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[null,"1.","Record Nr.",null,"UNINA990001444130403321"]
[null,null,"Autore",null,"Kittel, Charles"]
[null,null,"Titolo",null,"Meccanica / Charles Kittel, Walter D. Knight, Malvin A. Ruderman ; traduzione di Donatello Canalini ... [et al. ]"]
[null,null,"Pubbl/distr/stampa",null,"Bologna : Zanichelli, ©1970"]
[null,null,"ISBN",null,"88-08-01272-7"]
[null,null,"Descrizione fisica",null,"xxiv, 500 p. : ill. ; 24 cm"]
[null,null,"Disciplina",null,"530"]
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[null,null,"Lingua di pubblicazione",null,"Italiano"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,"2.","Record Nr.",null,"UNINA9910598027503321"]
[null,null,"Titolo",null,"Grand Celebration : 10th Anniversary of the Human Genome Project / / MDPI AG - Multidisciplinary Digital Publishing Institute"]
[null,null,"Pubbl/distr/stampa",null,"[Place of publication not identified] : , : MDPI AG - Multidisciplinary Digital Publishing Institute, , 2016"]
[null,null,"Descrizione fisica",null,"1 online resource (274 pages)"]
[null,null,"Disciplina",null,"599.935"]
[null,null,"Soggetti",null,"Human gene mapping"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,"Nota di contenuto",null,"List of Contributors -- VII -- Preface XI -- Debra J. H. Mathews and Leila Jamal, Revisiting Respect for Persons in Genomic Research -- Reprinted from: Genes 2014, 5(1), 1-12  http://www.mdpi.com/2073-4425/5/1/1 1 -- Vincent Timmerman, Alleene V. Strickland and Stephan Züchner -- Genetics of Charcot-Marie-Tooth (CMT) Disease within the Frame of the Human Genome Project Success -- Reprinted from: Genes 2014, 5(1), 13-32 http://www.mdpi.com/2073-4425/5/1/13 13 -- Megan E. Aldrup-MacDonald and Beth A. Sullivan -- The Past, Present, and Future of Human Centromere Genomics -- Reprinted from: Genes 2014, 5(1), 33-50 -- http://www.mdpi.com/2073-4425/5/1/33 32 -- Nathalie Chami and Guillaume Lettre -- Lessons and Implications from Genome-Wide Association Studies (GWAS) Findings of Blood Cell Phenotypes -- Reprinted from: Genes 2014, 5(1), 51-64 -- http://www.mdpi.com/2073-4425/5/1/51 49 -- Jose Russo, Julia Santucci-Pereira and Irma H. Russo -- The Genomic Signature of Breast Cancer Prevention -- Reprinted from: Genes 2014, 5(1), 65-83 -- http://www.mdpi.com/2073-4425/5/1/65 63 --  IV -- Katsushi Tokunaga -- Lessons from Genome-Wide Search for Disease-Related Genes with Special Reference to HLA-Disease Associations -- Reprinted from: Genes 2014, 5(1), 84-96 -- http://www.mdpi.com/2073-4425/5/1/84 82 -- Hannelore Ehrenreich and Klaus-Armin Nave Phenotype-Based Genetic Association Studies (PGAS)-Towards Understanding the Contribution of Common Genetic Variants to Schizophrenia Subphenotypes -- Reprinted from: Genes 2014, 5(1), 97-105 -- http://www.mdpi.com/2073-4425/5/1/97 95 --  Albino Bacolla, David N. Cooper and Karen M. Vasquez -- Mechanisms of Base "]
[{"$nulls":4},"Substitution Mutagenesis in Cancer Genomes --Reprinted from: Genes 2014, 5(1), 108-146 -- http://www.mdpi.com/2073-4425/5/1/108 104 -- Muhammad Imran Khan, Maleeha Azam, Muhammad Ajmal, Rob W. J. Collin, Anneke I. den Hollander, Frans P. M. Cremers and Raheel Qamar -- The Molecular Basis of Retinal Dystrophies in Pakistan -- Reprinted from: Genes 2014, 5(1), 176-195 -- http://www.mdpi.com/2073-4425/5/1/176 144 -- Sara L. Pulit, Maarten Leusink, Androniki Menelaou and Paul I. W. de Bakker -- Association Claims in the Sequencing Era -- Reprinted from: Genes 2014, 5(1), 196-213 -- http://www.mdpi.com/2073-4425/5/1/196 163 -- Megan J. Puckelwartz and Elizabeth M. McNally -- Genetic Profiling for Risk Reduction in Human Cardiovascular Disease -- Reprinted from: Genes 2014, 5(1), 214-234 -- http://www.mdpi.com/2073-4425/5/1/214 181 --  David J. Elliott -- Illuminating the Transcriptome through the Genome -- Reprinted from: Genes 2014, 5(1), 235-253 -- http://www.mdpi.com/2073-4425/5/1/235 203 -- V -- Nicola Whiffin and Richard S. Houlston -- Architecture of Inherited Susceptibility to Colorectal Cancer: A Voyage of Discovery -- Reprinted from: Genes 2014, 5(2), 270-284 -- http://www.mdpi.com/2073-4425/5/2/270 222 -- Dianne F. Newbury, Anthony P. Monaco and Silvia Paracchini -- Reading and Language Disorders: The Importance of Both Quantity and Quality -- Reprinted from: Genes 2014, 5(2), 285-309 -- http://www.mdpi.com/2073-4425/5/2/285 237."]
[null,null,null,"Sommario/riassunto","In 1990, scientists began working together on one of the largest biological research projects ever proposed. The project proposed to sequence the three billion nucleotides in the human genome. The Human Genome Project took 13 years and was completed in April 2003, at a cost of approximately three billion dollars. It was a major scientific achievement that forever changed the understanding of our own nature. The sequencing of the human genome was in many ways a triumph for technology as much as it was for science. From the Human Genome Project, powerful technologies have been developed (e.g., microarrays and next generation sequencing) and new branches of science have emerged (e.g., functional genomics and pharmacogenomics), paving new ways for advancing genomic research and medical applications of genomics in the 21st century. The investigations have provided new tests and drug targets, as well as insights into the basis of human development and diagnosis/treatment of cancer and several mysterious humans diseases. This genomic revolution is prompting a new era in medicine, which brings both challenges and opportunities. Parallel to the promising advances over the last decade, the study of the human genome has also revealed how complicated human biology is, and how much remains to be understood. The legacy of the understanding of our genome has just begun. To celebrate the 10th anniversary of the essential completion of the Human Genome Project, in April 2013 Genes launched this Special Issue, which highlights the recent scientific breakthroughs in human genomics, with a collection of papers written by authors who are leading experts in the field."]