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[null,"1.","Record Nr.",null,"UNINA9910416473203321"]
[null,null,"Autore",null,"Drulhe Marcel"]
[null,null,"Titolo",null,"La santé à cœur ouvert : Sociologie du bien-être, de la maladie et du soin / / Marcel Drulhe, François Sicot"]
[null,null,"Pubbl/distr/stampa",null,"Toulouse, : Presses universitaires du Midi, 2019"]
[null,null,"ISBN",null,"2-8107-1036-8"]
[null,null,"Descrizione fisica",null,"1 online resource (305 p.)"]
[null,null,"Soggetti",null,"Public Health &amp; Health Care Science"]
[{"$nulls":4},"Sociology"]
[{"$nulls":4},"santé"]
[{"$nulls":4},"bien-être"]
[{"$nulls":4},"maladie"]
[{"$nulls":4},"soin"]
[null,null,"Lingua di pubblicazione",null,"Francese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Sommario/riassunto","La santé est un enjeu majeur de notre vie quotidienne, tant dans la sphère privée que publique, et les scandales de ces dernières années (du sang contaminé au Médiator) témoignent de cette préoccupation grandissante. Recherche d’épanouissement personnel, exploitation optimale des capacités de chacun, sensibilité accrue aux risques, exigence de protection et de bien-être : tous ces éléments attisent le débat autour des dispositifs de prévention, d’entretien, de promotion ou de réparation.  La sociologie ne saurait rester à l’écart de ces questions. Le présent ouvrage se propose d’analyser en profondeur les inégalités face à la santé, le fonctionnement du système de soins et l’évolution actuelle des pratiques (tensions entre cure et care, brouillage des frontières entre normal et pathologique, etc.). Il aborde aussi des questions éminemment sensibles : nouvelles lois de bioéthique, prise en charge croissante de la mort par l’hôpital, vieillissement, problèmes liés au handicap et à la dépendance.  Véritable introduction à une sociologie de la santé et du « vivre ensemble », ce livre en prise directe avec la recherche la plus récente a pour ambition de devenir un outil de référence destiné aux étudiants et aux chercheurs en sociologie, mais aussi aux très nombreux acteurs intervenant dans le domaine de la santé."]
[null,"2.","Record Nr.",null,"UNINA9910557116703321"]
[null,null,"Autore",null,"Ishii Kenichiro"]
[null,null,"Titolo",null,"Cytobiology of Human Prostate Cancer Cells and Its Clinical Applications"]
[null,null,"Pubbl/distr/stampa",null,"Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020"]
[null,null,"Descrizione fisica",null,"1 online resource (184 p.)"]
[null,null,"Soggetti",null,"Medicine"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Sommario/riassunto","The number of males diagnosed with prostate cancer (PCa) is increasing all over the world. Most patients with early-stage PCa can be treated with appropriate therapy, such as radical prostatectomy or irradiation. On the other hand, androgen deprivation therapy (ADT) is the standard systemic therapy given to patients with advanced PCa. ADT induces temporary remission, but the majority of patients (approximately 60%) eventually progress to castration-resistant prostate cancer (CRPC), which is associated with a high mortality rate. Generally, well-differentiated PCa cells are androgen dependent, i.e., androgen receptor (AR) signalling regulates cell cycle and differentiation. The loss of AR signalling after ADT triggers androgen-independent outgrowth, generating poorly differentiated, uncontrollable PCa cells. Once PCa cells lose their sensitivity to ADT, effective therapies are limited. In the last few years, however, several new options for the treatment of CRPC have been approved, e.g., the CYP17 inhibitor, the AR antagonist, and the taxane. Despite this progress in the development of new drugs, there is a high medical need for optimizing the sequence and combination of approved drugs. Thus, the identification of predictive biomarkers may help in the context of personalized medicine to guide treatment decisions, improve clinical outcomes, and prevent unnecessary side effects. In this Special Issue Book, we focused on the cytobiology of human PCa cells and its clinical applications to develop a major step towards personalized medicine matched to the individual needs of patients with early-stage and advanced PCa and CRPC. We hope that this Special Issue Book attracts "]
[{"$nulls":4},"the attention of readers with expertise and interest in the cytobiology of PCa cells."]