{"text_format":"2","workbook":"xls","n_sheets":1,"sheets":["report2"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":1,"defined_names":2,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"report2","index":0,"n_rows":44,"n_cols":5,"rows_kept":44,"cut":false,"hidden":false,"merged":[[0,2,0,3],[0,4,0,5],[1,2,1,3],[1,4,1,5],[2,2,2,3],[2,4,2,5],[3,2,3,3],[5,2,5,3],[8,2,8,3],[9,2,9,3],[10,2,10,3],[11,2,11,3],[14,2,14,3],[15,2,15,3],[18,2,18,3],[21,2,21,3],[21,4,21,5],[22,2,22,3],[22,4,22,5],[23,2,23,3],[23,4,23,5],[24,2,24,3],[25,2,25,3],[26,2,26,3],[27,2,27,3],[28,2,28,3],[29,2,29,3],[31,2,31,3],[38,2,38,3],[39,2,39,3],[41,2,41,3]],"flags":["formulas_cached_only"]}
[null,"1.","Record Nr.",null,"UNINA9910779402903321"]
[null,null,"Autore",null,"Heckman James J (James Joseph)"]
[null,null,"Titolo",null,"Giving kids a fair chance / / James J. Heckman"]
[null,null,"Pubbl/distr/stampa",null,"Cambridge, MA : , : The MIT Press, , [2013]"]
[{"$nulls":4},"©2013"]
[null,null,"ISBN",null,"0-262-31437-1"]
[{"$nulls":4},"1-299-44326-5"]
[{"$nulls":4},"0-262-31436-3"]
[null,null,"Descrizione fisica",null,"1 online resource (148 p.)"]
[null,null,"Collana",null,"Boston review books"]
[null,null,"Disciplina",null,"372.210973"]
[null,null,"Soggetti",null,"Children with social disabilities - Education (Early childhood) - United States"]
[{"$nulls":4},"Educational equalization - United States"]
[{"$nulls":4},"United States Social policy"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,"Nota di contenuto",null,"Contents; I Giving Kids a Fair Chance; II Forum; Mike Rose; Robin West; Charles Murray; Carol S. Dweck; David Deming; Neal McCluskey; Annette Lareau; Lelac Almagor; Adam Swift and Harry Brighouse; Geoffrey Canada; III Aiding the Life Cycle; About the Contributors; Boston Review Books"]
[null,null,null,"Sommario/riassunto","A top economist weighs in on one of the most urgent questions of our times: What is the source of inequality and what is the remedy?In Giving Kids a Fair Chance, Nobel Prize-winning economist James Heckman argues that the accident of birth is the greatest source of inequality in America today. Children born into disadvantage are, by the time they start kindergarten, already at risk of dropping out of school, teen pregnancy, crime, and a lifetime of low-wage work. This is bad for all those born into disadvantage and bad for American society.Current social and education policies directed toward children focus on improving cognition, yet success in life requires more than smarts. Heckman calls for a refocus of social policy toward early childhood interventions designed to enhance both cognitive abilities and such non-cognitive skills as confidence and perseverance. This new focus on preschool intervention would emphasize improving the early environments of disadvantaged children and increasing the quality of parenting while respecting the primacy of the family and America's "]
[{"$nulls":4},"cultural diversity. Heckman shows that acting early has much greater positive economic and social impact than later interventions--which range from reduced pupil-teacher ratios to adult literacy programs to expenditures on police--that draw the most attention in the public policy debate. At a time when state and local budgets for early interventions are being cut, Heckman issues an urgent call for action and offers some practical steps for how to design and pay for new programs.The debate that follows delves deeply into some of the most fraught questions of our time: the sources of inequality, the role of schools in solving social problems, and how to invest public resources most effectively. Mike Rose, Geoffrey Canada, Charles Murray, Carol Dweck, Annette Lareau, and other prominent experts participate."]
[null,"2.","Record Nr.",null,"UNINA9911018763903321"]
[null,null,"Autore",null,"Deng Wu-Min"]
[null,null,"Titolo",null,"The Drosophila Model in Cancer : Volume II / / edited by Wu-Min Deng, Cayetano Gonzaléz"]
[null,null,"Pubbl/distr/stampa",null,"Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2025"]
[null,null,"ISBN",null,"3-031-97035-7"]
[null,null,"Edizione",null,"[1st ed. 2025.]"]
[null,null,"Descrizione fisica",null,"1 online resource (492 pages)"]
[null,null,"Collana",null,"Advances in Experimental Medicine and Biology, , 2214-8019 ; ; 1482"]
[null,null,"Disciplina",null,"571.978"]
[{"$nulls":4},"616.994"]
[null,null,"Soggetti",null,"Cancer"]
[{"$nulls":4},"Cancer - Animal models"]
[{"$nulls":4},"Cancer - Genetic aspects"]
[{"$nulls":4},"Cancer Biology"]
[{"$nulls":4},"Cancer Models"]
[{"$nulls":4},"Cancer Genetics and Genomics"]
[{"$nulls":4},"Cancers"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,"Nota di contenuto",null,"Chapter 1. Unveiling the Tumor Suppressors: Insights from Drosophila -- Chapter 2. Notch signaling in Drosophila tumor models -- Chapter 3. Non-autonomous Regulation of Tumor Growth -- Chapter 4. Transcriptional Regulation of Lipid Metabolism by Wnt Signaling and Hox Protein Cues. - Chapter 5. The power of Drosophila in Modeling Cancer Cachexia -- Chapter 6. Drosophila Intestine as a Model to Study Tumors -- Chapter 7. Host-microbe Interactions in Drosophila Cancer -- Chapter 8. Drosophila as a Model for Metastasis -- Chapter 9. Epigenetic regulation in Drosophila Tumor Models -- Chapter 10. From the Making of a neural lineage to the Making of a Tumor: Lessons from the “simple” Drosophila Brain -- Chapter 11. Drosophila Melanogaster as a Model System for Human Glioblastoma -- Chapter 12. Translationally Controlled Tumor Protein (Tctp) and Growth Regulation in the Drosophila model -- Chapter 13. Modelling Cancer in Drosophila: Exploration to Personalised Medicine -- Chapter 14. SVC112; from hummingbirds to Head and Neck Cancer."]
[null,null,null,"Sommario/riassunto","This volume brings together a series of review articles that highlight new advances in using the fruit fly, Drosophila melanogaster, to study a "]
[{"$nulls":4},"wide range of cancer-related topics. Building on the foundation of Volume I, the articles demonstrate how research in Drosophila continues to uncover important developmental, cellular, and molecular mechanisms underlying tumor growth, progression, and systemic interactions. Readers will appreciate how the fly’s simple genetics and powerful experimental tools make it a flexible and effective model for studying cancer. Drosophila offers unique opportunities to answer key questions about how uncontrolled cell proliferation begins and progresses into cancer—questions that can be very difficult to explore in other systems. This book is a valuable resource for researchers interested in using the Drosophila model to better understand cancer biology and to help find new strategies to combat this disease."]