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[null,"1.","Record Nr.",null,"UNINA9910778938203321"]
[null,null,"Titolo",null,"Animal models for assessing countermeasures to bioterrorism agents [[electronic resource] /] / Committee on Animal Models for Assessing Countermeasures to Bioterrorism Agents"]
[null,null,"Pubbl/distr/stampa",null,"Washington, D.C., : National Academies Press, 2011"]
[null,null,"ISBN",null,"0-309-21912-4"]
[{"$nulls":4},"1-280-12326-5"]
[{"$nulls":4},"9786613527127"]
[{"$nulls":4},"0-309-21910-8"]
[null,null,"Descrizione fisica",null,"1 online resource (151 p.)"]
[null,null,"Disciplina",null,"570"]
[null,null,"Soggetti",null,"Bioterrorism"]
[{"$nulls":4},"Biology, Experimental"]
[{"$nulls":4},"Animal models in research"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references."]
[null,null,"Nota di contenuto",null,"\"\"Front matter\"\"; \"\"Acknowledgments\"\"; \"\"Contents\"\"; \"\"Summary\"\"; \"\"1  Introduction\"\"; \"\"2  Evaluation of Current and Future TMT-Used Animal Models\"\"; \"\"3  Ethical and Regulatory Challenges in the Development of Countermeasures\"\"; \"\"4  Developing New Animal Models for Biodefense Research\"\"; \"\"5  Alternative Approaches to Animal Testing for Biodefense Countermeasures\"\"; \"\"Appendix A:   The Animal Rule\"\"; \"\"Appendix B:   Draft Guidance for Industry\"\"; \"\"Appendix C:   Developing Animal Models for Use in Animal Rule Licensure: The NIAID Approach\"\"; \"\"Appendix D:   Presentations to the Committee\"\""]
[{"$nulls":4},"\"\"Appendix E:   Statement of Task\"\"\"\"Appendix F:   About the Authors\"\""]
[null,null,null,"Sommario/riassunto","\"The Transformational Medical Technologies (TMT) has been a unique component of the U.S. Department of Defense (DoD) medical biodefense efforts since 2006. Its mission is to advance countermeasure research and development in support of the broader goal of the DoD to protect warfighters from emerging infectious diseases and future genetically engineered biological weapons. The TMT, using advanced science and technology approaches, focused on the development of roadspectrum countermeasures that target common host and pathogen pathways or enhance the host's immune response. Many of these pathogens are lethal or cause such debilitating "]
[{"$nulls":4},"diseases in humans that it is ethically inappropriate to test the efficacy of these countermeasures in human volunteers. In lieu of human participants, these products may be tested in animals and approved for human use under the provisions of the Food and Drug Administration (FDA)'s 2002 Animal Rule. The reliance on animal models for the development and licensure of medical countermeasures against biothreats is challenging for a number of reasons.  The ad hoc Committee on Animal Models for Assessing Countermeasures to Bioterrorism Agents prepared a consensus report that would address the challenges stemming from developing and testing medical countermeasures against biothreat agents in animal models. Animal Models for Assessing Countermeasures to Bioterrorism Agents evaluates how well the existing TMT-employed or candidate animal models reflect the pathophysiology, clinical picture, and treatment of human disease as related to the agents of interest. The report addresses the process and/or feasibility of developing new animal models for critical biodefense research, placing emphasis on the need for a robust and expeditious validation process in terms of the FDA's Animal Rule. The report also evaluates alternatives to the use of animal models based on the premise of the Three Rs\"--Publisher's description."]
[null,"2.","Record Nr.",null,"UNINA9910255135803321"]
[null,null,"Autore",null,"Kember David"]
[null,null,"Titolo",null,"Understanding the Nature of Motivation and Motivating Students through Teaching and Learning in Higher Education / / by David Kember"]
[null,null,"Pubbl/distr/stampa",null,"Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2016"]
[null,null,"ISBN",null,"9789812878830"]
[{"$nulls":4},"9812878831"]
[null,null,"Edizione",null,"[1st ed. 2016.]"]
[null,null,"Descrizione fisica",null,"1 online resource (157 p.)"]
[null,null,"Disciplina",null,"370"]
[null,null,"Soggetti",null,"Education, Higher"]
[{"$nulls":4},"Learning, Psychology of"]
[{"$nulls":4},"Educational tests and measurements"]
[{"$nulls":4},"Higher Education"]
[{"$nulls":4},"Instructional Psychology"]
[{"$nulls":4},"Assessment and Testing"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,"Nota di contenuto",null,"Chapter 1 Studies -- Chapter 2 Motivation Framework -- Chapter 3 Relationship to other theories of motivation -- Chapter 4 Motivation to enrol -- Chapter 5 Motivation to study -- Chapter 6 Motivating students through teaching and learning -- Chapter 7 Motivating students through the curriculum -- Chapter 8 Systemic issues -- Chapter 9 Cultural and motivational issues concerning the performance of Chinese students -- Chapter 10 Reflections on motivation."]
[null,null,null,"Sommario/riassunto","This book is based upon three interrelated open naturalistic studies conducted to better characterise the motivational orientation of students in higher education. Open semi-structured individual interviews were conducted with undergraduates, students at community colleges and students in taught postgraduate courses in Hong Kong. The analysis used an exploratory grounded theory approach and resulted in a motivational orientation framework with six continua with positive and negative poles. On enrolment students had positions on the six facets of motivation, which shifted as they progressed through their degree according to their perceptions of the teaching and learning environment. The framework can, therefore, be used to explain both initial decisions to enrol and motivation to "]
[{"$nulls":4},"continue studying. The interviews included descriptions of teaching approaches and learning activities and their effects on motivation. This made it possible to describe a teaching and learning environment conducive to motivation, with eight supportive conditions. Each facet of the teaching and learning environment is illustrated with quotations from the three groups of students, resulting in a guide to configuring a teaching and learning environment conducive to motivating students. The emerging community-college sector in Hong Kong is used as a case study of the effects on student motivation of the expansion of the higher education sector through private colleges. Cultural issues are discussed, particularly the performance of Asian students relative to those in the West."]