{"text_format":"2","workbook":"xls","n_sheets":1,"sheets":["report2"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":1,"defined_names":2,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"report2","index":0,"n_rows":37,"n_cols":5,"rows_kept":37,"cut":false,"hidden":false,"merged":[[0,2,0,3],[0,4,0,5],[1,2,1,3],[1,4,1,5],[2,2,2,3],[2,4,2,5],[3,2,3,3],[4,2,4,3],[5,2,5,3],[7,2,7,3],[8,2,8,3],[11,2,11,3],[11,4,11,5],[12,2,12,3],[12,4,12,5],[13,2,13,3],[13,4,13,5],[14,2,14,3],[15,2,15,3],[17,2,17,3],[18,2,18,3],[19,2,19,3],[21,2,21,3],[32,2,32,3],[33,2,33,3],[35,2,35,3]],"flags":["formulas_cached_only"]}
[null,"1.","Record Nr.",null,"UNINA9910576878603321"]
[null,null,"Autore",null,"Pulliero Alessandra"]
[null,null,"Titolo",null,"Role of MicroRNA in Cancer Development and Treatment"]
[null,null,"Pubbl/distr/stampa",null,"Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022"]
[null,null,"Descrizione fisica",null,"1 online resource (280 p.)"]
[null,null,"Soggetti",null,"Medicine and Nursing"]
[{"$nulls":4},"Pharmacology"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Sommario/riassunto","Many researchers around the world have demonstrated that the expression of miRNAs is dysregulated in different tumors. Such dysregulation is caused by multiple mechanisms, and exposure to different carcinogens causes dysregulated epigenetic changes and defects in the miRNA biogenesis machinery. Cancer cells with abnormal miRNA expression evolve the capability to sustain proliferative signaling, evade growth suppressors, resist cell death, activate invasion and metastasis, and induce angiogenesis. Genome-wide profiling demonstrates that miRNA expression signatures are associated with tumor type, tumor grade and clinical outcomes, so miRNAs could be potential candidates for diagnostic biomarkers, prognostic biomarkers, therapeutic targets and preventive screening programs. Although miRNAs have multiple targets, their function in tumorigenesis is due to their regulation of a few specific targets. After the first detection of altered miRNA in leukemia, microRNAs have been demonstrated to be constantly altered in all cancer. More recently, microRNA has been shown to be altered by exposure to environmental carcinogens, thus driving the whole process of carcinogenesis. Our aim is to provide a rigorous peer review and publish cutting-edge research on the role of microRNA in cancer prevention therapy to educate and inspire the scientific community worldwide."]
[null,"2.","Record Nr.",null,"UNINA9910616395603321"]
[null,null,"Autore",null,"Sanchez Alexandra J."]
[null,null,"Titolo",null,"Discourses of Migration in Documentary Film : Translating the Real to the Reel / / by Alexandra J. Sanchez"]
[null,null,"Pubbl/distr/stampa",null,"Cham : , : Springer International Publishing : , : Imprint : Palgrave Macmillan, , 2022"]
[null,null,"ISBN",null,"9783031065392"]
[{"$nulls":4},"9783031065385"]
[null,null,"Edizione",null,"[1st ed. 2022.]"]
[null,null,"Descrizione fisica",null,"1 online resource (290 pages)"]
[null,null,"Disciplina",null,"070.18"]
[{"$nulls":4},"791.436552"]
[null,null,"Soggetti",null,"Translating and interpreting"]
[{"$nulls":4},"Documentary films"]
[{"$nulls":4},"Motion pictures"]
[{"$nulls":4},"Television broadcasting"]
[{"$nulls":4},"Communication"]
[{"$nulls":4},"Culture - Study and teaching"]
[{"$nulls":4},"Language Translation"]
[{"$nulls":4},"Documentary Studies"]
[{"$nulls":4},"Film and Television Studies"]
[{"$nulls":4},"Media and Communication"]
[{"$nulls":4},"Cultural Studies"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,"Nota di contenuto",null,"Chapter 1: Introduction -- Chapter 2: Documentary Makers as Translators -- Chapter 3: Translating Migration through the Lens of Motherhood -- Chapter 4: Translating Migration through the Lens of Fatherhood -- Chapter 5: Translating Migration through the Lens of Childhood -- Chapter 6: Translating Migration through the Lens of Citizenship -- Chapter 7: Translating Migration through the Lens of Biculturalism -- Chapter 8: Translating Migration through the Lens of Criminality -- Chapter 9: Translating Migration through the Lens of Queerness -- Chapter 10: Translating Migration through the Lens of Adoption -- Chapter 11: Translating Migration through the Lens of Fame -- Chapter 12: Documentary Practices as Translation Strategies and Tactics -- Chapter 13: Conclusion."]
[null,null,null,"Sommario/riassunto","“This book is a carefully developed and methodologically interesting effort to map the intersection of three fields: documentary studies, translation studies, and discourse analysis. For Sanchez, the documentarist is a cultural translator negotiating the difference between the reality of migrants and migration, and the forms of representation that can be most effective in the target culture. Four aspects of translation (contexts, agents, practices, and discourses) guide her study in positive discourse analysis, i.e. the exploration of the fluid and potentially empowering space between the mainstream and dissenting voices.” —Juan Poblete, University of California Santa Cruz, USA “In the era of global migration, this timely study make a significant contribution to the interdisciplinary study of documentary film addressing Latinx mobilities in the US. Combining Translation Studies and Cultural Studies, the impressive volume provides insightful readings of how migrants’ lives and concerns are addressed in the work of independent filmmakers. It is essential reading to both researchers and practitioners in the field.” —Jopi Nyman, University of Eastern Finland, Finland “Both captivating and urgent, this work offers a fresh perspective on Latinx migration. It demonstrates how independent documentary films translate real-life discourses about migration, family, citizenship and culture.” —Kevin Smets, Vrije Universiteit Brussel, Belgium This book proposes a new, translational approach to the study of discourse in documentary film. It considers discourse as a basic factor of translation (as well as contexts, agents, and practices) and draws on the parallels between the disciplines of translating and documentary making to perform a discourse analysis of documentaries centering on migration. More specifically, the book uses the concept of translation as a heuristic tool to highlight the discursive mechanisms of 18 documentaries on Latin American migration showcased over the last 30 years in the United States by the Public Broadcasting Service series POV. This innovative, interdisciplinary methodology facilitates a holistic analysis of documentary film discourse, while also raising awareness of positive discourses of migration. Alexandra J. Sanchez is a Research Fellow at KU Leuven, Belgium. ."]