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[null,"1.","Record Nr.",null,"UNINA9910674386903321"]
[null,null,"Autore",null,"Manini Claudia"]
[null,null,"Titolo",null,"Clear Cell Renal Cell Carcinoma 2021-2022 / / Claudia Manini and José I. López"]
[null,null,"Pubbl/distr/stampa",null,"Basel, Switzerland : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2022"]
[null,null,"Descrizione fisica",null,"1 online resource (342 pages)"]
[null,null,"Disciplina",null,"616.99461"]
[null,null,"Soggetti",null,"Biomedical materials"]
[{"$nulls":4},"Carcinoma, Renal Cell"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Sommario/riassunto","Clear cell renal cell carcinoma is currently one of the most interesting areas of study in oncology. Despite the advances made in this field, this tumor continues to be a health problem of major concern in Western societies, seriously affecting public health services. Several characteristics of this tumor make it an exciting meeting point for translational collaboration between clinicians and basic researchers. Clear cell renal cell carcinoma is a paradigmatic example of inter- and intra-tumor heterogeneity from morphological, immunohistochemical, and molecular viewpoints. This tumor is also a good example to investigate the complexity of tumor/tumor and tumor/environment relationships from an ecological perspective. A deeper identification of the varied internal tumor self-organization through the specialization of cell clones and subclones as local invaders and metastasizers, on one hand, and the interactions of specific subsets of tumor cells with the local host microenvironment, on the other, will significantly enrich our knowledge of this neoplasm. Clear cell renal cell carcinoma is also a paradigmatic test bench for antiangiogenic and immune checkpoint blockage therapies. The refinement of these therapeutic tools administered alone or in combination is a hot issue in oncology, and several international trials are underway."]
[null,"2.","Record Nr.",null,"UNINA9910158892603321"]
[null,null,"Autore",null,"Tony Husband"]
[null,null,"Titolo",null,"Dictators in cartoons"]
[null,null,"Pubbl/distr/stampa",null,"Arcturus"]
[null,null,"ISBN",null,"1-78428-184-0"]
[null,null,"Descrizione fisica",null,"1 online resource (1 p.)"]
[null,null,"Disciplina",null,"741.569"]
[null,null,"Soggetti",null,"Dictators"]
[{"$nulls":4},"History, Modern"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Sommario/riassunto","What is it that makes dictators fear cartoonists? The answer is that they can't stand to be ridiculed. And they don't help their cause much by so obviously enjoying the trappings of power, appearing in public with a retinue of bodyguards, a fleet of limousines and rows of medals across their chests topped off with over-sized sunglasses. Cartoonists may not be able to topple tyrants or change the course of history, but they can lessen the climate of fear and bring courage to the victims of state bullying with their subversive drawings. Laughter is the last thing dictators want to hear, especially when they are the subject of it."]