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[null,"1.","Record Nr.",null,"UNINA9910780010503321"]
[null,null,"Titolo",null,"Standing operating procedures for developing acute exposure guideline levels for hazardous chemicals [[electronic resource] /] / Subcommittee on Acute Exposure Guideline Levels ...[et al.]"]
[null,null,"Pubbl/distr/stampa",null,"Washington ; ; [England], : National Academy Press, c2001"]
[null,null,"ISBN",null,"0-309-17086-9"]
[{"$nulls":4},"1-280-18464-7"]
[{"$nulls":4},"9786610184644"]
[{"$nulls":4},"0-309-57011-5"]
[null,null,"Descrizione fisica",null,"1 online resource (224 p.)"]
[null,null,"Disciplina",null,"363.1763"]
[null,null,"Soggetti",null,"Hazardous substances - Risk assessment - United States"]
[{"$nulls":4},"Chemicals - Physiological effect"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references."]
[null,null,"Nota di contenuto",null,"\"\"Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals\"\"; \"\"Copyright\"\"; \"\"Preface\"\"; \"\"Contents\"\"; \"\"Introduction\"\"; \"\"REVIEW OF THE NAC DOCUMENT\"\"; \"\"REFERENCES\"\"; \"\"Roster  National Advisory Committee for Acute Exposure Guideline Levels (NAC/AEGL Committee) for Hazardous Substances\"\"; \"\"COMMITTEE MEMBERS\"\"; \"\"Past Committee Members\"\"; \"\"Participants from Cooperative Partner Countries\"\"; \"\"Other Participants\"\"; \"\"Oak Ridge National Laboratory Staff\"\"; \"\"AEGL Program Senior Staff\"\"; \"\"Appendix\"\"; \"\"Preface\"\""]
[{"$nulls":4},"\"\"1. Overview of AEGL Program and NAC/AEGL Committee\"\"\"\"HISTORY\"\"; \"\"PURPOSE AND OBJECTIVES OF THE AEGL PROGRAM AND THE NAC/AEGL COMMITTEE\"\"; \"\"COMMITTEE MEMBERSHIP AND ORGANIZATIONAL STRUCTURE\"\"; \"\"SELECTION OF CHEMICALS FOR AEGL DEVELOPMENT\"\"; \"\"SCIENTIFIC CREDIBILITY OF AEGL VALUES\"\"; \"\"THE AEGL DEVELOPMENT AND PEER-REVIEW PROCESS\"\"; \"\"Stage 1: Draft AEGLs\"\"; \"\"Stage 2: Proposed AEGLs\"\"; \"\"Stage 3: Interim AEGLs\"\"; \"\"Stage 4: Final AEGLs\"\"; \"\"OPERATION OF THE NAC/AEGL COMMITTEE\"\"; \"\"VALUE OF A COLLABORATIVE EFFORT IN THE AEGL PROGRAM\"\"; \"\"APPLICATIONS OF THE AEGL VALUES\"\""]
[{"$nulls":4},"\"\"2. Derivation of AEGL Values\"\"\"\"2.1 CHARACTERIZATION OF AEGLS\"\"; \"\"2.2 EMPIRICAL TOXICOLOGIC ENDPOINTS AND METHODS FOR "]
[{"$nulls":4},"DETERMINING EXPOSURE CONCENTRATIONS USED TO DERIVE AEGLS 1, 2, AND 3\"\"; \"\"2.2.1 Selection of the Highest Exposure Level at Which the Effects That Define an AEGL Are Not Observed\"\"; \"\"2.2.2 Selection of Health-Effect Endpoints for AEGL-1, AEGL-2, and AEGL-3\"\"; \"\"2.2.2.1 AEGL-1 Endpoints\"\"; \"\"2.2.2.1.1 No Value Establishedâ€?AEGL-1 Is Close to or Exceeds AEGL-2\"\"; \"\"2.2.2.1.2 No Value Establishedâ€?Insufficient Data\"\""]
[{"$nulls":4},"\"\"2.2.2.1.3 Highest Experimental Exposure Without an AEGL-1 Effect\"\"\"\"2.2.2.1.4 Effect Level for a Response\"\"; \"\"2.2.2.2 AEGL-2 Endpoints\"\"; \"\"2.2.2.2.1 Highest Experimental Exposure Without an AEGL-2 Effect\"\"; \"\"2.2.2.2.2 Effect Level for a Toxic Response That Was Not Incapacitating or Not Irreversible\"\"; \"\"2.2.2.2.3 A Fraction of the AEGL-3 Value\"\"; \"\"2.2.2.3 AEGL-3 Endpoints\"\"; \"\"2.2.2.3.1 Highest Exposure Level That Does Not Cause Lethalityâ€?Experimentally Observed Threshold (AEGL-3 NOAEL)\"\""]
[{"$nulls":4},"\"\"2.2.2.3.2 Highest Exposure Level That Does Not Cause Lethalityâ€?Estimated Lethality Thresholdâ€?One-Third of the LC50\"\"\"\"2.2.2.3.3 Highest Exposure Level That Does Not Cause Lethalityâ€?Benchmark Exposure Calculation of the 5% and 1% Response\"\"; \"\"2.2.2.3.4 Effect Level for a Response\"\"; \"\"2.3 GUIDELINES AND CRITERIA FOR THE SEARCH STRATEGY, EVALUATION, SELECTION, AND DOCUMENTATION OF KEY DATA AND SUPPORTINGâ€?\"\"; \"\"2.3.1 Search Strategy\"\"; \"\"2.3.2 Evaluation, Selection, and Documentation of Key and Supporting Data\"\"; \"\"2.3.3 Elements for Discussion on Data Adequacy and Research Needs\"\""]
[{"$nulls":4},"\"\"2.4 DOSIMETRY CORRECTIONS FROM ANIMAL TO HUMAN EXPOSURES\"\""]