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[null,"1.","Record Nr.",null,"UNINA9910692053703321"]
[null,null,"Autore",null,"Ford Jess T"]
[null,null,"Titolo",null,"Border security [[electronic resource] ] : new policies and procedures are needed to fill gaps in the visa revocation process : statement of Jess T. Ford before the Subcommittee on National Security, Emerging Threats, and International Relations, Committee on Government Reform, House of Representatives"]
[null,null,"Pubbl/distr/stampa",null,"[Washington, D.C.] : , : U.S. General Accounting Office, , [2003]"]
[null,null,"Collana",null,"Testimony ; ; GAO-03-908 T"]
[null,null,"Soggetti",null,"Visas - United States"]
[{"$nulls":4},"Emigration and immigration law - United States"]
[{"$nulls":4},"National security - Law and legislation - United States"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Title from title screen (viewed on Aug. 27, 2003)."]
[{"$nulls":4},"\"For release ... June 18, 2003.\""]
[{"$nulls":4},"Paper version available from: General Accounting Office, 441 G St., NW, Rm. LM, Washington, D.C. 20548."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references."]
[null,"2.","Record Nr.",null,"UNINA9910813135703321"]
[null,null,"Titolo",null,"Genome organization and function in the cell nucleus / / edited by Karsten Rippe"]
[null,null,"Pubbl/distr/stampa",null,"Heidelberg, Germany, : Wiley-VCH, c2012"]
[null,null,"ISBN",null,"9783527640003"]
[{"$nulls":4},"3527640002"]
[{"$nulls":4},"9781283869904"]
[{"$nulls":4},"128386990X"]
[{"$nulls":4},"9783527640010"]
[{"$nulls":4},"3527640010"]
[{"$nulls":4},"9783527639991"]
[{"$nulls":4},"3527639993"]
[null,null,"Edizione",null,"[1st ed.]"]
[null,null,"Descrizione fisica",null,"1 online resource (596 p.)"]
[null,null,"Classificazione",null,"WE 4000"]
[{"$nulls":4},"570"]
[{"$nulls":4},"QU 350"]
[null,null,"Disciplina",null,"572.8619"]
[null,null,"Soggetti",null,"Mammals - Genetics"]
[{"$nulls":4},"Genomes"]
[{"$nulls":4},"Molecular genetics"]
[{"$nulls":4},"Aufsatzsammlung"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Genome Organization and Function in the Cell Nucleus; Contents; Preface; List of Contributors; 1: Deciphering DNA Sequence Information; 1.1: Introduction; 1.2: Genes and Transcribed Regions; 1.2.1: Open Reading Frames; 1.2.2: Mapping Transcriptional Start Sites; 1.2.3: Mapping Untranslated Regions on mRNA; 1.3: Non-Coding Genomic Elements; 1.3.1: Pseudogenes; 1.3.2: Repeats; 1.3.3: Structural Variants; 1.3.4: Methods for SV Detection; 1.3.5: Transposons and Retrotransposons; 1.4: Regulatory Information; 1.4.1: Classes of Regulatory Elements; 1.4.2: Transcription Factor Binding Motifs"]
[{"$nulls":4},"1.4.3: Allele-Specific Expression1.5: Individual Genetic Polymorphisms and Their Effect on Gene Expression; 1.6: Conclusion; 2: DNA Methylation; 2.1: Introduction; 2.1.1: Discovery of 5-Methylcytosine in "]
[{"$nulls":4},"DNA; 2.1.2: Epigenetic Control of Gene Expression; 2.2: Eukaryotic DNA Methyltransferases; 2.2.1: Dnmt1; 2.2.2: The Dnmt3 Family; 2.2.3: Cooperative Function of Dnmts; 2.3: Distribution of 5-Methylcytosine in the Mammalian Genome; 2.3.1: Spatial Distribution of 5-Methylcytosine; 2.3.2: CpG Islands and Promoter Regulation; 2.3.3: Repetitive DNA Sequences"]
[{"$nulls":4},"2.3.4: Temporal Distribution of 5-Methylcytosine2.4: Control of Gene Expression by DNA Methylation; 2.4.1: Loss of Transcription Factor Binding; 2.4.2: Methyl-CpG Binding Proteins; 2.4.3: Interconnection of DNA Methylation with Other Epigenetic Pathways; 2.4.4: DNA Methylation, Higher Order Chromatin Structure, and Nuclear Architecture; 2.5: DNA Demethylation; 3: Nucleosomes as Control Elements for Accessing the Genome; 3.1: Introduction and Basic Terminology; 3.2: Nucleosomes are the Building Blocks of Chromatin; 3.2.1: Histones; 3.2.2: Protein DNA Interactions in the Nucleosome"]
[{"$nulls":4},"3.2.3: The Structure of Nucleosomal DNA3.3: Nucleosomes Are Dynamic Macromolecular Assemblies; 3.3.1: Mechanisms to Promote Histone Exchange In Vivo; 3.3.2: In Vitro Determination of Nucleosome Stability; 3.4: Histone Variants and Their Effect on Nucleosome Structure and Dynamics; 3.4.1: Variant Nucleosome Structures; 3.5: Histone Modifications in Nucleosome and Chromatin Structure; 3.6: DNA Sequence and Nucleosome Positioning; 3.6.1: Mechanisms for Nucleosome Exclusion; 3.6.2: Features that Promote Nucleosome Formation; 3.7: Histone Chaperones and Chromatin Dynamics; 3.7.1: Transcription"]
[{"$nulls":4},"3.7.2: DNA Replication3.7.3: DNA Repair; 3.7.4: Mechanism of Chaperone-Mediated Nucleosome Assembly and Disassembly; 3.8: Outlook and Concluding Remarks; 4: Histone Modifications and Their Role as Epigenetic Marks; 4.1: The Complexity of Histone Modifications; 4.2: Regulating Histone Modifications in Chromatin; 4.3: The \"\"Histone Code\"\" Hypothesis; 4.3.1: Defining Histone \"\"Marks.\"\" Why Is Histone Modification so Complex?; 4.3.2: Recognizing Histone Modifications: \"\"Reader\"\" Domains; 4.4: Exploiting the Complexity of the Histone Code: \"\"Crosstalk\"\" Between Different Modifications"]
[{"$nulls":4},"4.4.1: Histone \"\"Crosstalk\"\": Increased Code Complexity and Signal Integration"]
[null,null,null,"Sommario/riassunto","By way of its clear and logical structure, as well as abundant highresolution illustrations, this is a systematic survey of the players and pathways that control genome function in the mammalian cell nucleus. As such, this handbook and reference ties together recently gainedknowledge from a variety of scientific disciplines and approaches, dissecting all major genomic events: transcription, replication, repair,recombination and chromosome segregation. A special emphasis is put on transcriptional control, including genome-wide interactions andnon-coding RNAs, chromatin structure, ep"]