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[null,"1.","Record Nr.",null,"UNINA9910461794503321"]
[null,null,"Autore",null,"Samuels Gayle Brandow"]
[null,null,"Titolo",null,"Enduring roots [[electronic resource] ] : encounters with trees, history, and the American landscape / / Gayle Brandow Samuels"]
[null,null,"Pubbl/distr/stampa",null,"New Brunswick, N.J., : Rutgers University Press, c1999"]
[null,null,"ISBN",null,"0-585-31062-9"]
[{"$nulls":4},"1-283-59320-3"]
[{"$nulls":4},"9786613905659"]
[{"$nulls":4},"0-8135-5608-2"]
[null,null,"Descrizione fisica",null,"1 online resource (210 p.)"]
[null,null,"Collana",null,"Studies in Modern Science, Technology, and the Environment"]
[null,null,"Disciplina",null,"398/.368216"]
[null,null,"Soggetti",null,"Trees - United States"]
[{"$nulls":4},"Trees - Symbolic aspects - United States"]
[{"$nulls":4},"Trees - Environmental aspects - United States"]
[{"$nulls":4},"Landscape assessment - United States"]
[{"$nulls":4},"Electronic books."]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references (p. [177]-189) and index."]
[null,null,"Nota di contenuto",null,"Frontmatter -- Contents -- LIST OF ILLUSTRATIONS -- PREFACE -- ACKNOWLEDGMENTS -- CHAPTER ONE – TAKING ROOT: THE CHARTER OAK -- CHAPTER TWO – FAMILY TREES -- CHAPTER THREE – APPLES: CORE ISSUES -- CHAPTER FOUR – THREE CHERRIES -- CHAPTER FIVE – RETURNING NATIVES -- CHAPTER SIX – THE TREE THAT OWNED ITSELF -- CHAPTER SEVEN – METHUSELAH’S WALK -- NOTES -- BIBLIOGRAPHY -- INDEX -- About the author"]
[null,null,null,"Sommario/riassunto","Trees are the grandest and most beautiful plant creations on earth. From their shade-giving, arching branches and strikingly diverse bark to their complex root systems, trees represent shelter, stability, place, and community as few other living objects can. Enduring Roots tells the stories of historic American trees, including the oak, the apple, the cherry, and the oldest of the world’s trees, the bristlecone pine. These stories speak of our attachment to the land, of our universal and eternal need to leave a legacy, and demonstrate that the landscape is a gift, to be both received and, sometimes, tragically, to be destroyed. Each chapter of this book focuses on a specific tree or group of trees and its relationship to both natural and human history, while exploring "]
[{"$nulls":4},"themes of community, memory, time, and place. Readers learn that colonial farmers planted marker trees near their homes to commemorate auspicious events like the birth of a child, a marriage, or the building of a house. They discover that Benjamin Franklin’s Newtown Pippin apples were made into a pie aboard Captain Cook’s Endeavour while the ship was sailing between Tahiti and New Zealand. They are told the little-known story of how the Japanese flowering cherry became the official tree of our nation’s capital—a tale spanning many decades and involving an international cast of characters. Taken together, these and many other stories provide us with a new ways to interpret the American landscape. “It is my hope,” the author writes, “that this collection will be seen for what it is, a few trees selected from a great forest, and that readers will explore both—the trees and the forest—and find pieces of their own stories in each.”"]
[null,"2.","Record Nr.",null,"UNISA996218390603316"]
[null,null,"Autore",null,"Höltje Hans-Dieter"]
[null,null,"Titolo",null,"Molecular modeling : basic principles and applications / / Hans-Dieter Höltje and Gerd Folkers"]
[null,null,"Pubbl/distr/stampa",null,"Weinheim, Germany ; ; New York, New York : , : John Wiley & Sons, , [1997]"]
[{"$nulls":4},"©1997"]
[null,null,"ISBN",null,"1-281-75846-9"]
[{"$nulls":4},"9786611758462"]
[{"$nulls":4},"3-527-61477-X"]
[{"$nulls":4},"3-527-61476-1"]
[null,null,"Descrizione fisica",null,"1 online resource (209 p.)"]
[null,null,"Collana",null,"Methods and principles in medicinal chemistry ; ; v. 5"]
[null,null,"Disciplina",null,"572/.33/0113"]
[null,null,"Soggetti",null,"Molecules - Models - Computer simulation"]
[{"$nulls":4},"Ligand binding (Biochemistry) - Computer simulation"]
[{"$nulls":4},"Biomolecules - Structure - Computer simulation"]
[{"$nulls":4},"Drugs - Design - Computer simulation"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Molecular Modeling; Preface; A Personal Foreword; Contents; 1 Introduction; 1.1 Modern History of Molecular Modeling; 1.2 Do Today's Molecular Modeling Methods Illustrate only the Lukretian World?; 1.3 What are Models Used for?; 1.4 Molecular Modeling Uses All FourTypes for Model Building; 1.5 The Final Step is Design; 1.6 The Scope of the Book; 2 Small Molecules; 2.1 Generation of 3D Coordinates; 2.1.1 Crystal Data; 2.1.2 Fragment Libraries; 2.1.3 Sketch Approach; 2.2 Computational Tools for Geometry Optimization; 2.2.1 Force Fields; 2.2.2 Geometry Optimization"]
[{"$nulls":4},"2.2.3 Energy-Minimizing Procedures2.2.3.1 Steepest Descent Minimizer; 2.2.3.2 Conjugate Gradient Method; 2.2.3.3 Newton-Raphson Minimizer; 2.2.4 Use of Charges, Solvation Effects; 2.2.5 Quantum Mechanical Methods; 2.2.5.1 Ab initio Methods; 2.2.5.2 Semiempirical Molecular Orbital Methods; 2.3 Conformational Analysis; 2.3.1 Conformational Analysis Using Systematic Search Procedures; 2.3.2 Conformational Analysis Using Monte Carlo Methods; 2.3.3 Conformational Analysis Using Molecular Dynamics; 2.4 Determination of Molecular Interaction Potentials"]
[{"$nulls":4},"2.4.1 Molecular Electrostatic Potentials (MEPs)2.4.1.1 Methods for Calculating Atomic Point Charges; 2.4.1.2 Methods for Generating MEPs; 2.4.2 Molecular Interaction Fields; 2.4.2.1 Calculation of GRID Fields; 2.4.2.2 How GRID Fields can be Exploited; 2.4.2.3 Use of Chemometrics:The CoMFA Method; 2.4.3 Hydrophobic Interactions; 2.4.3.1 Log P as a Measure of Lipophilicity; 2.4.3.2 The Hydropathic Field; 2.4.3.3 Display of Properties on a Molecular Surface; 2.5 Pharmacophore Identification; 2.5.1 Molecules to be Matched; 2.5.2 Atom-by-Atom Superposition; 2.5.3 Superposition of Molecular Fields"]
[{"$nulls":4},"2.6 The Use of Data Bants2.6.1 Conversion of 2D Structural Data into 3D Form; 2.6.2 3D Searching; 3 Example for Small Molecule Modeling: Serotonin Receptor Ligands; 3.1 Definition of the Serotoninergic Pharmacophore; 3.2 The Molecular Interaction Field; 3.3 Construction of a 5-HT 2a Receptor Binding Site Model; 3.4 Calculation of Interaction Energies; 3.5 Validation of the Model; 4 Introduction to Protein Modeling; 4.1 Where and How to get Information on Proteins; 4.2 Terminology and Principles of Protein Structure; 4.2.1 Conformational Properties of Proteins"]
[{"$nulls":4},"4.2.2 Types of Secondary Structural Elements4.2.2.1 The α-Helix; 4.2.2.2 The β-Sheet; 4.2.2.3 Turns; 4.2.3 Homologous Proteins; 4.3 Knowledge-Based Protein Modeling; 4.3.1 Procedures for Sequence Alignments; 4.3.2 Determination and Generation of Structurally Conserved Regions (SCRs); 4.3.3 Construction of Structurally Variable Regions (SVRs); 4.3.4 Side Chain Modeling; 4.3.5 Distance Geometry Approach; 4.3.6 Secondary Structure Prediction; 4.3.7 Energy-Based Modeling Methods; 4.4 Optimization Procedures - Model Refinement - Molecular Dynamics; 4.4.1 Force Fields for Protein Modeling"]
[{"$nulls":4},"4.4.2 Geometry Optimization"]
[null,null,null,"Sommario/riassunto","Written by experienced experts in molecular modeling, this books describes the basics to the extent that is necessary if one wants to be able to reliably judge the results from molecular modeling calculations. Its main objective is the description of the various pitfalls to be avoided. Without unnecessary overhead it leads the reader from simple calculations on small molecules to the modeling of proteins and other relevant biomolecules.A textbook for beginners as well as an invaluable reference for all those dealing with molecular modeling in their daily work!"]