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[null,"1.","Record Nr.",null,"UNINA9910346753903321"]
[null,null,"Autore",null,"Atsuyoshi Shimada"]
[null,null,"Titolo",null,"Neuroimmune Interface in Health and Diseases"]
[null,null,"Pubbl/distr/stampa",null,"Frontiers Media SA, 2017"]
[null,null,"Descrizione fisica",null,"1 online resource (174 p.)"]
[null,null,"Collana",null,"Frontiers Research Topics"]
[null,null,"Soggetti",null,"Medicine"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Sommario/riassunto","It is now well appreciated that the immune system, in addition to its traditional role in defending the organism against pathogens, communicate in a well-organized fashion with the brain to maintain homeostasis and regulate a set of neural functions. Perturbation in this brain-immune interactions due to inflammatory responses may lead to psychiatric and neurological disorders. Microglia are one of the essential cells involved in the brain-immune interactions. Microglial cells are now not simply regarded as resident tissue macrophages in the brain. These cells are derived from myeloid progenitor cells in the yolk sac in early gestation, travel to the brain parenchyma and interact actively with neurons during the critical period of neurogenesis. Microglia provide a trophic support to developing neurons and take part in the neural wiring through the activity-dependent synapse elimination via direct neuron-microglia interactions. Altered microglial functions including changes in the gene expression due to early life inflammatory events or psychological and environmental stressors can be causally related to neurodevelopmental diseases and mental health disorders. This type of alterations in the neural functions can occur in the absence of infiltration of inflammatory cells in the brain parenchyma or leptomeninges. In this sense, the pathogenetic state underlying a significant part of psychiatric and neurological diseases may be similar to \"para-inflammation\", an intermediate state between homeostatic and classical inflammatory states as defined by Ruslan Medzhitov (Nature 454:428-35, 2008). Therefore, it is important to study how systemic inflammation affects brain health and how local peripheral inflammation induces changes in the brain "]
[{"$nulls":4},"microenvironment. Chronic pain is also induced by disturbance in otherwise well-organized multisystem interplay comprising of reciprocal neural, endocrine and immune interactions. Especially, early-life insults including exposure to immune challenges can alter the neuroanatomical components of nociception, which induces altered pain response later in life. Recently the discrete roles of microglia and blood monocyte-derived macrophages are being defined. The distinction may be further highlighted by disorders in which the brain parenchymal tissue is damaged. Therefore, studies investigating the dynamics of immune cells in traumatic brain injury and neurotropic viral infections including human immunodeficiency virus, etc. as well as neurodegenerative diseases such as amyotrophic lateral sclerosis are promising to clarify the interplay between the central nervous and immune systems. The understanding of the histological architecture providing the infrastructure of such neuro-immune interplay is also essential. This Frontiers research topic brings together fourteen articles and aims to create a platform for researchers in the field of psychoneuroimmunology to share the recent theories, hypotheses and future perspectives regarding open questions on the mechanisms of cell-cell interactions with chemical mediators among the nervous, immune and endocrine systems. We hope that this platform would reveal the relevance of the studies on multisystem interactions to enhance the understanding of the mechanisms underlying a wide variety of neurological and psychiatric disorders."]
[null,"2.","Record Nr.",null,"UNINA9910878050203321"]
[null,null,"Autore",null,"Freymueller Jeffrey T"]
[null,null,"Titolo",null,"Gravity, Positioning and Reference Frames : Proceedings of the IAG Symposia - GGHS2022: Gravity, Geoid, and Height Systems 2022, Austin, TX, United States of America, September 12 – 14, 2022; IAG Commission 4: Positioning and Applications, Potsdam, Germany, September 5 – 8, 2022; REFAG2022: Reference Frames for Applications in Geosciences, Thessaloniki, Greece, October 17 – 20, 2022 / / edited by Jeffrey T. Freymueller, Laura Sánchez"]
[null,null,"Pubbl/distr/stampa",null,"Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2024"]
[null,null,"ISBN",null,"3-031-63855-7"]
[null,null,"Edizione",null,"[1st ed. 2024.]"]
[null,null,"Descrizione fisica",null,"1 online resource (251 pages)"]
[null,null,"Collana",null,"International Association of Geodesy Symposia, , 2197-9359 ; ; 156"]
[null,null,"Disciplina",null,"550"]
[null,null,"Soggetti",null,"Geophysics"]
[{"$nulls":4},"Geotechnical engineering"]
[{"$nulls":4},"Geographic information systems"]
[{"$nulls":4},"Geotechnical Engineering and Applied Earth Sciences"]
[{"$nulls":4},"Geographical Information System"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,"Nota di contenuto",null,"GGHS2022: Gravity Field -- A Comparison of Pointwise and Levelling Assisted Regional Realisations of IHRS With a Case Study Over Sweden -- New Tidal Analysis of Superconducting Gravimeter Records at Metsähovi, Finland -- Development of the National Gravimetric Geoid Model for the Kingdom of Saudi Arabia -- Comparisons of Absolute Gravimeters as a Key Component of the International Terrestrial Gravity Reference Frame (ITGRF) Shown on the Example of the WET-CAG2021 at Wettzell, Germany -- Newly Acquired Gravity Data in Support of the GeoNetGNSS CORS Network in Northern Greece -- Strapdown Airborne Gravimetry Based on Aircrafts and UAVs: Postprocessing Algorithms and New Results -- Estimation of Temporal Variations in the Earth’s Gravity Field Using Novel Optical Clocks Onboard of Low Earth Orbiters -- Hybrid Geoid Modeling for the Kingdom of Saudi Arabia -- IAG Commission 4: Positioning and Applications -- Almost-Instantaneous PPP-RTK Without Atmospheric Corrections -- Multi-GNSS 1 Tomography: Case Study of the July 2021 Flood in Germany -- Quantum Diamond Magnetometry for Navigation in GNSS Denied "]
[{"$nulls":4},"Environments -- Feasibility of CSAC-Assisted GNSS Receiver Fingerprinting -- On the Impact of GNSS Receiver Settings on the Estimation of Codephase Center Corrections -- Quality Control Methods for Climate Applications of Geodetic Tropospheric Parameters -- REFAG2022: Reference Frames -- Impact of Coordinate- and Tropospheric Ties on the Rigorous Combination of GNSS and VLBI -- How Do Atmospheric Tidal Loading Displacements Vary Temporally as well as Across Different Weather Models? -- Alternative Strategies for the Optimal Combination of GNSS and Classical Geodetic Networks: A Case-study in Greece -- A Concept of Precise VLBI/GNSS Ties with Micro-VLBI -- Status of the SIRGAS Reference Frame: Recent Developments and New Challenges -- A Review of Space Geodetic Technique Seasonal Displacements Based on ITRF2020 Results -- Validation of Reference Frame Consistency of GNSS Service Products -- Intra-Technique Combination of VLBI Intensives and Rapid Data to Improve the Temporal Regularity and Continuity of the UT1-UTC Series -- Automatic Determination of the SLR Reference Point at Côte d’Azur Multi-technique Geodetic Observatory -- The K-band (24 GHz) Celestial Reference Frame Determined from Very Long Baseline Interferometry Sessions Conducted over the Past 20 Years -- VGOS VLBI Intensives Between macgo12m and wettz13s for the Rapid Determination of UT1-UTC -- Correcting Non-tidal Surface Loading in GNSS repro3 and Comparison with ITRF2020 -- Upgrading the Metsähovi Geodetic Research Station -- Assessing the Potential of VLBI Transmitters on Next Generation GNSS Satellites for Geodetic Products -- Potential of Lunar Laser Ranging for the Determination of Earth Orientation Parameters."]
[null,null,null,"Sommario/riassunto","This open access volume contains a selection of papers presented at three different IAG Symposia held in 2022: GGHS2022 – Gravity, Geoid, and Height Systems 2022, Austin, TX, United States of America, September 12 – 14, 2022; IAG Commission 4 – Positioning and Applications, Potsdam, Germany, September 5 – 8, 2022; and REFAG2022 – Reference Frames for Applications in Geosciences, Thessaloniki, Greece, October 17 – 20, 2022. Two of these three conferences were planned for 2020 or 2021, but had to be postponed due to the COVID19 pandemic. They therefore became an important opportunity for the global geodesy community to rebuild professional networks and to resume face-to-face interaction. Scientists from around the world were delighted to once again gather together to present their research progress and findings, and discuss scientific issues."]