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[null,"1.","Record Nr.",null,"UNINA9910780468403321"]
[null,null,"Titolo",null,"Thiol metabolism and redox regulation of cellular functions / / [edited by] Alfonso Pompella, Gabor Banhegyi, Maria Wellman-Rousseau"]
[null,null,"Pubbl/distr/stampa",null,"Amsterdam ; ; Washington, DC : , : IOS Press, , 2002"]
[null,null,"ISBN",null,"1-280-50567-2"]
[{"$nulls":4},"9786610505678"]
[{"$nulls":4},"600-00-0589-X"]
[{"$nulls":4},"1-60129-472-7"]
[null,null,"Descrizione fisica",null,"1 online resource (365 pages) : illustrations"]
[null,null,"Collana",null,"NATO science series. Series I, Life and behavioural sciences, , 1566-7693 ; ; v. 347"]
[null,null,"Disciplina",null,"572.7"]
[null,null,"Soggetti",null,"Antioxidants"]
[{"$nulls":4},"Thiols - Physiological effect"]
[{"$nulls":4},"Glutathione - Physiological effect"]
[{"$nulls":4},"Oxidation-reduction reaction"]
[{"$nulls":4},"Cell respiration"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","\"Published in cooperation with NATO Scientific Affairs Division.\""]
[{"$nulls":4},"\"Proceedings of the NATO Advanced Research Workshop on Thiol Metabolism and Redox Regulation of Cellular Functions, 10-13 April 2002, Pisa, Italy\"--T.p. verso."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Cover; Title page; Foreword; Preface; Contributors; Contents; Oxidative Signaling and Glutathione Synthesis; Cell Survival and Changes in Gene Expression in Cells Unable to Synthesize Glutathione; Role of Glutathione in the Regulation of Liver Metabolism; Glutathione Transport in the Endo/Sarcoplasmic Reticulum; Role of Ascorbate in Oxidative Protein Folding; Cytophotometric Investigations on Oscillating Thiol-Disulfide Equilibria and Oxidized Protein Sulfur; Protection by Pantothenic Acid against Apoptosis and Cell Damage by Oxygen Free Radicals - The Role of Glutathione"]
[{"$nulls":4},"Thiols as Major Determinants of the Total Antioxidant Capacity; Enzymes of the Thiol-dependent Hydroperoxide Metabolism in Pathogens as Potential Drug Targets; Is there a Role of Glutathione Peroxidases in Signaling and Differentiation?; Multidrug Resistance-associated Proteins: Export Pumps for Conjugates with Glutathione, Glucuronate or Sulfate; Detoxification of Electrophilic Compounds by "]
[{"$nulls":4},"Glutathione S-Transferase Catalysis: Determinants of Individual Response to Chemical Carcinogens and...; Transcriptional Regulation of Glutathione S-Transferase P1-1 in Human Leukemia"]
[{"$nulls":4},"Mechanism of γ-Glutamyltranspeptidase Folding and Activation in the Endoplasmic Reticulum; The Role of γ-Glutamyl Transpeptidase in the Biosynthesis of Glutathione; Role of γ-Glutamyltransferase in the Homeostasis of Glutathione during Oxidative and Nitrosative Stress; The Importance of gamma-Glutamyl Transferase in Lung Glutathione Homeostasis and Antioxidant Defense; The Role of gamma-Glutamyltranspeptidase in the Metabolism and Cytotoxicity of 4-Hydroxynonenal-Glutathione Conjugate: Evidence and Hypothesis; γ-Glutamyltransferase-Dependent Prooxidant Reactions: a Factor in Multiple Processes"]
[{"$nulls":4},"Serum gamma-Glutamyl Transpeptidase: a Prognostic Marker in Cardiovascular Diseases; Lipoic Acid: a Multifunctional Antioxidant; Is Glutathione an Important Neuroprotective Effector Molecule against Amyloid Beta Toxicity?; Antioxidants in Cancer Therapy: is there a Rationale to Recommend Antioxidants during Cancer Therapy?; Disulfide Exchange in CD4; Redox Regulation in Protein Folding and Chaperone Function; Reduction of the Endoplasmic Reticulum Accompanies the Oxidative Damage of Diabetes Mellitus; Analytical Developments in the Assay of Intra- and Extracellular GSH Homeostasis"]
[{"$nulls":4},"Signalling Potential and Protein Modifying Ability of Physiological Thiols; Redox Signaling and the Map Kinase Pathways; Redox Regulation of Mitochondrial Permeability Transition: Contrasting Effects of Lipoic Acid and its Positively Charged Analog LA-Plus; Redox State of Glutathione and Thioredoxin in Differentiation and Apoptosis; Redox Regulation of DNA Repair; Author Index"]
[null,null,null,"Sommario/riassunto","This volume contains contributions by some of the leading scientists in the field of thiol oxidation/reduction (redox) biochemistry. It is focused on the biological/pathophysiological implications of newly-discovered functions of cellular thiols, such as glutathione in the first place."]