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[null,"1.","Record Nr.",null,"UNINA9910566476003321"]
[null,null,"Autore",null,"Kreider Richard B"]
[null,null,"Titolo",null,"Creatine Supplementation for Health and Clinical Diseases"]
[null,null,"Pubbl/distr/stampa",null,"Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022"]
[null,null,"Descrizione fisica",null,"1 online resource (562 p.)"]
[null,null,"Soggetti",null,"Biology, life sciences"]
[{"$nulls":4},"Food & society"]
[{"$nulls":4},"Research & information: general"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Sommario/riassunto","Creatine plays a critical role in cellular metabolism, primarily by binding with phosphate to form phosphocreatine (PCr) as well as shuttling high-energy phosphate compounds in and out of the mitochondria for metabolism. Increasing the dietary availability of creatine increases the tissue and cellular availability of PCr, and thereby enhances the ability to maintain high-energy states during intense exercise. For this reason, creatine monohydrate has been extensively studied as an ergogenic aid for exercise, training, and sport. Limitations in the ability to synthesize creatine and transport and/or store dietary creatine can impair metabolism and is a contributor to several disease states.  Additionally, creatine provides an important source of energy during metabolically stressed states, particularly when oxygen availability is limited. Thus, researchers have assessed the role of creatine supplementation on health throughout the lifespan, as well as whether creatine availability may improve disease management and/or therapeutic outcomes. This book provides a comprehensive overview of scientific and medical evidence related to creatine's role in metabolism, health throughout the lifespan, and our current understanding of how creatine can promote brain, heart, vascular and immune health; reduce the severity of musculoskeletal and brain injury; and may provide therapeutic benefits in glucose management and diabetes, cancer therapy, inflammatory bowel disease, and post-viral fatigue."]
[null,"2.","Record Nr.",null,"UNINA9910619472103321"]
[null,null,"Autore",null,"Neduzha Larysa"]
[null,null,"Titolo",null,"Running Dynamics of Rail Vehicles"]
[null,null,"Pubbl/distr/stampa",null,"MDPI - Multidisciplinary Digital Publishing Institute, 2022"]
[null,null,"ISBN",null,"3-0365-5380-0"]
[null,null,"Descrizione fisica",null,"1 online resource (152 p.)"]
[null,null,"Soggetti",null,"Environmental science, engineering and technology"]
[{"$nulls":4},"History of engineering and technology"]
[{"$nulls":4},"Technology: general issues"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Sommario/riassunto","The investigation of rail vehicle running dynamics plays an important role in the more than 200 year development of railway vehicles and infrastructure. Currently, there are a number of new requirements for rail transport associated with the reduced environmental impact, energy consumption and wear, whilst increasing train speed and passenger comfort. Therefore, the running dynamics of rail vehicles is still a research topic that requires improved simulation tools and experimental procedures. The book focuses on the current research topics in railway vehicles running dynamics. Special attention is given to high-speed railway transport, acoustic and vibrational impact of railway transport to the surroundings, optimization of energy supply systems for railway transport, traction drives optimization and wear of wheels and rails."]