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[null,"1.","Record Nr.",null,"UNINA9910465409103321"]
[null,null,"Titolo",null,"Multilingual individuals and multilingual societies [[electronic resource] /] / edited by Kurt Braunmüller, Christoph Gabriel"]
[null,null,"Pubbl/distr/stampa",null,"Amsterdam ; ; Philadelphia, : John Benjamins Pub. Co., 2012"]
[null,null,"ISBN",null,"1-283-54898-4"]
[{"$nulls":4},"9786613861436"]
[{"$nulls":4},"90-272-7349-9"]
[null,null,"Descrizione fisica",null,"1 online resource (490 p.)"]
[null,null,"Collana",null,"Hamburg studies on multilingualism (HSM) ; ; 13"]
[null,null,"Disciplina",null,"306.44/6"]
[null,null,"Soggetti",null,"Multilingualism - Social aspects"]
[{"$nulls":4},"Languages in contact"]
[{"$nulls":4},"Sociolinguistics"]
[{"$nulls":4},"Electronic books."]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Multilingual Individuals and Multilingual Societies; Editorial page; Title page; LCC data; Acknowledgement; Table of contents; Foreword; References; Part I. How language is acquired and lost in multilingual settings; Case marking in child L1 and early child L2 German; 1. Introduction; 2. The German case system; 2.1 Case forms in German; 2.2 Structural case vs. lexical case; 3. The acquisition of case in German; 3.1 An overview; 3.2 The study by Eisenbeiss et al. (2006): Case marking by monolingual German children; 3.3 The criteria used by Eisenbeiss et al. in their analysis of case"]
[{"$nulls":4},"4. Spontaneous production data from successive bilingual children with L1 Turkish 5. Experimental data from monolingual and successive bilingual children; 6. Discussion; 7. Conclusions; References; First exposure learners make use of top-down lexical knowledge when learning words; 1. Experience and L1 knowledge in L2 word learning; 2. Segmenting sound forms, recognizing words and making form-meaning correspondences; 3. Why study first exposure learners?; 4. Our studies; 4.1 Methodology and stimuli; 4.2 Participants; 4.3 Results; 5. Discussion and conclusions; References; Wh-questions in Dutch"]
[{"$nulls":4},"1. Introduction 2. Cross-linguistic influence in multilingual acquisition; 3. Wh-questions in Dutch, French and Italian; 3.1 Syntax of wh-questions in Dutch, French and Italian; 3.2 Monolingual acquisition of "]
[{"$nulls":4},"wh-questions in Dutch, French and Italian; 3.3 Multilingual acquisition of wh-questions; 4. Study; 4.1 Hypotheses; 4.2 Participants; 4.3 Experimental task; 4.4 Results; 5. Discussion and conclusions; References; The emergence of a new variety of Russian in a language contact situation; 1. Background; 1.1 The subject of the study; 1.2 Why negation?; 1.3 The functions of negation"]
[{"$nulls":4},"1.4 Negation in Russian 1.5 Negation in Swedish; 2. Negation in Julia's data; 2.1 Pre-verbal negation: Gestures; 2.2 Verbal negation; 3. Discussion; 4. Conclusion; References; The acquisition of gender agreement marking in Polish; 1. Introduction; 2. Gender classes, gender agreement and gender assignment in Polish; 3. State of the art; 3.1 The acquisition of gender in Polish; 3.2 The acquisition of gender in bilingual children; 4. Design of the present study; 4.1 Participants; 4.2 Methods; 5. Results; 5.1 Correlation of age and correctness"]
[{"$nulls":4},"5.2 Correctness of gender markings with typical, atypical and nonce nouns 5.3 Error analyses; 6. General discussion and conclusion; References; Discourse cohesion in the elicited narratives of early Russian-German sequential bilinguals; 1. Introduction; 1.1 Discourse cohesion and coherence in narratives; 1.2 Some facts about the acquisition of Russian; 2. Method; 3. Results and discussion; 4. Conclusion; Appendix; References; German segments in the speech of German-Spanish bilingual children; 1. Introduction; 2. The German voicing contrast; 2.1 Theoretical description and acquisition"]
[{"$nulls":4},"2.2 The study"]
[null,null,null,"Sommario/riassunto","The 25 contributions of this volume represent a selection from the more than 120 papers originally presented at the International Conference on \"Multilingual Individuals and Multilingual Societies\" (MIMS), held in Hamburg (October 2010) and organized by the Collaborative Research Center \"Multilingualism\" after twelve years of successful research. It presents a panorama of contemporary research in multilingualism covering three fields of investigation: (1) the simultaneous and successive acquisition of more than one language, including language attrition in multilingual settings, (2) historical"]
[null,"2.","Record Nr.",null,"UNINA9910784395003321"]
[null,null,"Autore",null,"Carlucci Frank Charles <1930-2018.>"]
[null,null,"Titolo",null,"Taking charge : a bipartisan report to the president-elect on foreign policy and national security / / Transition 2001, Frank Carlucci, Robert E. Hunter, Zalmay Khalilzad, co-chairs"]
[null,null,"Pubbl/distr/stampa",null,"Santa Monica, CA : , : RAND Corporation, , 2001"]
[null,null,"ISBN",null,"1-60129-002-0"]
[null,null,"Descrizione fisica",null,"1 online resource  (xvii, 74 pages)"]
[null,null,"Disciplina",null,"327.73"]
[{"$nulls":4},"355.0310973"]
[null,null,"Soggetti",null,"United States - Foreign relations - 1993-2001"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,"Nota di contenuto",null,"Preface; Transmittal Letter to the President-Elect; Chapter One:  Introduction:  Setting Directions for the Global Era; Chapter Two:  First Steps:  The Transition and After Inauguration; Chapter Three:  Setting the Stage:  Longer-Term Issues; Appendix:  Comments and Dissent by Transition 2001 Panel Members"]
[null,null,null,"Sommario/riassunto","A collection of discussion papers, prepared by RAND staff and others, that analyze the most critical foreign and national security issues facing the United States, both during the early days of the Bush administration and in the long term."]
[null,"3.","Record Nr.",null,"UNINA9910830389103321"]
[null,null,"Titolo",null,"Medicinal chemistry of bioactive natural products [[electronic resource] /] / edited by Xiao-Tian Liang,  Wei-Shuo Fang"]
[null,null,"Pubbl/distr/stampa",null,"Hoboken, N.J., : Wiley-Interscience/John Wiley, c2006"]
[null,null,"ISBN",null,"1-280-40909-6"]
[{"$nulls":4},"9786610409099"]
[{"$nulls":4},"0-470-36036-4"]
[{"$nulls":4},"0-471-73934-0"]
[{"$nulls":4},"0-471-73933-2"]
[null,null,"Descrizione fisica",null,"1 online resource (482 p.)"]
[null,null,"Disciplina",null,"615.321"]
[{"$nulls":4},"615/.321"]
[null,null,"Soggetti",null,"Materia medica, Vegetable"]
[{"$nulls":4},"Pharmaceutical chemistry"]
[{"$nulls":4},"Natural products"]
[{"$nulls":4},"Bioactive compounds"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"MEDICINAL CHEMISTRY OF BIOACTIVE NATURAL PRODUCTS; CONTENTS; Preface; Contributors; 1 The Chemistry and Biology of Epothilones-Lead Structures for the Discovery of Improved Microtubule Inhibitors; 1.1. Introduction; 1.2. Biological Effects of Epo B; 1.2.1 In Vitro Activity; 1.2.2 In Vivo Antitumor Activity; 1.3. Epothilone Analogs and SAR Studies; 1.3.1 Lactam-Based Analogs; 1.3.2 Modifications in the C9-C11 Region; 1.3.3 Modifications of the Epoxide Moiety; 1.3.4 C-26-Modified Analogs; 1.3.5 Side-Chain Modifications; 1.3.6 Aza-Epothilones"]
[{"$nulls":4},"1.4. Pharmacophore Modeling and Conformational Studies1.5. Epothilone Analogs in Clinical Development; 1.6. Conclusions; Acknowledgments; References; 2 The Chemistry and Biology of Vancomycin and Other Glycopeptide Antibiotic Derivatives; 2.1. Introduction; 2.2. Classification of Glycopeptide Antibiotics; 2.3. Mode of Action; 2.4. Glycopeptide Resistance; 2.5. Biosynthesis; 2.6. Total Synthesis; 2.7. Glycopeptides as Chiral Selectors in Chromatography and Capillary Electrophoresis; 2.8. Structural Modifications of "]
[{"$nulls":4},"Glycopeptide Antibiotics and Structure Activity Relationship (SAR) Studies"]
[{"$nulls":4},"2.8.1 Modifications of Glycopeptide Antibiotics2.8.2 Rational Concepts for the Design of Novel Glycopeptides; 2.8.3 Conclusions; Acknowledgment; References; 3 Structure Modifications and Their Influences on Antitumor and Other Related Activities of Taxol and Its Analogs; 3.1. Discovery and Research and Development of Taxol; 3.2. Paclitaxel Analogs Active Against Normal Tumor Cells; 3.2.1 C-13 Side Chain; 3.2.2 A Ring and Its Substitutions; 3.2.3 B Ring and Its Substitutions; 3.2.4 C Ring and Its Substitutions; 3.2.5 D Ring; 3.2.6 Macrocyclic Analogs; 3.2.7 Miscellaneous"]
[{"$nulls":4},"3.3. Exploration on Mechanism of Paclitaxel Related to Tubulin Binding and Quest for Its Pharmacophore3.3.1 Biochemical Mechanism of Paclitaxel Related to Tubulin Binding; 3.3.2 Identification of Bioactive Conformations and Quest for a Pharmacophore for Paclitaxel; 3.4. Natural and Semisynthetic Taxoids Overcoming Multidrug Resistance (MDR); 3.4.1 Structure-Modified Taxoids With Better Activity Toward MDR Tumors; 3.4.2 Nonpaclitaxel-Type Taxoids With MDR Reversal Activities; 3.4.3 Factors Contributing to the Resistance to Paclitaxel"]
[{"$nulls":4},"3.5 Design, Synthesis and Pharmacological Activity of Prodrugs of Paclitaxel3.5.1 Prodrugs Prepared to Improve Water Solubility; 3.5.2 Prodrugs Designed for Enhancing Specificity; 3.6 Other Biological Actions of Paclitaxel; 3.7 New Antimicrotubule Molecules Mimicking Action of Paclitaxel; 3.8 Conclusion; Acknowledgments; References; 4 The Overview of Studies on Huperzine A: A Natural Drug for the Treatment of Alzheimer's Disease; 4.1 Introduction; 4.1.1 Powerful AChEI Originated From Traditional Chinese Medicine; 4.1.2 Alzheimer's Disease; 4.2. Profiles of HA; 4.2.1 Discovery of HA"]
[{"$nulls":4},"4.2.2 Physical Appearance of HA"]
[null,null,null,"Sommario/riassunto","Current discoveries and research into bioactive natural productsMedicinal Chemistry of Bioactive Natural Products provides a much-needed survey of bioactive natural products and their applications in medicinal chemistry. This comprehensive reference features articles by some of the world's leading scientists in the field on discovery, structure elucidation, and elegant synthetic strategies--developed for natural products--with an emphasis on the structure activity relationship of bioactive natural products. The topics have been carefully chosen on the basis of relevance to current rese"]