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[null,"1.","Record Nr.",null,"UNISALENTO991001405379707536"]
[null,null,"Autore",null,"Shimpuku, Taro"]
[null,null,"Titolo",null,"Symmetric algebras : by direct product of Clifford algebra / Taro Shimpuku"]
[null,null,"Pubbl/distr/stampa",null,"Osaka : Seibunsha publ., 1988"]
[null,null,"ISBN",null,"4792060184"]
[null,null,"Descrizione fisica",null,"xi, 491 p. ; 27 cm."]
[null,null,"Classificazione",null,"AMS 15-XX"]
[{"$nulls":4},"AMS 15A66"]
[null,null,"Disciplina",null,"512.57"]
[null,null,"Soggetti",null,"Clifford algebras"]
[{"$nulls":4},"Spinors analysis"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,"2.","Record Nr.",null,"UNINA9910557304003321"]
[null,null,"Autore",null,"Denora Nunzio"]
[null,null,"Titolo",null,"Paediatric Formulation: Design and Development"]
[null,null,"Pubbl/distr/stampa",null,"Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021"]
[null,null,"Descrizione fisica",null,"1 online resource (205 p.)"]
[null,null,"Soggetti",null,"Medicine"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Sommario/riassunto","The development of paediatric medicines can be challenging since this is a different patient population with specific needs. A medicine designed for use in paediatric patients must consider the following aspects: patient population variability; the need for dose flexibility; route of administration; patient compliance; excipient tolerability. For example, the toxicity of excipients may differ in children compared to adults and children have different taste preferences. Globally, about 75% of drugs do not carry regulatory approval for use in children; worldwide, many medications prescribed for the treatment of paediatric diseases are used off-label, and less than 20% of package inserts have sufficient information for treating children. This book provides an update on both state-of-the-art methodology and operational challenges in paediatric formulation design and development. It aims at re-evaluating what is needed for more progress in the design and development of age-appropriate treatments for paediatric diseases, focusing on: formulation development; drug delivery design; efficacy, safety, and tolerability of drugs and excipients."]