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[null,null,"Titolo",null,"Clinical foundations of musculoskeletal medicine : a manual for medical students / / edited by Robert J. Esther"]
[null,null,"Pubbl/distr/stampa",null,"Cham, Switzerland : , : Springer, , [2021]"]
[null,null,"ISBN",null,"3-030-42894-X"]
[null,null,"Descrizione fisica",null,"1 online resource (412 pages)"]
[null,null,"Disciplina",null,"616.7"]
[null,null,"Soggetti",null,"Musculoskeletal system - Diseases"]
[{"$nulls":4},"Musculoskeletal system - Diseases - Diagnosis"]
[{"$nulls":4},"Aparell locomotor"]
[{"$nulls":4},"Medicina clínica"]
[{"$nulls":4},"Llibres electrònics"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Includes index."]
[null,null,"Nota di contenuto",null,"Intro -- Preface -- Contents -- Contributors -- Part I: Principles of Musculoskeletal Health and Disease -- 1: Incidence and Prevalence of Musculoskeletal Disease -- 1.1  Epidemiology of Musculoskeletal Conditions -- 1.2  Socioeconomic Impact of Musculoskeletal Disease -- 1.3  Developing Quality Education in Musculoskeletal Medicine -- References -- 2: Musculoskeletal Tissues and Anatomy -- 2.1  Joints -- 2.2  Cartilage -- 2.3  Bone -- 2.4  Bone Formation -- 2.5  Muscular System -- 2.6  Skeletal Muscle -- References -- 3: Introduction to Musculoskeletal Imaging -- 3.1  Conventional Radiography -- 3.2  Computed Tomography (CT) -- 3.3  Nuclear Medicine -- 3.4  Magnetic Resonance Imaging (MRI) -- 3.5  Ultrasound (US) -- 3.6  Interventional Radiology -- 3.7  Summary -- 4: Basic Bone Metabolism -- 4.1  Introduction -- 4.2  Important Definitions -- 4.3  Overview of the Skeletal System -- 4.3.1  Purposes -- 4.3.2  Structure -- 4.3.3  Bone Remodeling -- 4.4  Regulation of Bone Development -- 4.4.1  Hormones That Affect Calcium and Phosphate Homeostasis -- 4.4.2  Hormones That Affect Bone Resorption -- 4.5  Measures of Bone Quality and Turnover -- 4.5.1  Imaging -- 4.5.2  Biochemical Markers for Bone Turnover -- References -- 5: Principles of Diagnosis and Treatment of Bone Remodeling Disorders -- 5.1  Diagnosis of Bone Remodeling Disorders -- 5.1.1  Common Disorders of Bone Remodeling -- 5.1.1.1  Osteoporosis -- 5.1.1.2  Chronic Kidney "]
[{"$nulls":4},"Disease-Mineral and Bone Disorder -- 5.1.1.3  Paget's Disease of the Bone -- 5.1.1.4  Osteopetrosis -- 5.1.2  History -- 5.1.3  Physical Exam -- 5.1.4  Diagnostic Workup -- 5.1.4.1  Laboratory Abnormalities -- 5.1.4.2  Radiographic Changes -- 5.1.4.3  Role of Bone Biopsy -- 5.2  Treatment of Bone Remodeling Disorders -- 5.3  Diagnosis of Paget's Disease of the Bone -- 5.3.1  History and Clinical Presentation."]
[{"$nulls":4},"5.3.2  Physical Exam -- 5.3.3  Differential Diagnosis -- 5.3.4  Diagnostic Workup -- 5.3.4.1  Laboratory Abnormalities -- 5.3.4.2  Radiographic Changes -- 5.3.4.3  Bone Biopsy -- 5.4  Pathogenesis of Paget's Disease of the Bone -- 5.5  Treatment of Paget's Disease of the Bone -- 5.5.1  Indications for Treatment -- 5.5.2  Treatment Options -- 5.5.3  Side Effects -- 5.5.4  Monitoring -- 5.5.5  Retreatment -- 5.5.6  Surgery -- Referecnes -- 6: Principles of Diagnosis and Treatment of Osteomalacia -- 6.1  Definition of Osteomalacia -- 6.1.1  Clinical Presentation -- 6.1.2  Pathogenesis -- 6.1.3  Differential Diagnosis -- 6.1.4  Common Etiologies of Osteomalacia -- 6.1.5  Physical Exam Findings -- 6.1.6  Diagnostic Workup -- 6.1.6.1  Laboratory Abnormalities -- 6.1.6.2  Radiologic Changes -- 6.1.6.3  Bone Mineral Density Changes -- 6.1.6.4  Bone Biopsy -- 6.2  Etiology of Osteomalacia -- 6.2.1  Vitamin D Deficiency -- 6.2.2  Renal Disease -- 6.2.3  Medications -- 6.2.4  Hypophosphatemia -- 6.2.5  Hypophosphatasia -- 6.2.6  Tumor-Induced Osteomalacia -- 6.2.7  Rare Causes -- 6.3  Treatment -- References -- 7: Principles of Diagnosis and Treatment of Osteoporosis -- 7.1  Introduction -- 7.2  Important Definitions -- 7.3  Pathophysiology of Osteoporosis -- 7.3.1  Sex Hormone Deficiencies -- 7.3.2  Glucocorticoids and Other Medications -- 7.3.3  Other Factors -- 7.4  Diagnosis of Osteoporosis -- 7.4.1  History -- 7.4.2  Physical Exam -- 7.4.3  Diagnostic Workup -- 7.4.3.1  Laboratory -- 7.4.3.2  Imaging -- 7.4.3.3  Bone Biopsy -- 7.5  Treatment of Osteoporosis -- 7.5.1  Lifestyle Modifications -- 7.5.2  Calcium and Vitamin D -- 7.5.3  Bisphosphonates -- 7.5.3.1  Alendronate -- 7.5.3.2  Risedronate -- 7.5.3.3  Zoledronic Acid -- 7.5.3.4  Ibandronate -- 7.5.3.5  Serious Bisphosphonate Adverse Reactions -- 7.5.3.6  Atypical Femur Fractures."]
[{"$nulls":4},"7.5.3.7  Jaw Osteonecrosis -- 7.5.4  Denosumab -- 7.5.5  Teriparatide and Abaloparatide -- 7.5.6  Selective Estrogen Receptor Modulators -- 7.5.7  Estrogen Therapy -- 7.5.8  Special Populations -- 7.5.8.1  Premenopausal Women -- 7.5.8.2  Patients with Chronic Kidney Disease -- 7.5.8.3  Patients on Chronic Glucocorticoid Therapy -- References -- Part II: Rheumatic Diseases -- 8: Rheumatoid Arthritis -- 8.1  Risk Factors -- 8.2  Pathophysiology -- 8.3  Clinical Presentation -- 8.3.1  Articular Features -- 8.3.2  Extra-Articular Features -- 8.4  Laboratory Studies -- 8.5  Imaging -- 8.5.1  Plain Radiographs -- 8.5.2  Ultrasound -- 8.5.3  MRI -- 8.6  Diagnostic Approach -- 8.7  Treatment -- 8.7.1  Non-pharmacologic Management -- 8.7.2  Pharmacologic Therapy -- 8.7.3  Surgical Management -- References -- 9: Osteoarthritis -- 9.1  Epidemiology of Osteoarthritis -- 9.1.1  Classification Criteria -- 9.1.2  Definitions of Osteoarthritis -- 9.1.3  Frequency of Osteoarthritis -- 9.1.3.1  Radiographic Osteoarthritis -- 9.1.3.2  Symptomatic Osteoarthritis -- 9.1.3.3  Lifetime Risk of OA -- 9.2  Risk Factors and Etiology -- 9.3  Pathophysiology -- 9.4  Clinical Features -- 9.4.1  General -- 9.4.2  Joint-Specific -- 9.4.2.1  Knee -- 9.4.2.2  Hip -- 9.4.2.3  Hand -- 9.4.2.4  Other Sites -- 9.4.2.5  Multi-Joint -- 9.5  Diagnostic Testing -- 9.5.1  Laboratory Testing -- 9.5.2  Imaging Findings -- 9.5.2.1  Conventional Radiography -- 9.5.2.2  Magnetic Resonance Imaging -- 9.5.2.3  Ultrasound -- 9.6  Principles "]
[{"$nulls":4},"of Management -- 9.6.1  Non-pharmacologic -- 9.6.1.1  Education and Self-Management -- 9.6.1.2  Exercise and Weight Loss -- 9.6.1.3  Assistive Devices -- 9.6.1.4  Alternative and Complementary Approaches -- 9.6.1.5  Surgical Interventions -- 9.6.2  Pharmacologic -- 9.6.2.1  Intra-articular Therapy -- 9.7  Consequences and Comorbidities -- 9.8  Conclusion."]
[{"$nulls":4},"References -- 10: Seronegative Spondyloarthropathies -- 10.1  Introduction -- 10.2  Clinical Features -- 10.2.1  Musculoskeletal Features -- 10.2.2  Non-musculoskeletal Features -- 10.3  Physical Exam -- 10.4  Laboratory Features -- 10.5  Imaging -- 10.5.1  Plain Radiographs -- 10.5.2  Magnetic Resonance Imaging -- 10.6  Specific Forms of the Seronegative Spondyloarthropathies -- 10.6.1  Ankylosing Spondylitis -- 10.6.2  Non-radiographic Axial Spondyloarthropathy -- 10.6.3  Psoriatic Arthritis -- 10.6.4  IBD-Associated Arthritis -- 10.6.5  Reactive Arthritis -- 10.6.6  Juvenile Spondyloarthropathy -- 10.7  Treatment -- 10.7.1  Nonpharmacologic Strategies -- 10.7.2  Pharmacologic Strategies -- References -- 11: Systemic Lupus Erythematosus -- 11.1  Demographics and Epidemiology -- 11.2  Pathogenesis and Pathophysiology -- 11.3  Clinical Manifestations and Disease Course -- 11.3.1  Constitutional Symptoms -- 11.3.2  Skin and Mucous Membrane Involvement -- 11.3.3  Musculoskeletal -- 11.3.4  Cardiovascular -- 11.3.5  Lungs -- 11.3.6  Nervous System -- 11.3.7  Hematologic -- 11.3.8  Renal Disease -- 11.4  Autoimmune Serologies -- 11.5  Diagnosis -- 11.6  Treatment -- 11.6.1  Lifestyle Modifications -- 11.6.2  Pharmacologic Therapy -- 11.6.2.1  Hydroxychloroquine -- 11.6.2.2  Corticosteroids -- 11.6.2.3  Immunosuppressants -- 11.6.2.4  Biologic Therapy -- References -- 12: Crystalline Arthropathy -- 12.1  Gout -- 12.1.1  Epidemiology -- 12.1.2  Pathophysiology -- 12.1.3  Clinical Presentation -- 12.1.4  Diagnosis -- 12.1.5  Treatment -- 12.1.5.1  Lifestyle Modifications -- 12.1.5.2  Pharmacologic Therapy -- 12.2  Calcium Pyrophosphate Dihydrate Deposition (CPPD) Arthropathy or Pseudogout -- 12.2.1  Epidemiology -- 12.2.2  Pathophysiology -- 12.2.3  Clinical Presentation -- 12.2.4  Diagnosis -- 12.2.5  Treatment -- References."]
[{"$nulls":4},"Part III: Musculoskeletal Infection, Vascular, and Neoplastic Diseases -- 13: Microbes in Bone and Joint Infections -- 13.1  Osteomyelitis -- 13.1.1  Introduction -- 13.1.2  Acute Osteomyelitis -- 13.1.2.1  Acute Osteomyelitis in Sickle Cell Patients -- 13.1.3  Vertebral Osteomyelitis -- 13.1.3.1  Tuberculous Osteomyelitis -- 13.1.4  Diabetic Foot Osteomyelitis -- 13.2  Infective Arthritis -- 13.2.1  Introduction -- 13.2.2  Native Joint Arthritis -- 13.2.2.1  Bacterial (Septic) Arthritis -- Lyme Arthritis -- 13.2.2.2  Viral Arthritis -- 13.2.3  Prosthetic Joint Infections -- References -- 14: Principles of Musculoskeletal Infections -- 14.1  Osteomyelitis -- 14.1.1  Overview -- 14.1.1.1  Definition -- 14.1.1.2  Immune Response -- 14.1.1.3  Bone Response -- 14.1.1.4  Routes of Infection -- 14.1.2  Hematogenous Osteomyelitis -- 14.1.2.1  Pathogenesis -- 14.1.2.2  Bacteriology -- 14.1.2.3  Pathology -- 14.1.2.4  Radiographic Manifestations -- 14.1.2.5  Clinical Course -- 14.1.2.6  Complications -- 14.1.2.7  Treatment -- 14.1.3  Exogenous Osteomyelitis -- 14.1.3.1  Etiology -- 14.1.3.2  Pathology -- 14.1.3.3  Clinical Course -- 14.1.3.4  Fracture and Implant/Hardware Infection -- 14.2  Septic Arthritis -- 14.2.1  Etiology -- 14.2.2  Bacteriology -- 14.2.3  Pathogenesis -- 14.2.4  Clinical Features -- 14.2.5  Diagnosis -- 14.2.6  Treatment -- 14.2.7  Complications -- 14.3  Prosthetic Joint Infection -- 14.3.1  Etiology -- 14.3.2  Bacteriology -- 14.3.3  Clinical Features -- 14.3.4  Diagnosis -- 14.3.5  Treatment -- 14.3.6  Complications -- References -- 15: Vascular Disorders of Bone -- 15.1  Understanding Avascular Necrosis -- 15.2  Pathophysiology "]
[{"$nulls":4},"of Avascular Necrosis -- 15.3  Avascular Necrosis Throughout the Musculoskeletal System -- 15.4  Imaging Findings in Avascular Necrosis -- 15.5  Bone Infarct -- 15.6  Pediatric Osteochondroses."]
[{"$nulls":4},"15.6.1  Pathophysiology and Natural History."]