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[null,"1.","Record Nr.",null,"UNINA9910455297903321"]
[null,null,"Autore",null,"Hawley R. Scott"]
[null,null,"Titolo",null,"Advanced genetic analysis [[electronic resource] ] : finding meaning in a genome / / R. Scott Hawley and Michelle Y. Walker"]
[null,null,"Pubbl/distr/stampa",null,"Malden, Mass., : Blackwell Pub., c2003"]
[null,null,"ISBN",null,"1-282-11830-7"]
[{"$nulls":4},"9786612118302"]
[{"$nulls":4},"1-4443-1308-8"]
[null,null,"Descrizione fisica",null,"1 online resource (257 p.)"]
[null,null,"Disciplina",null,"576.5/072"]
[null,null,"Soggetti",null,"Genetics - Research - Methodology"]
[{"$nulls":4},"Electronic books."]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references (p. [220]-235) and indexes."]
[null,null,"Nota di contenuto",null,"Advanced Genetic Analysis; Contents; Preface; Introduction; 1: Mutation; 1.1 Types of mutations; 1.1.1 Muller's classification of mutants; 1.1.2 Modern mutant terminology; 1.1.3 DNA-level terminology; 1.2 Dominance and recessivity; 1.2.1 Dominance and recessivity at the level of the cell; 1.2.2 Difficulties in applying the terms \"\"dominant\"\" and \"\"recessive\"\" to sex-linked mutants; 1.3 The genetic utility of dominant and recessive mutants; Summary; Gallery of model organisms; 1.1 Our favorite organism: Drosophila melanogaster; 1.2 Our second favorite organism: Saccharomyces cerevisiae"]
[{"$nulls":4},"1.3 Our third favorite organism: Caenorhabditis elegans1.4 Our new favorite organism: zebrafish; 1.5 Phage lambda; 1.6 Phage T4; 1.7 Arabidopsis thaliana; 1.8 Mus musculus (the mouse); 2: Mutant hunts; 2.1 Why look for new mutant?; 2.1.1 Reason 1: To identify genes required for a specific biological process; Box 2.1 A screen for embryonic lethal mutations in Drosophila; Box 2.2 The balancer chromosome; 2.1.2 Reason 2: To isolate more mutations in a specific gene of interest; Box 2.3 A screen for sex-linked lethal mutations in Drosophila"]
[{"$nulls":4},"2.1.3 Reason 3: To obtain mutation tools for structure-function analysis2.1.4 Reason 4: To isolate mutations in a gene so far identified only by molecular approaches; 2.2 Mutagenesis and mutational mechanisms; 2.2.1 Method 1: Ionizing radiation (usually X-rays and gamma-rays); 2.2.2 Method 2: Chemical mutagens; 2.2.3 Method 3: "]
[{"$nulls":4},"Transposons as mutagens; 2.2.4 Method 4: Targeted gene disruption (a variant on transposon mutagenesis); Box 2.4 Making phenocopies by RNAi and co-suppression; 2.3 What phenotype should you screen (or select) for?; 2.4 Actually getting started"]
[{"$nulls":4},"2.4.1 Your starting material2.4.2 Pilot screens; 2.4.3 Keeping too many, keeping too few; 2.4.4 How many mutants is enough?; Summary; Box 2.5 Reviews of mutant isolation schemes and techniques in various organisms; 3: The complementation test; 3.1 The essence of the complementation test; Box 3.1 A more rigorous definition of the complementation test; Box 3.2 An example of using the complementation test in yeast; 3.2 Rules for using the complementation test; Box 3.3 Transformation rescue is a variant of the complementation test"]
[{"$nulls":4},"Box 3.4 One method for determining whether or not a dominant mutation is an allele of a given gene, or how to make dominants into recessives by pseudo-reversion3.3 How might the complementation test lie to you?; 3.4 Second-site non-complementation (SSNC) (non-allelic non-complementation); 3.4.1 Type I SSNC (poisonous interactions): the interaction is allele-specific at both loci; Box 3.5 Pairing-dependent complementation: transvection; Box 3.6 Synthetic lethality and genetic buffering; 3.4.2 Type 2 SSNC (sequestration): the interaction is allele-specific at one locus"]
[{"$nulls":4},"3.4.3 Type 3 SSNC (combined haplo-insufficiency): the interaction is allele-independent at both loci"]
[null,null,null,"Sommario/riassunto","Advanced Genetic Analysis brings a state-of-the-art, exciting new approach to genetic analysis. Focusing on the underlying principles of modern genetic analysis, this book provides the 'how' and 'why' of the essential analytical tools needed. The author's vibrant, accessible style provides an easy guide to difficult genetic concepts, from mutation and gene function to gene mapping and chromosome segregation. Throughout, a balanced range of model organisms and timely examples are used to illustrate the theoretical basics. Basic principles - Focuses students attention on t"]
[null,"2.","Record Nr.",null,"UNINA9910790990603321"]
[null,null,"Autore",null,"Zamparelli Roberto"]
[null,null,"Titolo",null,"Layers in the determiner phrase / / Roberto Zamparelli"]
[null,null,"Pubbl/distr/stampa",null,"London : , : Routledge, , 2013"]
[null,null,"ISBN",null,"1-138-97952-X"]
[{"$nulls":4},"1-315-05436-1"]
[{"$nulls":4},"1-135-71393-6"]
[{"$nulls":4},"1-135-71386-3"]
[null,null,"Descrizione fisica",null,"1 online resource (331 p.)"]
[null,null,"Collana",null,"Outstanding dissertations in linguistics"]
[null,null,"Disciplina",null,"415"]
[null,null,"Soggetti",null,"Grammar, Comparative and general - Determiners"]
[{"$nulls":4},"Grammar, Comparative and general - Noun phrase"]
[{"$nulls":4},"Grammar, Comparative and general - Existential constructions"]
[{"$nulls":4},"Semantics"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","First published 2000 by Garland Publishing Inc."]
[{"$nulls":4},"Originally presented as the author's thesis, Rochester."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Cover; Outstanding Dissertations in Linguistics; Title Page; Copyright Page; Dedication; Acknowledgments; Abstract; Table of Contents; Introduction; 1 Preliminaries; 1.1 Semantics preliminaries: type-shifting; 1.1.1 Problems for invisible type-shifting operators; 1.1.2 Type-shifting and specificity; 1.1.3 Quantifiers: e-type at LF; 1.1.4 Introduction to the layer system; 1.1.4.1 The PDP layer; 1.1.4.2 The KIP Layer; 1.1.5 The semantic contribution; 1.2 Syntactic preliminaries: the DP hypothesis; 1.2.1 Functional projections; 1.2.2 N-movement"]
[{"$nulls":4},"1.2.3 The relative position of N and attributive adjectives1.2.4 Attributive adjectives in predicative position; 1.3 What this dissertation is not about; 1.4 Data; 1.5 Terminological conventions; 1.6 Overview of the contents; Notes; 2 The Strong/Weak Distinction and the Definiteness Effect; 2.1 Introduction; 2.2 The 'strong/weak' distinction; 2.2.1 Existential Sentences; 2.2.2 Numerals in ES; 2.3 Treatments of the Definiteness Effect; 2.3.1 Milsark (1977); 2.3.2 ES in Generalized Quantifier Theory; 2.3.2.1 Barwise&Cooper (1981); 2.3.2.2 Keenan (1987); 2.3.3 Heim on WHs in ES"]
[{"$nulls":4},"2.3.4 Presuppositional Set Theories of ES2.3.4.1 The \"A Certain PN\" Construction; 2.3.5 McNally (1992); 2.3.5.1 Predicate nominals and ES-"]
[{"$nulls":4},"internal noun phrases: some similarities; 2.3.5.2 A split analysis of DE; 2.3.5.3 Semantics of McNally (1992); 2.3.6 Criticism of McNally's account; 2.3.6.1 Two \"be\"?; 2.3.6.2 On the subkind reading for common nouns; 2.3.6.3 On the sortal uniformity of ES-internal noun phrase; 2.3.6.4 Italian ES: locatives and existentials; 2.3.6.5 Summary; Notes; 3 The kind-construction and its relatives; 3.1 Two orders of kind-nouns"]
[{"$nulls":4},"3.2 The family of 'pivotal' constructions3.2.1 Invertibility; 3.2.2 Agreement facts; 3.3 Copular sentences; 3.3.1 Moro's theory of copular sentences; 3.3.2 On empty pro-predicates; 3.4 The microstructure of the kind-construction; 3.4.1 Predicate and Argument in the kind-construction; 3.4.2 Identification with KIP; 3.5 Extraction possibilities; 3.5.1 Summary; 3.5.2 Reasons for raising; 3.5.2.1 Williams' puzzle revisited; 3.6 Chapter conclusions; Notes; 4 The layers of DP; 4.1 Introduction; 4.1.1 Some general principles; 4.1.2 The structure of weak argumental noun phrases"]
[{"$nulls":4},"4.1.3 Weak quantifiers as adjectives: the problem of negation4.1.4 On the absence of multiple determiners; 4.2 Evidence for three levels; 4.2.1 Coordination and bare predicates; 4.2.1.1 The interpretation of predicative KIP; 4.2.2 Predicative possessives; 4.2.3 Ne; 4.2.3.1 On unifying Ne; 4.2.4 Quantifiers under indefinites in Italian; 4.2.4.1 (Il) quale; 4.2.4.2 (Un) qualche; 4.2.5 Conclusions; 4.3 Spec/head licensing; 4.3.1 AdjP raising and predication; 4.3.2 On some differences between SDP and KIP; 4.4 The SDmax level; 4.4.1 Noun movement to SDmax; 4.4.2 Longobardi's (1994) theory"]
[{"$nulls":4},"4.4.3 A minimalist implementation"]
[null,null,null,"Sommario/riassunto","The main topic of this work is the interaction between syntactic structure and meanin within the noun phrase, with data drwn primarily from English and Italian."]