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[null,"1.","Record Nr.",null,"UNINA9910427669303321"]
[null,null,"Autore",null,"Brombal Luca"]
[null,null,"Titolo",null,"X-Ray Phase-Contrast Tomography : Underlying Physics and Developments for Breast Imaging / / by Luca Brombal"]
[null,null,"Pubbl/distr/stampa",null,"Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020"]
[null,null,"ISBN",null,"3-030-60433-0"]
[null,null,"Edizione",null,"[1st ed. 2020.]"]
[null,null,"Descrizione fisica",null,"1 online resource (XIII, 140 p. 68 illus., 53 illus. in color.)"]
[null,null,"Collana",null,"Springer Theses, Recognizing Outstanding Ph.D. Research, , 2190-5061"]
[null,null,"Disciplina",null,"616.9944906"]
[null,null,"Soggetti",null,"Medical physics"]
[{"$nulls":4},"Cancer"]
[{"$nulls":4},"Medical screening"]
[{"$nulls":4},"Radiography, Medical"]
[{"$nulls":4},"Synchrotrons"]
[{"$nulls":4},"Cancer - Imaging"]
[{"$nulls":4},"Medical Physics"]
[{"$nulls":4},"Cancer Screening"]
[{"$nulls":4},"Radiography"]
[{"$nulls":4},"Synchrotron Techniques"]
[{"$nulls":4},"Cancer Imaging"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,"Nota di contenuto",null,"Introduction -- Physics of Propagation-based X-ray Tomography -- Propagation-based Breast CT and SYRMA-3D Project -- Detector and Pre-processing -- Experimental Optimization of Propagation-based BCT -- Three-Dimensional Imaging: A Clinically Oriented Focus -- Do We Need Clinical Applications in Synchrotrons? -- Conclusions."]
[null,null,null,"Sommario/riassunto","X-ray imaging is a corner stone of breast cancer diagnosis. By exploiting the phase shift of X-rays rather than their attenuation, phase-contrast tomography has the potential to dramatically increase the visibility of small and low contrast features, thus leading to better diagnosis. This thesis presents research on the first synchrotron-based project developing a clinical phase-contrast breast computed tomography (CT) setup at Elettra, the Italian Syncrotron Radiation Facility. This book includes a comprehensive theoretical background on "]
[{"$nulls":4},"propagation-based phase-contrast imaging, exploring and extending the most recent image formation models. Along with theory, many practical implementation and optimization issues, ranging from detector-specific processing to setup geometry, are tackled on the basis of a large number of experimental evidences. Most of the modelling results and data analysis have general validity, being a valuable framework for optimization of phase-contrast setups. Results obtained at synchrotron are also compared with \"real world\" laboratory sources: both a first-of-its-kind comparison with one of the few hospital breast CT systems and a state-of-the-art implementation of monochromatic phase-contrast micro-tomography with a conventional rotating anode source are presented. On a more general level, this work sheds a light on the importance of synchrotron-based clinical programs, which are key to trigger the long-anticipated transition of phase-contrast imaging from synchrotrons to hospitals. ."]