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[null,"1.","Record Nr.",null,"UNINA990006235190403321"]
[null,null,"Autore",null,"Galatello Adamo, Andrea"]
[null,null,"Titolo",null,"Liberalismi : la cultura del giovane Vittorio Emanuele Orlando / Andrea Galatello-Adamo"]
[null,null,"Pubbl/distr/stampa",null,"Torino : Giappichelli, 1995"]
[null,null,"ISBN",null,"88-348-4251-0"]
[null,null,"Descrizione fisica",null,"174 p. ; 17 cm"]
[null,null,"Disciplina",null,"320.51"]
[{"$nulls":4},"320.512092"]
[{"$nulls":4},"195"]
[null,null,"Locazione",null,"FGBC"]
[{"$nulls":4},"DDA"]
[{"$nulls":4},"DFD"]
[{"$nulls":4},"FSPBC"]
[null,null,"Collocazione",null,"XI D 736"]
[{"$nulls":4},"VI L 991"]
[{"$nulls":4},"XI C G 2(5)"]
[{"$nulls":4},"XI C G 2(6)"]
[{"$nulls":4},"XI C G 2(7)"]
[{"$nulls":4},"XI C G 2(8)"]
[{"$nulls":4},"XII A 1263"]
[{"$nulls":4},"XII A 1256"]
[null,null,"Lingua di pubblicazione",null,"Italiano"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,"2.","Record Nr.",null,"UNINA9910455854803321"]
[null,null,"Titolo",null,"Regulation through litigation [[electronic resource] /] / W. Kip Viscusi, editor"]
[null,null,"Pubbl/distr/stampa",null,"Washington, D.C., : AEI-Brookings Joint Center for Regulatory Studies, c2002"]
[null,null,"ISBN",null,"0-8157-9885-7"]
[null,null,"Descrizione fisica",null,"1 online resource (381 p.)"]
[null,null,"Disciplina",null,"347.73/53"]
[null,null,"Soggetti",null,"Citizen suits (Civil procedure) - United States"]
[{"$nulls":4},"Delegated legislation - United States"]
[{"$nulls":4},"Class actions (Civil procedure) - United States"]
[{"$nulls":4},"Public policy (Law) - United States"]
[{"$nulls":4},"Electronic books."]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Bibliographic Level Mode of Issuance: Monograph"]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Overview/ W. Kip Viscusi -- Tobacco : regulation and taxation through litigation/ W. Kip Viscusi ; comment by John E. Calfee-- Litigation as regulation : firearms/ Philip J. Cook and Jens Ludwig ; comment by Jim Leitzel-- Litigating lead-based paint hazards/ Randall Lutter and Elizabeth Mader ; comment by Thomas J. Kniesner-- Breast implants : regulation, litigation, and science/ Joni Hersch ; comment by Peter Schuck-- Malpractice pressure, managed care, and physician behavior/ Daniel P. Kessler and Mark B. McClellan ; comment by Patricia Danzon-- The insurance effects of regulation by litigation/ Kenneth S. Abraham ; comment by J. David Cummins-- The regulatory advantage of class action/ David Rosenberg ; comment by James Wootton-- Implications for legal reform/ Richard A. Epstein ; comment by Gary T. Schwartz."]
[null,"3.","Record Nr.",null,"UNINA9910458853903321"]
[null,null,"Autore",null,"Peace Karl E. <1941, >"]
[null,null,"Titolo",null,"Clinical trial methodology / / Karl E. Peace, Ding-Geng (Din) Chen"]
[null,null,"Pubbl/distr/stampa",null,"Boca Raton : , : Chapman and Hall/CRC Press, , 2011"]
[null,null,"ISBN",null,"0-429-14207-2"]
[{"$nulls":4},"1-58488-918-7"]
[null,null,"Descrizione fisica",null,"1 online resource (422 p.)"]
[null,null,"Collana",null,"Chapman & Hall/CRC biostatistics series ; ; 35"]
[null,null,"Disciplina",null,"615.5072/4"]
[null,null,"Soggetti",null,"Clinical trials"]
[{"$nulls":4},"Drugs - Testing"]
[{"$nulls":4},"Electronic books."]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Front cover; Contents; Preface; Chapter 1: Overview of Clinical Trial Methodology; Chapter 2: Overview of the Drug Development Processand Regulation of Clinical Trials; Chapter 3: Ethical Considerations in the Designand Conduct of Clinical Trials; Chapter 4: Sample Size Considerations in ClinicalTrials Pre-Market Approval; Chapter 5: Sequential, Group Sequential, StochasticCurtailment, and Adaptive DesignProcedures in Clinical Trials; Chapter 6: Biostatistical Aspects of the Protocol; Chapter 7: The Statistical Analysis Plan; Chapter 8: Pooling of Data from Multicenter Clinical Trials"]
[{"$nulls":4},"Chapter 9: Validity of Statistical InferenceChapter 10: Bioequivalence Clinical Trials; Chapter 11: Dose and Frequency Determinationfrom Phase II Clinical Trials in StressTest-Induced Angina; Chapter 12: Confirmation of Clinically Optimal Dosingin the Treatment of Duodenal Ulcers:A Phase III Dose Comparison Trial; Chapter 13: Pivotal Proof-of-Efficacy Clinical Trialsin the Prevention of NANSAID-InducedGastric Ulceration; Chapter 14: Clinical Trials in the Treatmentof Alzheimer's Disease Based uponEnrichment Designs; Chapter 15: A Clinical Trial to Establish Reductionof CHD Risk"]
[{"$nulls":4},"Chapter 16: Pivotal Proof-of-Efficacy Clinical Trialsin the Treatment of Panic DisorderChapter 17: Combination Clinical Trials; Chapter 18: Monitoring Clinical Trials for Adverse Events; Index; Back cover"]
[null,null,null,"Sommario/riassunto","Now viewed as its own scientific discipline, clinical trial methodology encompasses the methods required for the protection of participants in a clinical trial and the methods necessary to provide a valid inference "]
[{"$nulls":4},"about the objective of the trial. Drawing from the authors courses on the subject as well as the first authors more than 30 years working in the pharmaceutical industry, Clinical Trial Methodology emphasizes the importance of statistical thinking in clinical research and presents the methodology as a key component of clinical research. From ethical issues and sample size considerations to adaptive design procedures and statistical analysis, the book first covers the methodology that spans every clinical trial regardless of the area of application. Crucial to the generic drug industry, bioequivalence clinical trials are then discussed. The authors describe a parallel bioequivalence clinical trial of six formulations incorporating group sequential procedures that permit sample size re-estimation. The final chapters incorporate real-world case studies of clinical trials from the authors own experiences. These examples include a landmark Phase III clinical trial involving the treatment of duodenal ulcers and Phase III clinical trials that contributed to the first drug approved for the treatment of Alzheimers disease. Aided by the U.S. FDA, the U.S. National Institutes of Health, the pharmaceutical industry, and academia, the area of clinical trial methodology has evolved over the last six decades into a scientific discipline. This guide explores the processes essential for developing and conducting a quality clinical trial protocol and providing quality data collection, biostatistical analyses, and a clinical study report, all while maintaining the highest standards of ethics and excellence--Provided by publisher."]
[null,"4.","Record Nr.",null,"UNINA9910818181603321"]
[null,null,"Autore",null,"Tikhomirov Viatcheslav V."]
[null,null,"Titolo",null,"Hydrogeochemistry fundamentals and advances . Volume 1 Groundwater composition and chemistry / / Viatcheslav V. Tikhomirov"]
[null,null,"Pubbl/distr/stampa",null,"Hoboken, New Jersey : , : Scrivener Publishing, , 2016"]
[{"$nulls":4},"©2016"]
[null,null,"ISBN",null,"1-119-16044-8"]
[{"$nulls":4},"1-119-16042-1"]
[null,null,"Descrizione fisica",null,"1 online resource (308 p.)"]
[null,null,"Disciplina",null,"551.490154"]
[null,null,"Soggetti",null,"Water chemistry"]
[{"$nulls":4},"Hydrogeology"]
[{"$nulls":4},"Groundwater"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Volume 1: Groundwater Composition and Chemistry"]