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[null,"1.","Record Nr.",null,"UNINA9910779124703321"]
[null,null,"Autore",null,"Shepherd Dean A"]
[null,null,"Titolo",null,"Attracting equity investors [[electronic resource] ] : positioning, preparing, and presenting the business plan / / Dean A. Shepherd, Evan J. Douglas"]
[null,null,"Pubbl/distr/stampa",null,"Thousand Oaks, Calif. ; ; London, : SAGE, 1999"]
[null,null,"ISBN",null,"1-322-41541-2"]
[{"$nulls":4},"0-7619-1476-5"]
[{"$nulls":4},"1-4522-6254-3"]
[null,null,"Descrizione fisica",null,"1 online resource (xviii, 174 p.)"]
[null,null,"Collana",null,"Entrepreneurship and the management of growing enterprises"]
[null,null,"Disciplina",null,"658.15224"]
[null,null,"Soggetti",null,"Business enterprises - Finance"]
[{"$nulls":4},"Capitalists and financiers"]
[{"$nulls":4},"Business planning"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Cover; Contents; List of Tables and Figures; Acknowledgments; Introduction; Chapter 1 - Sources of Early-Stage Financing; Chapter 2 - Roles and Equity Shares in the New Venture; Chapter 3 - Evaluate the Business from the Investor's Perspective; Chapter 4 - Evaluate the Managers from the Investor's Perspective; Chapter 5 - The Three-Stage Communication Strategy; Chapter 6 - Write a Compelling Business Plan; Chapter 7 - Successfully Presenting and Defending Your Business Plan; Chapter 8 - Valuing the Business and Negotiating the Deal; Chapter 9 - Summary and Conclusions; Index"]
[{"$nulls":4},"About the Authors"]
[null,null,null,"Sommario/riassunto","Attracting Equity Investors is an invaluable guide to obtaining funding from an investor for the creation or development of a new business venture."]
[null,"2.","Record Nr.",null,"UNINA9910754089903321"]
[null,null,"Autore",null,"Langel Ülo"]
[null,null,"Titolo",null,"CPP, Cell-Penetrating Peptides / / by Ülo Langel"]
[null,null,"Pubbl/distr/stampa",null,"Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023"]
[null,null,"ISBN",null,"9783031387319"]
[{"$nulls":4},"9783031387302"]
[null,null,"Edizione",null,"[2nd ed. 2023.]"]
[null,null,"Descrizione fisica",null,"1 online resource (564 pages)"]
[null,null,"Disciplina",null,"572.65"]
[null,null,"Soggetti",null,"Drug delivery systems"]
[{"$nulls":4},"Proteins"]
[{"$nulls":4},"Pharmacology"]
[{"$nulls":4},"Pharmaceutical chemistry"]
[{"$nulls":4},"Biomaterials"]
[{"$nulls":4},"Drug Delivery"]
[{"$nulls":4},"Protein Biochemistry"]
[{"$nulls":4},"Medicinal Chemistry"]
[{"$nulls":4},"Biomaterials-Proteins"]
[{"$nulls":4},"Proteòmica"]
[{"$nulls":4},"Medicaments peptídics"]
[{"$nulls":4},"Llibres electrònics"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,"Nota di contenuto",null,"1. Introduction -- 2. Classes and applications of CPP -- 3. CPP selection, prediction and in silico analysis -- 4. Labeling of CPPs -- 5. Methods for CPP functionalization with oligonucleotides -- 6. Additional (gene therapeutic) platforms -- 7. Protein delivery and mimicry -- 8. General targeting strategies -- 9. Targeting specific barriers -- 10. Methods for molecular imaging, detection and visualization of CPPs -- 11. Methods for structural studies of CPPs -- 12. Kinetics -- 13. Toxicity and immune response -- 14. Cell-translocation mechanisms of CPPs -- 15. Clinical trials and commercialization using CPPs -- 16. Therapeutic potential of CPPs -- 17. CPP functionalized nanoparticles -- 18. Concluding remarks."]
[null,null,null,"Sommario/riassunto","In this book, a summary and update of the most important areas of cell-penetrating peptides (CPP) research are presented, while raising "]
[{"$nulls":4},"relevant questions for further development. The CPP sequences are presented and discussed throughout the book. The methods for testing CPP mechanisms are discussed in detail. Various approaches for the testing of endocytotic pathways of CPP uptake are also described. Different CPP uptake experiments are compared since it is becoming clear that it is often best to apply several methods in a complementary manner in order to most comprehensively evaluate CPP uptake mechanisms due to the complexity of these processes. A brief summary of functionality issues of CPPs, both in vitro and in vivo, is discussed. Therapeutic potential of CPPs and commercial developments are discussed. The present, second edition of this book is the updated and expanded version of the first edition, published in 2019. The development of the field of cell-penetrating peptides in these five years has been obvious and exciting. This second edition of the book has been partly reorganized and comprehensively expanded with the exciting research in 2019-2023. Around 2500 novel scientific articles have become available, most of them are reviewed in the second edition. Additional rapidly growing areas of high impact presented in this second edition are therapeutic developments (Chapter 16) and delivery of oligonucleotides and proteins/peptides (Chapters 5 and 6) including novel reports on genome editing with CPP assistance. Also, several additional examples are available now on clinical trials using CPPs (Chapter 15). The book is written for researchers and students in the field."]