{"text_format":"2","workbook":"xls","n_sheets":1,"sheets":["report2"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":1,"defined_names":1,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"report2","index":0,"n_rows":18,"n_cols":5,"rows_kept":18,"cut":false,"hidden":false,"merged":[[0,2,0,3],[0,4,0,5],[1,2,1,3],[1,4,1,5],[2,2,2,3],[4,2,4,3],[6,2,6,3],[7,2,7,3],[8,2,8,3],[10,2,10,3],[11,2,11,3],[14,2,14,3]],"flags":["formulas_cached_only"]}
[null,"1.","Record Nr.",null,"UNINA9910574055003321"]
[null,null,"Titolo",null,"Synovial fluid analysis and the evaluation of patients with arthritis / / edited by Brian F. Mandell"]
[null,null,"Pubbl/distr/stampa",null,"Cham, Switzerland : , : Springer, , [2022]"]
[{"$nulls":4},"©2022"]
[null,null,"ISBN",null,"9783030996123"]
[{"$nulls":4},"9783030996116"]
[null,null,"Descrizione fisica",null,"1 online resource (165 pages)"]
[null,null,"Disciplina",null,"616.722"]
[null,null,"Soggetti",null,"Rheumatology"]
[{"$nulls":4},"Synovial fluid - Examination"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Intro -- Contents -- Contributors -- Chapter 1: The Impact of Synovial Fluid Analysis on Clinical Practice - Introduction -- References -- Chapter 2: Synovial Structure and Physiology in Health and Disease -- Introduction -- Synovial Intima -- Type B Synoviocytes -- Type A Synoviocytes -- Synovial Subintima -- Lining vs. Sublining Macrophages -- Subintimal Stromal Cells -- Subintimal Vasculature -- Synovial Inflammation in Disease -- Synovial Tissue Pathology -- Mechanisms of Cell Homing in Synovitis -- Pathologic Changes to Synovial Vasculature and Lymphatics -- Summary and Conclusions -- References -- Chapter 3: Arthrocentesis -- Indications and Contraindications -- Informed Consent -- Mandatory Requirements: Skin Antiseptic, Sterile Equipment, Aseptic Practice -- Everything Else Is Optional: Anesthesia, Injectate, Technique -- Injectate -- Post-procedure Recommendations -- Failed Arthrocentesis and the Use of Image-Guided Procedures -- References -- Chapter 4: Biochemical Composition of Synovial Fluid in Health and Disease -- Lubricant Molecules -- Proteins -- Small Molecules -- References -- Chapter 5: Cellular Components of Synovial Fluid in Health and Disease -- Origin and Nature of Normal Synovial Fluid -- Synovial Fluid Cell Types -- Mechanisms of Synovial Cell Counting -- Synovial Fluid Lymphocytes and Arthritis -- Synovial Fluid Monocytes/Macrophages and Arthritis -- Synovial Fluid Polymorphonuclear Leukocytes and Arthritis -- Synovial Fluid Eosinophils and Arthritis -- Summary -- "]
[{"$nulls":4},"References -- Chapter 6: Microbiology and Culture Identification of Infections -- The Pathogens -- Specimen Collection -- Specimen Handling and Transport -- Stains -- Culture Media and Incubation -- Special Considerations for Diagnosis of Prosthetic Joint Infections -- References -- Chapter 7: Molecular Microbiology for Diagnosing Infectious Arthritis."]
[{"$nulls":4},"Introduction to Molecular Microbiology Testing of Synovial Fluid and Joint Specimens -- Benefits and Limitations of Available Techniques -- Broad-Range Assays and Next-Generation Sequencing -- Pathogen-Specific Assays -- Acceptable Specimen Types and Specimen Handling -- Specimen Types -- Specimen Handling -- Specimen Storage -- Specimen Selection to Maximize Clinical Yield -- Emerging Technology -- Conclusions -- References -- Chapter 8: Basics of Light Microscopic Analysis of Synovial Fluid -- Practical Aspects of Light Microscopy -- Sample Handling -- Gram Stain of Initial Synovial Fluid Sample -- Unusual Cells -- References -- Chapter 9: Basics of Polarized Light Microscopy -- Introduction -- Basic Principles -- The Polarized Light Microscope -- Practice -- Monosodium Urate Crystals -- Calcium Pyrophosphate Crystals -- Birefringent Artifacts -- Conclusion -- References -- Chapter 10: Crystal-Associated Arthritis: Gout -- Characteristic of SF Samples in Gout -- Microscopy Characteristics of MSU Crystals -- Ordinary Light Microscopy (OLM) -- Polarized Light Microscopy (PLM) -- Avoiding False-Negative Results -- Avoiding False-Positive Results -- MSU Crystals in SF Samples From Asymptomatic Joints -- \"Never Symptomatic\" Joints in Patients with Hyperuricemia -- Asymptomatic Joints Previously Affected by Gout Flares -- Coexistence of MSU Crystals in Patients with Other Causes of Arthritis -- Coexistent Gout and Infection -- Coexistent CPP and MSU Crystals -- Diagnosis of Gout in Tissue Sample -- Histopathology of Synovial Membrane -- Histopathology of Subcutaneous Tophi -- References -- Chapter 11: Crystal-Associated Arthritis: Calcium Pyrophosphate Arthritis -- CPP Crystal Detection and Identification -- Mimics of CPP Crystals -- Effects of Delays Prior to Observation, Transportation, and Processing Issues."]
[{"$nulls":4},"Quality Control Between Different Observers for CPP Identification -- CPP Crystals in Synovial Tissue and in Cartilage at Time of Joint Replacement -- References -- Chapter 12: Lipid Crystals -- Cholesterol Crystals -- Clinical Settings -- Punctates -- Microscopy -- Clinical Significance -- Liquid Lipid Crystals, i.e., Maltese Crosses -- Clinical Settings -- Punctates -- Microscopy -- Clinical Significance -- Other Crystalline Lipids and Lookalikes -- Discussion -- References -- Chapter 13: Analytic Methods to Detect Articular Basic Calcium Phosphate Crystals -- Introduction -- Challenges of BCP Crystal Identification -- Alizarin Red S Staining -- Other Chemical Methods for Identifying BCP Crystals in Synovial Fluid -- Imaging Methods -- Chemical Identification Methods -- Clinical Imaging Modalities -- Conclusions and Future Directions -- References -- Chapter 14: Novel Techniques for Synovial Fluid Crystal Analysis -- Introduction -- Enhanced Microscopic Imaging -- Single-Shot Computational Polarized Light Microscopy -- Optical Diffraction Tomography -- Lens-Free Polarized Microscope Wide-Field Imaging -- Other Enhanced Synovial Fluid Analysis -- Raman Spectroscopy -- Other Imaging Techniques -- Conclusion -- References -- Chapter 15: Atlas of Images - Normal and Abnormal Synovial Fluid -- Index."]