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[null,"1.","Record Nr.",null,"UNINA9910778703803321"]
[null,null,"Titolo",null,"Modern methods of clinical investigation [[electronic resource] /] / Annetine C. Gelijns, editor ; Committee on Technological Innovation in Medicine, Institute of Medicine"]
[null,null,"Pubbl/distr/stampa",null,"Washington, D.C., : National Academy Press, 1990"]
[null,null,"ISBN",null,"1-280-21225-X"]
[{"$nulls":4},"9786610212255"]
[{"$nulls":4},"0-309-54356-8"]
[{"$nulls":4},"0-585-12524-4"]
[null,null,"Descrizione fisica",null,"1 online resource (244 p.)"]
[null,null,"Collana",null,"Medical innovation at the crossroads ; ; v. 1"]
[null,null,"Disciplina",null,"610/.72"]
[null,null,"Soggetti",null,"Medical technology - Evaluation"]
[{"$nulls":4},"Medical innovations - Evaluation"]
[{"$nulls":4},"Medical care - Technological innovations"]
[{"$nulls":4},"Meta-analysis"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Proceedings of a workshop held on May 3-4, 1989, supported by the Howard Hughes Medical Institute and the National Center for Health Services Research of the Department of Health and Human Services (grant 5 RO9 HS055 26 02)."]
[{"$nulls":4},"Includes index."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references."]
[null,null,"Nota di contenuto",null,"\"\"Modern Methods of Clinical Investigation\"\"; \"\"Copyright\"\"; \"\"Acknowledgments\"\"; \"\"Preface\"\"; \"\"Contents\"\"; \"\"List of Abbreviations\"\"; \"\"1 Medical Technology Development: An Introduction to the Innovation-Evaluation Nexus \"\"; \"\"PUTTING CLINICAL EVALUATION IN CONTEXT\"\"; \"\"ISSUES IN INNOVATION AND EVALUATION: THE CASE OF STABLE ANGINA PECTORIS\"\"; \"\"Beta-Blockers\"\"; \"\"Coronary Artery Bypass Grafting\"\"; \"\"PTCA Catheter Equipment\"\"; \"\"Evaluative Shortcomings in Technology Development\"\"; \"\"IMPROVING THE INNOVATION-EVALUATION NEXUS\"\"; \"\"The Selection of Endpoints in Evaluative Research\"\""]
[{"$nulls":4},"\"\"The Selection of Methods for Clinical Investigation\"\"\"\"Policy Mechanisms for Improving Developmental Decision Making\"\"; \"\"REFERENCES\"\"; \"\"2 The Selection of Endpoints in Evaluative Research \"\"; \"\"SURROGATE VERSUS CLINICAL ENDPOINTS\"\"; \"\"CLINICAL ENDPOINTS\"\"; \"\"SURROGATE ENDPOINTS\"\"; \"\"REFERENCES\"\"; \"\"3 "]
[{"$nulls":4},"Advances in Health Status Measurement: The Potential to Improve Experimental and Non-Experimental Data Collection\"\"; \"\"THE CONDUCT OF CLINICAL TRIALS\"\"; \"\"MEASUREMENT OF QUALITY OF LIFE AND OF HEALTH STATUS\"\"; \"\"INCLUSION OF QUALITY OF LIFE AND HEALTH STATUS MEASURES IN CLINICAL TRIALS\"\""]
[{"$nulls":4},"\"\"FOUR PROBLEMS REGARDING THE MEASUREMENT OF HEALTH STATUS IN CLINICAL TRIALS\"\"\"\"REFERENCES\"\"; \"\"4 What Is Outcomes Research? \"\"; \"\"WHICH RATE IS RIGHT?\"\"; \"\"ENGAGING PATIENTS IN THE DECISION PROCESS\"\"; \"\"EXTENDING ASSESSMENT TO ALL RELEVANT TREATMENT THEORIES\"\"; \"\"THE EVALUATIVE CLINICAL SCIENCES AND THE FUTURE OF MEDICINE\"\"; \"\"REFERENCES\"\"; \"\"5 Strengths and Weaknesses of Health Insurance Data Systems for Assessing Outcomes\"\"; \"\"STRENGTHS\"\"; \"\"System-Wide, Population-Based Data\"\"; \"\"Efficacy versus Effectiveness\"\"; \"\"Large Numbers and Time Series\"\"; \"\"Events Unaffected by Recall\"\""]
[{"$nulls":4},"\"\"Unobtrusive Nature\"\"\"\"Multiple Comparisons\"\"; \"\"Design Flexibility\"\"; \"\"Potential for Multiple Projects\"\"; \"\"Focus on Risks\"\"; \"\"Clinical Decision Making\"\"; \"\"WEAKNESSES\"\"; \"\"Structural Limitations\"\"; \"\"Bias Due to Reporting and Coding\"\"; \"\"Bias Due to Differential Contact\"\"; \"\"Benefits of Treatment\"\"; \"\"CONTROVERSIAL AREAS\"\"; \"\"Risk Adjustment\"\"; \"\"Outcome Measures\"\"; \"\"EXPANDING DATA BASES\"\"; \"\"Record Linkage\"\"; \"\"Primary Data Collection\"\"; \"\"DISCUSSION\"\"; \"\"REFERENCES\"\"; \"\"6 Prescription-Event Monitoring: An Example of Total Population Post-Marketing Drug Surveillance \"\""]
[{"$nulls":4},"\"\"\"\"THE NUMBERS GAME\"\"\"\"\"\"VOLUNTARY REPORTING SYSTEMS\"\"; \"\"POST-MARKETING SURVEILLANCE\"\"; \"\"PRESCRIPTION-EVENT MONITORING\"\"; \"\"COMPARATIVE STUDIES OF NSAIDS\"\"; \"\"POST-MARKETING SURVEILLANCE AND POST-MARKETING CLINICAL TRIALS\"\"; \"\"CONCLUSION\"\"; \"\"REFERENCES\"\"; \"\"7 The Role of Decision Analysis in the Translation of Research Findings into Clinical Practice \"\"; \"\"DECISION ANALYSIS AT THE INTERFACE BETWEEN CLINICAL INVESTIGATION AND CLINICAL PRACTICE\"\"; \"\"WHAT DECISION ANALYSIS IS\"\"; \"\"THE LIMITATIONS OF DECISION ANALYSIS: WHAT IT IS NOT\"\""]
[{"$nulls":4},"\"\"SETTING PRIORITIES AND PARAMETERS FOR CLINICAL INVESTIGATION\"\""]