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[null,"1.","Record Nr.",null,"UNICAMPANIAVAN0000838"]
[null,null,"Titolo",null,"Statistica : edita, sotto gli auspici delle Università di Bologna, Padova e Palermo, dalla Scuola di Perfezionamento in discipline corporative dell'Università di Ferrara"]
[null,null,"Pubbl/distr/stampa",null,"Ferrara, : S.A.T.E., 1941-"]
[null,null,"ISSN",null,"0390-590X"]
[null,null,"Descrizione fisica",null,"volumi ; 24 cm"]
[null,null,"Lingua di pubblicazione",null,"Italiano"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Periodico"]
[null,null,null,"Note generali","Complemento del titolo varia: rivista trimestrale. - Editore varia: Bologna : Clueb. - Continuazione di: Supplemento statistico ai Nuovi problemi di politica, storia ed economia"]
[null,"2.","Record Nr.",null,"UNINA9910437620103321"]
[null,null,"Autore",null,"Castellano Immacolata"]
[null,null,"Titolo",null,"Gamma-glutamyl transpeptidases : structure and function / / by Immacolata Castellano, Antonello Merlino"]
[null,null,"Pubbl/distr/stampa",null,"Basel, : Springer, 2013"]
[null,null,"ISBN",null,"3-0348-0682-5"]
[null,null,"Edizione",null,"[1st ed. 2013.]"]
[null,null,"Descrizione fisica",null,"1 online resource (65 p.)"]
[null,null,"Collana",null,"SpringerBriefs in biochemistry and molecular biology"]
[null,null,"Disciplina",null,"612.0151"]
[null,null,"Soggetti",null,"Peptidase"]
[{"$nulls":4},"Transpeptidation"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references."]
[null,null,"Nota di contenuto",null," 1 Introduction -- 2 Occurrence, genes and gene expression -- 3 Structure and function of γ-GTs -- 4 Autoprocessing and reaction mechanism of γ-GTs -- 5 γ-GT in bioclinical -- 6 γ-GTs: biotechnological and biomedical applications -- 7 Conclusions -- References."]
[null,null,null,"Sommario/riassunto"," Gamma-Glutamyl Transpeptidases (γ-GTs) are members of the N-terminal nucleophile hydrolase superfamily, enzymes that cleave the γ-glutamyl amide bond of glutathione to liberate cysteinylglycine. The released γ-glutamyl group can be transferred to water (hydrolysis) or to amino acids or short peptides (transpeptidation). γ-GT plays a key role in the gamma glutamyl cycle by regulating the cellular levels of the antioxidant glutathione, hence it is a critical enzyme in maintaining cellular redox homeostasis.γ-GT is upregulated during inflammation and in several human tumors, and it is involved in many physiological disorders related to oxidative stress, such as Parkinson’s disease and diabetes. Furthermore, this enzyme is used as a marker of liver disease and cancer. This book covers current knowledge about the structure-function relationship of γ-GTs and gives information about applications of γ-GTs in different fields ranging from clinical biochemistry to biotechnology and biomedicine."]