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[null,"1.","Record Nr.",null,"UNINA990010026350403321"]
[null,null,"Autore",null,"Darby, Paul"]
[null,null,"Titolo",null,"Africa football and FIFA : politics, colonialism, and resistance / Paul Darby"]
[null,null,"Pubbl/distr/stampa",null,"London ; Portland, OR : Frank Cass, 2002"]
[null,null,"Descrizione fisica",null,"XVI, 236 p. ; 25 cm"]
[null,null,"Collana",null,"Sport in the global society"]
[null,null,"Disciplina",null,"306.483"]
[null,null,"Locazione",null,"BFS"]
[null,null,"Collocazione",null,"306.483 DAR 1"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,"2.","Record Nr.",null,"UNINA9910619465503321"]
[null,null,"Autore",null,"Allison Simon J"]
[null,null,"Titolo",null,"Novel Anti-cancer Agents and Cellular Targets and Their Mechanism(s) of Action"]
[null,null,"Pubbl/distr/stampa",null,"MDPI - Multidisciplinary Digital Publishing Institute, 2022"]
[null,null,"ISBN",null,"3-0365-5222-7"]
[null,null,"Descrizione fisica",null,"1 online resource (206 p.)"]
[null,null,"Soggetti",null,"History of engineering & technology"]
[{"$nulls":4},"Technology: general issues"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Sommario/riassunto","Patient outcomes remain poor for many cancers despite improvements in treatments and new molecular-targeted biomedicines for certain cancer types or subtypes. Dose-limiting toxicity, a narrow therapeutic index, and the development of resistance to traditional anti-cancer agents are well-established. It is apparent that inherent and acquired drug resistance are major challenges with molecular-targeted agents and that on- as well as off-target side effects can still occur. Other issues include drug metabolism by the body and safely supplying a sufficient amount of active drug to the tumor cells. There is a clear and urgent need for new molecular targets and drugs that specifically target cancer cells in different ways to existing approved drugs. This book, through a collection of eight research articles and two review articles from the Biomedicines themed Special Issue 'Novel Anti-Cancer Agents and Cellular Targets and Their Mechanism(s) of Action', provides a snapshot of some of the diverse and exciting research approaches being taken by the cancer research community in trying to address some of these therapeutic challenges."]