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[null,"1.","Record Nr.",null,"UNINA9910463096803321"]
[null,null,"Titolo",null,"Advances in anticancer agents in medicinal chemistry . Volume 2 / / edited by Michelle Prudhomme"]
[null,null,"Pubbl/distr/stampa",null,"Sharjah : , : Bentham Science Publishers, , [2013]"]
[{"$nulls":4},"©2013"]
[null,null,"ISBN",null,"1-60805-496-9"]
[null,null,"Descrizione fisica",null,"1 online resource (495 p.)"]
[null,null,"Collana",null,"Advances in anticancer agents in medicinal chemistry ; ; 2"]
[null,null,"Disciplina",null,"616.99"]
[{"$nulls":4},"616.994061"]
[null,null,"Soggetti",null,"Antineoplastic agents"]
[{"$nulls":4},"Pharmaceutical chemistry"]
[{"$nulls":4},"Electronic books."]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Cover; Title; EUL; Contents; Foreword; Preface; List of Contributors; Chapter 01; Chapter 02; Chapter 03; Chapter 04; Chapter 05; Chapter 06; Chapter 07; Chapter 08; Chapter 09; Chapter 10; Index"]
[null,null,null,"Sommario/riassunto","Advances in Anticancer Agents in Medicinal Chemistry is an exciting eBook series comprising a selection of updated articles previously published in the peer-reviewed journal Anti-Cancer Agents in Medicinal Chemistry. The second Volume of this eBook series gathers updated reviews on several classes of molecules exhibiting anticarcinogenic potential as well as some important targets for the development of novel anticancer drugs."]
[null,"2.","Record Nr.",null,"UNINA9910298325103321"]
[null,null,"Titolo",null,"Central Functions of the Ghrelin Receptor / / edited by Jeanelle Portelli, Ilse Smolders"]
[null,null,"Pubbl/distr/stampa",null,"New York, NY : , : Springer New York : , : Imprint : Springer, , 2014"]
[null,null,"ISBN",null,"1-4939-0823-5"]
[null,null,"Edizione",null,"[1st ed. 2014.]"]
[null,null,"Descrizione fisica",null,"1 online resource (217 p.)"]
[null,null,"Collana",null,"The Receptors, , 1048-6909 ; ; 25"]
[null,null,"Disciplina",null,"573.44"]
[null,null,"Soggetti",null,"Neurosciences"]
[{"$nulls":4},"Neurochemistry"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Constitutive activity of the ghrelin receptor -- Homodimerization and heterodimerization of the ghrelin receptor -- The role of the ghrelin receptor in appetite and energy metabolism -- The vagus nerve and ghrelin function -- Central Ghrelin Receptors and Food Intake -- Ghrelin receptors a novel target for obesity -- Ghrelin receptor antagonism as a potential therapeutic target for alcohol use disorders: a preclinical perspective -- Clinical Research on the Ghrelin Axis and Alcohol Consumption -- Ghrelin and Sleep Regulation -- Ghrelin and Memory -- Ghrelin receptors and Epilepsy -- Ghrelin plays a role in various physiological and pathophysiological brain functions -- Ghrelin and Parkinson’s Disease."]
[null,null,null,"Sommario/riassunto","The Ghrelin receptor was identified before its natural ligand ghrelin. This receptor is found both centrally and peripherally, and has been shown to affect various processes, such as food intake, gut motility, memory, glucose and lipid metabolism, cardiovascular performances, reproduction, memory, and immunological responses, amongst others. The functions of the ghrelin receptor in the central nervous system are numerous and are still being explored. In this book we specifically focus on the various roles of the ghrelin receptor in the central nervous system. In a first set of chapters, the book will focus on the discovery and the properties of this intriguing constitutively active G-protein coupled receptor, on its multiple intracellular transduction mechanisms and the various subtypes of the currently known ghrelin receptor complexes. Next, the book will elaborate on the mitochondrial mechanisms regulated by the ghrelin receptor, its role in feeding and drug addictive mechanisms, memory, sleep and arousal. The final "]
[{"$nulls":4},"chapters focus on the potential of this receptor as a target for the treatment of neurological disorders including Parkinson’s disease, epilepsy, anxiety and depression."]