kalani, and Santosh Kesari -- Neurologic complications of immunomodulatory agents / Stuart C. Apfel -- Neurologic complications of immunosuppressive drugs / Ramani Balu and Amy A.Pruitt -- Neurologic complications associated with biologic agents / Aaron G. Mammoser and Morris D. Groves -- Neurologic complications of targeted therapy / Eudocia C. Quant ... [et al.] -- Neurologic complications of hormonal chemotherapies / Wendy Sherman Sojka and Jeffrey Raizer -- Neurologic complications associated with supportive therapies / Jan Drappatz -- Chemotherapy-associated cognitive dysfunction / Jorg Dietrich and Alexander Pine -- Central nervous system toxicity of chemotherapy / Jerome J. Graber and Lisa M. DeAngelis -- Neurologic complications affecting peripheral nerves / Guido Cavaletti and Paola Marmiroli -- Neurologic complications affecting muscles and the neuromuscular junction / Kelly "]
[{"$nulls":4},"G. Gwathmey, Ted M. Burns, and Elliot L. Dimberg -- Cellular mechanisms of radiation injury to cognition / Michelle Monje -- Central nervous system complications of radiation therapy / Damien Ricard ... [et al.] -- Radiation-induced tumors / Hilary L. Somerset, B.K. Kleinschmidt-DeMasters, and Kevin O. Lillehei -- Radiation vasculopathy / Lisa R. Rogers -- Radiation myelopathy / Timothy E. Schultheiss -- Radiation-induced peripheral nerve disorders / Odysseas Kargiotis and Athanasios P. Kyritsis -- Complications of neurosurgical oncology / Brian J. Williams, Robert G. Louis, and Mark E. Shaffrey -- Neurologic complications of hematopoietic stem cell transplantation / Eudocia C. Quant and Patrick Y. Wen."]
[null,null,null,"Sommario/riassunto","Neurologic side effects of cancer therapy can inhibit treatment, can be dose-limiting and can diminish quality-of-life. Neurotoxicity related to cancer therapy is a common problem in oncology practice and in clinical neurology. Recognition of neurologic complications of anticancer therapy is necessary due to potential confusion with metastatic disease, paraneoplastic syndromes or comorbid neurologic disorders that do not require reduction or discontinuation of therapy. Neurologic Complications of Cancer Therapy provides comprehensive coverage of the recognition and management of neurologic sym"]
[null,"2.","Record Nr.",null,"UNINA9910780712703321"]
[null,null,"Titolo",null,"A guide to human gene therapy [[electronic resource] /] / editors, Roland W. Herzog, Sergei Zolotukhin"]
[null,null,"Pubbl/distr/stampa",null,"Singapore ; ; Hackensack, N.J., : World Scientific Pub. Co., 2010"]
[null,null,"ISBN",null,"1-283-14380-1"]
[{"$nulls":4},"9786613143808"]
[{"$nulls":4},"1-61344-779-5"]
[{"$nulls":4},"981-4280-91-7"]
[null,null,"Descrizione fisica",null,"1 online resource (416 p.)"]
[null,null,"Disciplina",null,"615.895"]
[null,null,"Soggetti",null,"Gene therapy"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Preface; Contents; Contributors; 1. Non-Viral Gene Therapy Sean M. Sullivan; 2. Adenoviral Vectors Stuart A. Nicklin and Andrew H. Baker; 3. Retroviral Vectors and Integration Analysis Cynthia C. Bartholomae, Romy Kirsten, Hanno Glimm, Manfred Schmidt and Christof von Kalle; 4. Lentiviral Vectors Janka Mátrai, Marinee K. L. Chuah and Thierry VandenDriessche; 5. Herpes Simplex Virus Vectors William F. Goins, David M. Krisky, James B. Wechuck, Darren Wolfe, Justus B. Cohen and Joseph C. Glorioso; 6. Adeno-Associated Viral (AAV) Vectors Nicholas Muzyczka"]
[{"$nulls":4},"7. Regulatory RNA in Gene Therapy Alfred. S. Lewin8. DNA Integrating Vectors (Transposon, Integrase) Lauren E. Woodard and Michele P. Calos; 9. Homologous Recombination and Targeted Gene Modification for Gene Therapy Matthew Porteus; 10. Gene Switches for Pre-Clinical Studies in Gene Therapy Caroline Le Guiner, Knut Stieger, Alice Toromanoff, Fabienne Rolling, Philippe Moullier and Oumeya Adjali; 11. Gene Therapy for Central Nervous System Disorders Deborah Young and Patricia A. Lawlor; 12. Gene Therapy of Hemoglobinopathies Angela E. Rivers and Arun Srivastava"]
[{"$nulls":4},"13. Gene Therapy for Primary Immunodeficiencies Aisha Sauer, Barbara Cassani and Alessandro Aiuti14. Gene Therapy for Hemophilia David Markusic, Babak Moghimi and Roland Herzog; 15. Gene Therapy for Obesity and Diabetes Sergei Zolotukhin and Clive H. Wasserfall; 16. Gene Therapy for Duchenne Muscular Dystrophy Takashi Okada and "]
[{"$nulls":4},"Shin'ichi Takeda; 17. Cancer Gene Therapy Kirsten A.K. Weigel-Van Aken; 18. Gene Therapy for Autoimmune Disorders Daniel F. Gaddy, Melanie A. Ruffner and Paul D. Robbins; 19. Gene Therapy for Inherited Metabolic Storage Diseases Cathryn Mah"]
[{"$nulls":4},"20. Retinal Diseases Shannon E. Boye, Sanford L. Boye and William W. Hauswirth21. A Brief Guide to Gene Therapy Treatments for Pulmonary Diseases Ashley T. Martino, Christian Mueller and Terence R. Flotte; 22. Cardiovascular Disease Darin J. Falk, Cathryn S. Mah and Barry J. Byrne; Index"]
[null,null,null,"Sommario/riassunto","Ever since the birth of molecular biology, the tantalizing possibility of treating disease at its genetic roots has become increasingly feasible. Gene therapy - though still in its infancy - remains one of the hottest areas of research in medicine. Its approach utilizes a gene transfer vehicle ( vector) to deliver therapeutic DNA or RNA to cells of the body in order to rectify the defect that is causing the disease. Successful therapies have been reported in humans in recent years such as cures in boys with severe immune deficiencies. Moreover, gene therapy strategies are being adapted in nume"]