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[null,"1.","Record Nr.",null,"UNINA9910510571003321"]
[null,null,"Autore",null,"Cascella Marco"]
[null,null,"Titolo",null,"Features and Management of Acute and Chronic Neuro-Covid"]
[null,null,"Pubbl/distr/stampa",null,"Cham : , : Springer International Publishing AG, , 2022"]
[{"$nulls":4},"©2022"]
[null,null,"ISBN",null,"9783030867058"]
[{"$nulls":4},"9783030867041"]
[null,null,"Descrizione fisica",null,"1 online resource (172 pages)"]
[null,null,"Soggetti",null,"Electronic books."]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,"Nota di contenuto",null,"Intro -- Foreword -- Preface -- Acknowledgments -- Contents -- Abbreviations -- 1: Pathophysiology of COVID-19-Associated Neurotoxicity -- 1.1  Introduction -- 1.2  Overview on Neurological Manifestations -- 1.3  Pathophysiology of COVID-19-Associated Neurotoxicity -- 1.3.1  The Issue of SARS-CoV-2 Neurotropism -- 1.3.1.1  The Evidence for SARS-CoV-2 in Nerve Tissue -- 1.3.1.2  Pathogenesis of Direct SARS-CoV-2 Damage -- 1.3.1.3  The Ligand-Receptor Interaction and \"Postreceptorial Mechanisms\" in Nervous Tissue -- 1.3.2  Mechanisms of Diffusion Towards the Nervous Tissue -- 1.3.2.1  The Hematogenous Route -- 1.3.2.2  The Neurogenic Pathway -- 1.3.2.3  Other Possible Routes -- 1.3.3  Immune-Mediated Neurological Processes -- 1.3.3.1  Cytokine Storm -- 1.3.3.2  Microglial Activation and Blood-Brain Barrier Damage -- 1.3.4  Gut-Brain Axis Involvement -- 1.3.5  Effects of Multiorgan Dysfunction -- 1.4  Potential Mechanisms for Long-Term Neurotoxicity -- 1.5  Pain and COVID-19: The COVID-Pain Issue -- 1.5.1  Acute Clinical Manifestations -- 1.5.2  Long-Term Painful Clinical Manifestations -- 1.6  Ongoing Clinical Research -- 1.7  Research Perspectives -- 1.8  Conclusions -- References -- 2: Acute Manifestations of Neuro-COVID -- 2.1  Introduction. Overview on Clinical Manifestations of the Disease -- 2.2  Pathogenic Mechanisms -- 2.3  Classification Approaches -- 2.4  Central Nervous System Manifestations -- 2.4.1  Headache and Dizziness -- 2.4.2  Acute Encephalopathy -- 2.4.3  Posterior Reversible Encephalopathy Syndrome -- 2.4.4  Seizures -- 2.4.5  Acute Cerebrovascular Diseases -- 2.4.6  Meningitis and Encephalitis -- 2.4.7  "]
[{"$nulls":4},"Acute Myelitis -- 2.5  PNS Manifestations -- 2.5.1  Hypo/Anosmia and Dysgeusia/Ageusia -- 2.5.2  Guillain-Barré Syndrome and Variants -- 2.5.3  Pain -- 2.6  Skeletal Muscle Manifestations -- 2.6.1  Asthenia and Myalgia."]
[{"$nulls":4},"2.6.2  Skeletal Muscle Injury -- 2.7  Psychiatric Manifestations -- 2.8  Conclusions -- References -- 3: Diagnostic Approaches to Acute Neuro-COVID -- 3.1  Introduction -- 3.2  Neuroimaging -- 3.2.1  Stroke -- 3.2.2  Cerebral Hemorrhagic Lesions -- 3.2.3  Mixed Pictures -- 3.2.4  Posterior Reversible Encephalopathy Syndrome -- 3.2.5  Encephalitis -- 3.2.6  Myelitis -- 3.2.7  Peripheral Nervous System and Muscular Disorders -- 3.2.8  Clinical and Neuroimaging Correlation -- 3.2.9  The Role of Brain Positron Emission Tomography -- 3.2.10  Other Diagnostic Approaches -- 3.3  Electrodiagnostic Tests -- 3.3.1  EEG: Indications, Approaches, Features, and Limitations -- 3.3.2  ICU-Acquired Weakness in COVID-19 Patients -- 3.3.3  Mixed CNS/PNS Pictures -- 3.4  Laboratory Tests -- 3.5  Neuropathological Findings -- 3.6  Conclusions -- References -- 4: Neurological, Psychological, and Cognitive Manifestations of Long-COVID -- 4.1  Introduction -- 4.2  The Long-COVID Phenomenon in Numbers -- 4.3  Neurological Symptoms -- 4.3.1  Mechanisms -- 4.3.2  Clinical Features -- 4.4  Psychological Sequelae of Long-COVID -- 4.4.1  Disease-Related or Pandemic-Induced Effects? -- 4.4.2  From Acute to Chronic Psychiatric Problems -- 4.5  Potential Long-Term Cognitive Issues -- 4.6  Conclusions -- References."]