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[null,"1.","Record Nr.",null,"UNINA9910353336203321"]
[null,null,"Autore",null,"Rochwert-Zuili Patricia"]
[null,null,"Titolo",null,"Crónica de Castilla : Édition et présentation"]
[null,null,"Pubbl/distr/stampa",null,"Paris, : e-Spania Books, 2010"]
[null,null,"ISBN",null,"2-919448-07-2"]
[null,null,"Descrizione fisica",null,"1 online resource (388 p.)"]
[null,null,"Soggetti",null,"Arts &amp; Humanities"]
[{"$nulls":4},"Literature&#44; Romance"]
[{"$nulls":4},"chevalerie"]
[{"$nulls":4},"Castille"]
[{"$nulls":4},"Ferdinand IV"]
[{"$nulls":4},"histoire d'Espagne"]
[{"$nulls":4},"historiographie castillane"]
[{"$nulls":4},"Le Cid"]
[{"$nulls":4},"Marie de Molina"]
[{"$nulls":4},"Moyen Âge"]
[{"$nulls":4},"royauté"]
[{"$nulls":4},"Tierra de Campos"]
[{"$nulls":4},"Castilla"]
[{"$nulls":4},"Edad Media"]
[{"$nulls":4},"Historia de España"]
[{"$nulls":4},"El Cid"]
[{"$nulls":4},"Fernando IV"]
[{"$nulls":4},"Terre de Campos"]
[{"$nulls":4},"caballería"]
[{"$nulls":4},"historiografía castellana"]
[{"$nulls":4},"la realeza"]
[null,null,"Lingua di pubblicazione",null,"Spagnolo"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Sommario/riassunto","Cet ouvrage constitue la première édition d’une version complète de la Chronique de Castille. Peu étudiée et n’ayant fait l’objet que d’éditions partielles, la Chronique de Castille a pourtant connu au Moyen Âge un "]
[{"$nulls":4},"succès et une postérité considérables. Composée à l’aube du XIVe siècle, l’œuvre fut presque aussitôt traduite en galicien et choisie par le comte portugais Pierre de Barcelos comme principale source du Livre des lignages (1343) et de la Chronique de 1344. Elle fut aussi une référence privilégiée pour les historiographes castillans jusqu’au début du XVIe siècle. Un tel succès s’explique sans doute par la large place qu’occupe, dans le texte, le récit de la vie de celui qui fut et demeure le seul héros de la Castille : Rodrigue Diaz de Vivar, dit le Cid. La chronique prend ainsi les traits d’un roman où se déploie tout l’éclat d’une royauté chevaleresque. Élaborée à partir de deux manuscrits de la tradition (le manuscrit Esp. 12 de la Bibliothèque Nationale de France et le manuscrit X-I-11 de la Bibliothèque de l’Escurial), l’édition est précédée d’une présentation de l’œuvre où l’auteur montre que la Chronique de Castille fut sans doute composée à l’initiative de Marie de Molina et qu’elle fut destinée à célébrer l’alliance que la régente avait scellée avec les chevaliers et les bonshommes des villes pour conforter son fils sur le trône.  Ésta es la primera edición de una versión completa de la Crónica de Castilla. Poco estudiada y sólo editada parcialmente, la Crónica de Castilla gozó sin embargo de notable éxito y gran posteridad en la Edad Media. Compuesta a principios del siglo XIV, la obra fue traducida en seguida al gallegoportugués y escogida por el conde portugués Pedro de Barcelos como fuente principal del Libro de los linajes (1343) y de la Crónica de 1344. También fue una referencia privilegiada para los historiógrafos castellanos hasta principios del siglo XVI. Tal éxito se debe sin duda al lugar que ocupa en el texto el relato de la vida del…"]
[null,"2.","Record Nr.",null,"UNINA9910136804003321"]
[null,null,"Autore",null,"Feng Gao"]
[null,null,"Titolo",null,"DNA replication origins in microbial genomes [[electronic resource] /] / edited by Feng Gao"]
[null,null,"Pubbl/distr/stampa",null,"Frontiers Media SA, 2016"]
[{"$nulls":4},"France : , : Frontiers Media SA, , 2016"]
[null,null,"ISBN",null,"9782889197798 (ebook)"]
[null,null,"Descrizione fisica",null,"1 online resource (115 pages) : illustrations, charts"]
[null,null,"Collana",null,"Frontiers Research Topics"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Nota di bibliografia","Includes bibliographical references."]
[null,null,null,"Sommario/riassunto","DNA replication, a central event for cell proliferation, is the basis of biological inheritance. Complete and accurate DNA replication is integral to the maintenance of the genetic integrity of organisms. In all three domains of life, DNA replication begins at replication origins. In bacteria, replication typically initiates from a single replication origin (oriC), which contains several DnaA boxes and the AT-rich DNA unwinding element (DUE). In eukaryotic genomes, replication initiates from significantly more replication origins, activated simultaneously at a specific time. For eukaryotic organisms, replication origins are best characterized in the unicellular eukaryote budding yeast Saccharomyces cerevisiae and the fission yeast Schizosaccharomyces pombe. The budding yeast origins contain an essential sequence element called the ARS (autonomously replicating sequence), while the fission yeast origins consist of AT-rich sequences. Within the archaeal domain, the multiple replication origins have been identified by a predict-and-verify approach in the hyperthermophilic archaeon Sulfolobus. The basic structure of replication origins is conserved among archaea, typically including an AT-rich unwinding region flanked by several short repetitive DNA sequences, known as origin recognition boxes (ORBs). It appears that archaea have a simplified version of the eukaryotic replication apparatus, which has led to considerable interest in the archaeal machinery as a model of that in eukaryotes. The research on replication origins is important not only in providing insights into the structure and function of the replication origins but also in "]
[{"$nulls":4},"understanding the regulatory mechanisms of the initiation step in DNA replication. Therefore, intensive studies have been carried out in the last two decades. The pioneer work to identify bacterial oriCs in silico is the GC-skew analysis. Later, a method of cumulative GC skew without sliding windows was proposed to give better resolution. Meanwhile, an oligomer-skew method was also proposed to predict oriC regions in bacterial genomes. As a unique representation of a DNA sequence, the Z-curve method has been proved to be an accurate and effective approach to predict bacterial and archaeal replication origins. Budding yeast origins have been predicted by Oriscan using similarity to the characterized ones, while the fission yeast origins have been identified initially from AT content calculation. In comparison with the in silico analysis, the experimental methods are time-consuming and labor-intensive, but convincing and reliable. To identify microbial replication origins in vivo or in vitro, a number of experimental methods have been used including construction of replicative oriC plasmids, microarray-based or high-throughput sequencing-based marker frequency analysis, two-dimensional gel electrophoresis analysis and replication initiation point mapping (RIP mapping). The recent genome-wide approaches to identify and characterize replication origin locations have boosted the number of mapped yeast replication origins. In addition, the availability of increasing complete microbial genomes and emerging approaches has created challenges and opportunities for identification of their replication origins in silico, as well as in vivo and in vitro."]