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[null,"1.","Record Nr.",null,"UNINA9910451662903321"]
[null,null,"Titolo",null,"Parkinson's disease [[electronic resource] ] : diagnosis and clinical management / / edited by Stewart A. Factor, William J. Weiner"]
[null,null,"Pubbl/distr/stampa",null,"New York, : Demos, c2008"]
[null,null,"ISBN",null,"1-281-97519-2"]
[{"$nulls":4},"9786611975197"]
[{"$nulls":4},"1-934559-87-3"]
[null,null,"Edizione",null,"[2nd ed., rev. and updated.]"]
[null,null,"Descrizione fisica",null,"1 online resource (858 p.)"]
[null,null,"Disciplina",null,"616.8/33"]
[null,null,"Soggetti",null,"Parkinson's disease"]
[{"$nulls":4},"Electronic books."]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Cover; Title Page; Table of Contents; Foreword; Preface; Acknowledgments; Contributors; 1. James Parkinson: The Man and the Essay; 2. Paralysis Agitans in the Nineteenth Century; 3. Charcot and Parkinson's Disease; 4. Timeline of Parkinson's Disease History Since 1900; 5. Epidemiology; 6. Cardinal Features of Early Parkinson's Disease; 7. Gait Disturbances; 8. Sensory Symptoms; 9. Voice, Speech, and Swallowing Disorders; 10. Gastrointestinal Features; 11. Autonomic Dysfunction; 12. Sleep Disorders; 13. Natural History; 14. Clinical Rating Scales; 15. Dementia; 16. Depression"]
[{"$nulls":4},"17. Anxiety and Panic18. Apathy and Amotivation; 19. Impulse-control Disorders; 20. Neuropathology; 21. Neurochemistry; 22. Basal Ganglia: Anatomy and Physiology; 23. Dopamine Receptor Diversity; 24. Status of Biological Markers; 25. Positron Emission Tomography; 26. Single Photon Emission Computed Tomography; 27. Magnetic Resonance Imaging; 28. Controversies in Neuroimaging; 29. Animal Models; 30. Pathogenesis: Oxidative Stress, Mitochondrial Dysfunction, and Excitotoxicity; 31. The Concept and Mechanisms of Programmed Cell Death; 32. Protein Aggregation"]
[{"$nulls":4},"33. Etiology: The Role of Environment and Genetics34. The Impact of MPTP on Parkinson's Disease Research: Past, Present, and Future; 35. Rotenone and Other Toxins; 36. Inflammation; 37. Genetics; 38. Levodopa: A Pharmacologic Miracle Four Decades Later; 39. Amantadine and Anticholinergics; 40. Monoamine Oxidase Inhibitors; "]
[{"$nulls":4},"41. Dopamine Agonists; 42. Catechol-O-Methyltransferase Inhibitors; 43. Excitatory Amino Acid Antagonists; 44. Adenosine A2A Receptor Antagonists; 45. Complementary and Alternative Medicine; 46. Motor Fluctuations and Dyskinesia; 47. Fluctuations of Nonmotor Symptoms"]
[{"$nulls":4},"48. Psychosis and Other Behaviors49. Treatment of Dementia; 50. Status of Neuroprotective Therapies; 51. Symptomatic Treatment Approaches for Early Parkinson's Disease; 52. Progress in Gene Therapy; 53. Genetic Testing; 54. Deep Brain Stimulation; 55. Neural Transplantation: Yesterday, Today, and Tomorrow; 56. Stereotactic Pallidotomy and Thalamotomy; 57. Parkinson's-plus Disorders; 58. Symptomatic Parkinsonism; 59. Outcome Measures; 60. Family Caregiving; 61. Economics; 62. Driving; 63. The Patient's Perspective; Index"]
[null,null,null,"Sommario/riassunto","Parkinson's disease (PD) is the second most common neurodegenerative disease in the world. Still the only major text on the subject, the completely revised and updated second edition of Parkinson's Disease: Diagnosis and Clinical Management comes at a time when specialists have made important advances in our understanding of the etiology, pathogenesis, investigation, and management of Parkinson's disease."]