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[null,"1.","Record Nr.",null,"UNINA9910488720503321"]
[null,null,"Titolo",null,"Emerging technologies for nanoparticle manufacturing / / Jayvadan K. Patel, Yashwant V. Pathak, editors"]
[null,null,"Pubbl/distr/stampa",null,"Cham, Switzerland : , : Springer, , [2021]"]
[{"$nulls":4},"©2021"]
[null,null,"ISBN",null,"3-030-50703-3"]
[null,null,"Descrizione fisica",null,"1 online resource (604 pages)"]
[null,null,"Disciplina",null,"620.5"]
[null,null,"Soggetti",null,"Nanomanufacturing"]
[{"$nulls":4},"Nanopartícules"]
[{"$nulls":4},"Llibres electrònics"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Includes index."]
[null,null,"Nota di contenuto",null,"Intro -- Foreword -- Preface -- Acknowledgments -- Contents -- Part I: Introduction and Biomedical Applications of Nanoparticles -- 1: Introduction to Nanomaterials and Nanotechnology -- 1  Introduction -- 2  Nanomaterials -- 3  Why Are Nanoscale Materials: So Special and Unique? -- 4  Classification of Nanoscale Materials -- 4.1  Classification of Nanomaterials Based on Their Origin -- 4.2  Classification of Nanomaterials Based on the Chemical Composition -- 4.3  Material-Based Classification -- 4.4  Classification of Nanomaterials Based on Their Dimensions -- 5  Properties: The Physics at the Nanoscale -- 5.1  Confinement Effect -- 5.2  Surface Effects -- 5.3  Mechanical Properties -- 5.4  Structural Properties -- 5.5  Thermal Properties -- 5.6  Optical Properties -- 5.7  Magnetic Properties -- 6  Nanomaterials Synthesis Strategies -- 6.1  Bottom-Up Procedures -- 6.2  Top-Down Procedures -- 7  Conclusion -- References -- 2: Biomedical Applications of Nanoparticles -- 1  Introduction -- 1.1  Applications of Nanoparticles in Biomedical -- 2  Conclusion -- References -- Part II: Polymeric Nanoparticles -- 3: Nanocrystallization and Nanoprecipitation Technologies -- 1  Introduction -- 2  Definition -- 3  Prominent Attributes -- 3.1  Surface Area Enlargement -- 3.2  Increase in Saturation Solubility -- 3.3  Crystalline or Amorphous Particle States -- 4  Production Technologies -- 5  Nanocrystallization and Nanoprecipitation Technologies -- 6  Media Milling -- 6.1  Mechanism Involved -- 6.2  Selection of Bead Size "]
[{"$nulls":4},"-- 6.3  Particle Surface Modification -- 7  Cryo-Milling -- 7.1  Definition -- 7.2  Ultra Cryo-Milling -- 8  Solvent-Antisolvent Precipitation -- 8.1  Fundamental Principle of Antisolvent Precipitation Techniques -- 8.2  Step-Up Antisolvent Precipitation Process -- 8.2.1  Mixing -- 8.2.2  Mixing Devices."]
[{"$nulls":4},"9  Role of Stabilizer in Antisolvent Precipitation Techniques -- 10  Future Perspectives -- References -- 4: Microfluidics Technology for Nanoparticles and Equipment -- 1  Introduction -- 2  Principle Foundation -- 3  Mixing -- 3.1  Active Micromixers -- 3.2  Passive Micromixers -- 4  Microfluidic Reactors: Features for the Manufacture of Nanoparticles -- 5  Design of the Reactor -- 6  Fabrication of Microfluidic Devices -- 7  Microfluidic Devices: Types -- 8  Formulation of Nano Drug Delivery System Using Microfluidics -- 8.1  Pure Drug Nanoparticles -- 8.1.1  Crystalline Drug Nanoparticles -- 8.2  Amorphous Drug Nanoparticles -- 8.3  API Loaded Nanoparticles Generated Using Microfluidic Technology -- 9  Microfluidic and Bulk Technologies: Comparison (Jahn et al. 2007) -- 10  Microfluidics: Nanoparticles Drug Delivery -- 10.1  Flow Focusing Method -- 10.2  Micro-vortices Method -- 10.3  Chaotic Flow Method -- 10.4  Droplets Method -- 10.5  Other Methods -- 11  Microfluidics: Nanoparticles Characterization -- 11.1  Characterization of Particle Size and Morphology -- 11.2  Charge Characterization -- 11.3  Characterization of Drug Loading and Drug Release -- 12  Microfluidics: Nanoparticle Evaluation -- 13  Production of Nanoparticles Using Microfluidic Devices -- 13.1  Lipid Nanoparticles (LNPs) -- 13.2  Polymeric Nanoparticles -- 13.3  Theranostic Nanoparticles -- 14  Microfluidic Tools for Nanoparticles Investigation -- 14.1  Organ-on-a-Chip -- 14.2  Blood Vessel-on-a-Chip -- 14.3  Blood Brain Barrier-on-a-Chip -- 14.4  Tumour-on-a-Chip -- 14.5  Lung-on-a-Chip -- 14.6  Liver-on-a-Chip -- 14.7  Kidney-on-a-Chip -- 14.8  Heart-on-a-Chip -- 15  Companies Working on Microfluidic Technology -- 16  Future Developments -- 17  Conclusion -- References -- 5: Production of Nanocomposites via Extrusion Techniques -- 1  Introduction."]
[{"$nulls":4},"2  Polymeric Nanocomposites by Extrusion Method -- 3  Metal Matrix Nanocomposites Prepared by Extrusion Method -- 4  Conclusion -- References -- 6: The Use of Supercritical Fluid Technologies for Nanoparticle Production -- 1  Introduction -- 2  Supercritical Fluid Technology -- 3  Supercritical Fluids -- 4  Supercritical Processes for Nanoparticles Manufacturing -- 4.1  Particles from Gas-Saturated Solutions (PGSS) -- 4.2  Rapid Expansion of Supercritical Solutions (RESS) -- 4.3  Gas Anti-solvent Processes (GAS) -- 4.4  Supercritical Anti-solvent Processes (SAS) -- 4.5  Aerosol Solvent Extraction System (ASES) -- 4.6  Supercritical Anti-solvent with Enhanced Mass Transfer (SAS-EM) -- 4.7  Solution-Enhanced Dispersion by Supercritical Fluids (SEDS) -- 4.8  Suspension-Enhanced Dispersion by Supercritical Fluids (SpEDS Process) -- 4.9  Supercritical Assisted Atomization (SAA) -- 5  Application of SCF for Production of Nanoparticles -- 6  Summary and Future Perspective -- References -- 7: Salting Out and Ionic Gelation Manufacturing Techniques for Nanoparticles -- 1  Introduction -- 2  Nanotechnology in Drug Delivery Systems -- 3  Polymeric Nanoparticles -- 4  Drug Releasing Mechanism of Nanoparticles -- 5  Development of Polymeric Nanoparticles -- 5.1  Polymerization -- 5.1.1  Emulsion-Polymerization Technique -- 5.1.2  Interfacial Polymerization Technique -- 5.2  Development of Polymeric Nanoparticles From Preformed Polymers -- 5.2.1  Emulsification and Solvent Evaporation Method -- 5.2.2  Solvent Displacement Technique -- 5.2.3  Interfacial Deposition Technique -- 5.2.4  "]
[{"$nulls":4},"Emulsification and Solvent Diffusion -- 5.2.5  Salting-Out Method -- Effect of Various Parameters on Salting-Out Technique -- Advantages of the Salting-Out Method -- Disadvantages of the Salting-Out Method -- Scale-Up of the Salting-Out Method."]
[{"$nulls":4},"Effect of Process Parameters on the Quality of the Nanoformulation During the Scale-Up of Method -- The Theoretical Model for the Preparation of Nanoparticles by the Salting-Out Method -- Relation of the Rate of Stirring to the Nanoparticle Size -- Model for Drug Transport From the Salted-Out Scaffold -- Salting-Out Method and Transition of Polymer Properties -- Applications of the Salting-Out Method -- Preparation of PLGA- and PLA-Based Nanoformulations -- Preparation of Polymeric Nanoparticles for Gene Therapy by the Salting-Out Method -- Interactions Between Crosslinking Ions and Polymeric Chains -- Combination of the Salting-Out Method with Other Methods -- Emulsion Solvent Evaporation-Salting-Out Technique -- Emulsion-Based and Aqueous-Based Salting-Out Method -- 5.2.6  Supercritical Fluid Technology -- 5.2.7  Rapid Expansion of Supercritical Solution (RESS) -- 5.2.8  Rapid Expansion of Supercritical Solution into a Liquid Solvent -- 5.2.9  Electrospraying Technology -- 5.2.10  Ionic Gelation Method -- Chitosan-Based Nanoformulations -- Characterization of Chitosan -- Molecular Weight Determination -- Calculation of the Degree of Deacetylation -- Chitosan-Based Nanoparticles and Ionic Gelation Method -- 5.2.11  Microreactor Application in the Preparation of Chitosan Nanoparticles by Ionic Gelation Method -- 5.2.12  Theoretical Analysis of Nanoparticle Preparation by Ionic Gelation Method in a Microreactor -- 5.2.13  Hydrogels of Drug-Loaded Chitosan-Based Nanoparticle -- 5.2.14  Preparation of Alginate-Based Nanoparticles by Ionic Gelation Method -- Alginate Hydrogels -- Factors Influencing the Crosslinking Degree of Alginate-Based Hydrogels -- Evaluation of Hydrogels -- Preparation of Sodium Alginate Nanoparticles by Ionic Gelation Method -- Preparation Sodium Pectin-Based Nanoparticles by Ionic Gelation Method."]
[{"$nulls":4},"Ionic Gelation Method for the Preparation of Nanogels -- Ionic Gelation Method for the Development of Nanoparticles Loaded Films -- 5.3  Effect of Process Parameters on the Quality of Nanoformulations -- 5.3.1  Polymer -- 5.3.2  Crosslinking Agent -- 5.3.3  Polymer and Drug Ratio -- 5.3.4  Sonication -- 5.4  Effect of Morphological and Physicochemical Properties on the Quality of Nanoformulation -- 5.4.1  Particle Size -- 5.4.2  Drug Loading and Entrapment Efficiency -- 5.4.3  Drug Release Kinetics -- 5.4.4  Degree of Swelling -- 5.4.5  Zeta Potential -- 5.4.6  Cellular Uptake of Nanoparticles -- 5.5  Modified Traditional Methods for the Development of Nanoparticles -- 5.5.1  Dialysis -- 5.5.2  Membrane Evaporation and Emulsion Technique -- 5.5.3  Premix Membrane Emulsification -- 5.5.4  Spray-Dry Method -- 5.5.5  Spray Solvent Displacement Combined with Dialysis -- 6  Conclusion -- References -- 8: Nanogel Synthesis by Irradiation of Aqueous Polymer Solutions -- 1  Introduction -- 2  Nanosized Particles in Medicine -- 3  Nanogels: Highlights and Applications -- 4  Synthesis Methods of Nanogels -- 4.1  Crosslinking/Polymerization of Monomer or Monomer Mixtures -- 4.2  Crosslinking of Preformed Polymers -- 5  Radiation-Induced Synthesis of Nanogels -- 5.1  Radiation Chemistry of Aqueous Systems -- 6  Conclusions and Future Prospects -- References -- 9: Cellulose Acetate-Based Nanofibers: Synthesis, Manufacturing, and Applications -- 1  Introduction -- 2  Derivatives of CA Polymer -- 3  Synthesis and Manufacturing of CA-Based Nanofibers -- 3.1  Electrospinning Process and Mechanism -- 3.2  Solvent Selection -- 3.2.1  Acetone-Based Solvent Systems -- (a) "]
[{"$nulls":4},"Using Water Acetone System -- (b) Acetone-DMF System -- (c) Using Acetone-DMAc Solvents -- 3.2.2  Other Solvent Systems -- 3.3  Deacetylation Study -- 4  Application of CA Nanofibers."]
[{"$nulls":4},"4.1  Antibacterial Application."]