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[null,"1.","Record Nr.",null,"UNISA996389539203316"]
[null,null,"Autore",null,"Standish Arthur <fl. 1611-1613.>"]
[null,null,"Titolo",null,"New directions of experience to the Commons complaint by the incouragement of the Kings most excellent Maiesty, as may appeare, for the planting of timber and fire-wood [[electronic resource] ] : With a neere estimation what millions of acres the kingdome doth containe; what acres is waste ground, whereon little profit for this purpose will arise. :  What millions hath bin woods, and bushy grounds, what acres are woods, and in how many acres so much timber will be contained, as will maintaine the kingdome for all vses for euer. : And how as great store of fire-wood may be raised, as may plentifully maintaine the kingdome for all purposes, without losse of ground; so as within thirty yeares all spring-woods may be conuerted to tillage and pasture. / / Inuented by Arthur Standish"]
[null,null,"Pubbl/distr/stampa",null,"[S.l., : N. Okes], Anno Domini. MDCXIII. [1613]"]
[null,null,"Descrizione fisica",null,"[4], 36 p. : coat of arms"]
[null,null,"Soggetti",null,"Fuelwood crops - Great Britain"]
[{"$nulls":4},"Tree crops - Great Britain"]
[{"$nulls":4},"Reforestation - Great Britain"]
[{"$nulls":4},"Forests and forestry - Great Britain"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Royal arms (p. [3]), head-pieces, tail-pieces, initials."]
[{"$nulls":4},"Publisher suggested by STC (2nd ed.)."]
[{"$nulls":4},"Signatures: A-C⁴ D² E⁴ F²."]
[{"$nulls":4},"Includes 'A second direction, for the present encreasing of firewood, agreeable to the nature of this age, 1613. February 1.' -- p. 25-36."]
[{"$nulls":4},"Reproduction of original in: National Library of Scotland."]
[null,null,null,"Sommario/riassunto","eebo-0097"]
[null,"2.","Record Nr.",null,"UNINA9910383156303321"]
[null,null,"Autore",null,"Kojima Hajime"]
[null,null,"Titolo",null,"Alternatives to Animal Testing : Proceedings of Asian Congress 2016 / / edited by Hajime Kojima, Troy Seidle, Horst Spielmann"]
[null,null,"Pubbl/distr/stampa",null,"Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2019"]
[null,null,"ISBN",null,"981-13-2447-6"]
[null,null,"Edizione",null,"[1st ed. 2019.]"]
[null,null,"Descrizione fisica",null,"1 online resource (VI, 130 p. 46 illus., 39 illus. in color.)"]
[null,null,"Collana",null,"Biomedical and Life Sciences Series"]
[null,null,"Classificazione",null,"MED071000MED089000SCI007000"]
[null,null,"Disciplina",null,"615"]
[null,null,"Soggetti",null,"Pharmacology"]
[{"$nulls":4},"Biochemistry"]
[{"$nulls":4},"Animal welfare - Moral and ethical aspects"]
[{"$nulls":4},"Animal Ethics"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,"Nota di contenuto",null,"1. Zebrafish, Danio rerio as a replacement alternative model useful in CKDu experiments -- 2. Testing Method Development and Validation for In Vitro Skin Irritation Testing (SIT) by Using Reconstructed Human Epidermis (RhE) Skin Equivalent - EPiTR -- 3. Development the technique for the Preparation and Characterization of Reconstructed Human Epidermis (RHE) -- 4. Alternative Research (3Rs) in the World, Asia and Japan -- 5. Approaches to Reducing Animal Use for Acute Toxicity Testing: Retrospective Analyses of Pesticide Data -- 6. Progress in deleting the 1-year dog study for the safety assessment of pesticides -- 7. Cosmetic regulation and alternatives to animal experimentation in India -- 8. Guidance on the Use of Alternative Test Methods for the Safety Assessment of Cosmetics and Quasi-Drugs -- 9. Alternatives and Refinement for Animal Experimentation in Cancer Research -- 10. 3Rs in quality control of human vaccines: opportunities and barriers -- 11. The Use of Adverse Outcome Pathways (AOPs) to Support Chemical Safety Decisions within the Context of Integrated Approaches to Testing and Assessment (IATA) -- 12. Mechanism-based evaluation system for hepato- and nephrotoxicity or carcinogenicity using omics technology -- 13. Alternative methods for developmental toxicity testing using mouse ESCs -- 14. Futuristic approach to alternative model organisms: Hydra stakes its claim -- 15. The Lush Prize and Young Researcher Asia Awards 2016."]
[null,null,null,"Sommario/riassunto","This open access book presents recent advances in the pure sciences "]
[{"$nulls":4},"that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs. The book is based on the most informative contributions delivered at the Asian Congress 2016 on Alternatives and Animal Use in the Life Sciences. It will be of value for those working in R&D, for graduate students, and for educators in various fields, including the pharmaceutical and cosmetic sciences, pharmacology, toxicology, and animal welfare. The free, open access distribution of Alternatives to Animal Testing is enabled by the Creative Commons Attribution license in International version 4: CC BY 4.0."]