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[null,"1.","Record Nr.",null,"UNINA9910146099803321"]
[null,null,"Titolo",null,"Tumor-associated antigens [[electronic resource] ] : identification, characterization, and clinical applications / / edited by Olivier Gires and Barbara Seliger"]
[null,null,"Pubbl/distr/stampa",null,"Weinheim, : Wiley-VCH, c2009"]
[null,null,"ISBN",null,"1-282-02189-3"]
[{"$nulls":4},"9786612021893"]
[{"$nulls":4},"3-527-62597-6"]
[{"$nulls":4},"3-527-62598-4"]
[null,null,"Descrizione fisica",null,"1 online resource (386 p.)"]
[null,null,"Disciplina",null,"616.994079"]
[null,null,"Soggetti",null,"Tumor antigens"]
[{"$nulls":4},"Tumors - Immunological aspects"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Tumor-Associated Antigens : Identification, Characterization, and Clinical Applications; Contents; List of Contributors; Part One Tumor-associated Antigens (TAAs): Subclasses of TAAs; 1 T Cell Antigens in Cancer; 1.1 Introduction; 1.2 Generation of T-cell Epitopes; 1.2.1 Subclasses of Tumor-associated T-cell Antigens; 1.2.1.1 Unique Tumor Antigens; 1.2.1.2 Cancer Testis Antigens; 1.2.1.3 Differentiation Antigens; 1.2.1.4 Overexpressed Antigens; 1.3 Identification of T-cell Antigens and their Epitopes; 1.3.1 T-cell Antigens for Cancer Immunotherapy - How are Candidates Selected?"]
[{"$nulls":4},"1.4 ConclusionsReferences; 2 Human Tumor Antigens as Targets of Immunosurveillance and Candidates for Cancer Vaccines; 2.1 Introduction; 2.2 Tumor Antigen Classes; 2.2.1 Oncofetal Antigens; 2.2.2 Oncogenes as Tumor Antigens; 2.2.3 Overexpressed Normal Molecules as Tumor Antigens; 2.2.4 Cancer-Testis (CT) Antigens; 2.2.5 Minor Histocompatibility Antigens (mHAgs) as Tumor Antigens; 2.2.6 Human Melanoma Antigens; 2.2.7 Human Glioma Antigens and Immunosurveillance in the CNS; 2.2.8 Heat Shock Proteins, Efficient Carriers of Tumor Antigens"]
[{"$nulls":4},"2.2.9 Dendritic Cells, Efficient Cross-presenters of Tumor Antigens2.2.10 Spontaneous and Vaccine-induced Immunity and the Tumor Microenvironment; 2.3 Summary; References; Part Two Methods to "]
[{"$nulls":4},"Detect TAAs; 3 Humoral Immune Responses against Cancer Antigens: Serological Identification Methods. Part I: SEREX; 3.1 Introduction; 3.2 The SEREX Approach; 3.2.1 Identification of Human Tumor Antigens by SEREX; 3.2.2 Specificity of Human Tumor Antigens; 3.2.2.1 Shared Tumor Antigens; 3.2.2.2 Differentiation Antigens; 3.2.2.3 Antigens Encoded by Mutated Genes; 3.2.2.4 Viral Genes"]
[{"$nulls":4},"3.2.2.5 Overexpressed Genes3.2.2.6 Amplified Genes; 3.2.2.7 Splice Variants of Known Genes; 3.2.2.8 Cancer-related Autoantigens; 3.2.2.9 Non-cancer-related Autoantigens; 3.2.2.10 Products of Underexpressed Genes; 3.2.3 Significance of Antibodies against SEREX Antigens; 3.2.4 Reverse T Cell Immunology; 3.2.5 Functional Significance of Human Tumor Antigens; 3.2.6 The Human Cancer Immunome; 3.2.7 Perspectives for Vaccine Development; 3.3 Conclusions; References; 4 Humoral Immune Responses against Cancer Antigens: Serological Identification Methods. Part II: Proteomex and AMIDA; 4.1 Introduction"]
[{"$nulls":4},"4.1.1 A Humoral Response against Self-antigens: The Notion of Tumor-associated Antigens4.2 Implementation of Serum Antibodies: Serological Screening Technologies; 4.2.1 PROTEOMEX, alias SERPA and SPEARS; 4.2.1.1 PROTEOMEX Technology and its 'Pros' and 'Cons'; 4.2.1.2 Candidate Biomarkers Identified by PROTEOMEX; 4.2.1.3 Implementation of Candidate Biomarkers in the Clinic; 4.2.2 AMIDA; 4.2.2.1 Autologous AMIDA; 4.2.2.2 Allo-AMIDA; 4.2.3 Advantages and Disadvantages of AMIDA; 4.3 AMIDA Antigens and Clinical Application; 4.3.1 Diagnostic TAAs Detected with AMIDA Screening"]
[{"$nulls":4},"4.3.2 Therapeutic Markers"]
[null,null,null,"Sommario/riassunto","The first comprehensive and most recent overview of the topic, this ready reference and handbook reviews current knowledge of TAAs, their subclasses, and pinpoints their application areas in medicine. In addition, it emphasizes target identification procedures, the need for an accurate and thorough analysis of the function of TAAs, and the validation of those in clinical settings. The whole is rounded off with an overview of currently approved therapeutic antibodies.The result is a must-have for biologists and oncologists in science, clinics and industry."]
[null,"2.","Record Nr.",null,"UNINA9910350187203321"]
[null,null,"Titolo",null,"Chinese Poetry and Translation: Rights and Wrongs"]
[null,null,"Pubbl/distr/stampa",null,"Amsterdam, : Amsterdam University Press, 2019"]
[null,null,"ISBN",null,"94-6298-994-X"]
[null,null,"Descrizione fisica",null,"1 online resource (353)"]
[null,null,"Disciplina",null,"895.11009"]
[null,null,"Soggetti",null,"China"]
[{"$nulls":4},"Poetry"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,"Nota di contenuto",null,"Frontmatter -- Table of Contents -- Acknowledgments -- Introduction -- Conventions -- 1 Sitting with Discomfort -- 2 Working with Words -- 3 Translating Great Distances -- 4 Purpose and Form -- 5 Embodiment in the Translation of Chinese Poetry -- 6. Translating Theory -- 7 Narrativity in Lyric Translation -- 8 Sublimating Sorrow -- 9 Mediation Is Our Authenticity -- 10 Ecofeminism avant la Lettre -- 11 Ronald Mar and the Trope of Life -- 12 Ya Xian's Lyrical Montage -- 13 Celan's \"Deathfugue\" in Chinese -- 14 Trauma in Translation -- 15 A Noble Art, and a Tricky Business -- Index"]
[null,null,null,"Sommario/riassunto","Chinese Poetry and Translation: Rights and Wrongs offers fifteen essays on the triptych of poetry + translation + Chinese. The collection has three parts: \"The Translator's Take,\" \"Theoretics,\" and \"Impact.\" The conversation stretches from queer-feminist engagement with China's newest poetry to philosophical and philological reflections on its oldest, and from Tang- and Song-dynasty classical poetry in Western languages to Baudelaire and Celan in Chinese. Translation is taken as an interlingual and intercultural act, and the essays foreground theoretical expositions and the practice of translation in equal but not opposite measure. Poetry has a transforming yet ever-acute relevance in Chinese culture, and this makes it a good entry point for studying Chinese-foreign encounters. Pushing past oppositions that still too often restrict discussions of translation-form versus content, elegance versus accuracy, and \"the original\" versus \"the translated\"-this volume brings a wealth of new thinking to the interrelationships between poetry, translation, and China."]