{"text_format":"2","workbook":"xls","n_sheets":1,"sheets":["report2"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":1,"defined_names":2,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"report2","index":0,"n_rows":44,"n_cols":5,"rows_kept":44,"cut":false,"hidden":false,"merged":[[0,2,0,3],[0,4,0,5],[1,2,1,3],[1,4,1,5],[2,2,2,3],[3,2,3,3],[5,2,5,3],[6,2,6,3],[7,2,7,3],[8,2,8,3],[9,2,9,3],[20,2,20,3],[21,2,21,3],[23,2,23,3],[26,2,26,3],[26,4,26,5],[27,2,27,3],[27,4,27,5],[28,2,28,3],[28,4,28,5],[29,2,29,3],[31,2,31,3],[32,2,32,3],[33,2,33,3],[34,2,34,3],[35,2,35,3],[37,2,37,3],[38,2,38,3],[41,2,41,3]],"flags":["formulas_cached_only"]}
[null,"1.","Record Nr.",null,"UNINA9910337929603321"]
[null,null,"Titolo",null,"Advances in Computational Toxicology : Methodologies and Applications in Regulatory Science / / edited by Huixiao Hong"]
[null,null,"Pubbl/distr/stampa",null,"Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019"]
[null,null,"ISBN",null,"3-030-16443-8"]
[{"$nulls":4},"9783030164430"]
[null,null,"Edizione",null,"[1st ed. 2019.]"]
[null,null,"Descrizione fisica",null,"1 online resource (416 pages)"]
[null,null,"Collana",null,"Challenges and Advances in Computational Chemistry and Physics, , 2542-4491 ; ; 30"]
[null,null,"Disciplina",null,"025.066159"]
[null,null,"Soggetti",null,"Chemoinformatics"]
[{"$nulls":4},"Pharmacology"]
[{"$nulls":4},"Bioinformatics "]
[{"$nulls":4},"Computational biology "]
[{"$nulls":4},"Chemistry, Physical and theoretical"]
[{"$nulls":4},"Bioinformatics"]
[{"$nulls":4},"Computer Applications in Chemistry"]
[{"$nulls":4},"Pharmacology/Toxicology"]
[{"$nulls":4},"Computer Appl. in Life Sciences"]
[{"$nulls":4},"Theoretical and Computational Chemistry"]
[{"$nulls":4},"Computational Biology/Bioinformatics"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,"Nota di contenuto",null,"Computational Toxicology Promotes Regulatory Science -- Tasks, Major Challenges and Emerging Modelling Methods for Computational Toxicology -- Xenobiotic Metabolism by Cytochrome P450s: Insights Gained from Molecular Simulations -- Applications of Molecular Modeling to Probe the Mechanism of Endocrine Disruptor Action -- Mixture Toxicity -- Towards reproducible in silico practice via OpenTox -- Combining Machine Learning and Multilayer Networks for Toxicity Prediction -- Matrix and tensor factorization for toxicity modelling -- Network-based In Silico Assessment of Drug Cardiotoxicity -- Mode-of-action-guided chemical toxicity prediction: A novel in silico approach for predictive toxicology -- Machine learning methods for toxicity analysis -- Predictive modeling of Tox21 data -- The NTP "]
[{"$nulls":4},"DrugMatrix Toxicogenomics Database and Analysis Tool -- Applications of Computational Toxicology for Risk Assessment of Food Ingredients and Indirect Food Additives -- In silico prediction of the point of departure (POD) with high throughput data -- The application of topic modeling on drug safety signal detection and analysis -- Molecular dynamics simulations and applications in computational toxicology -- Computational modeling for prediction of drug-induced liver injury in humans -- Genomics in vitro to in vivo extrapolation (GIVIVE) for drug safety evaluation."]
[null,null,null,"Sommario/riassunto","This book provides a comprehensive review of both traditional and cutting-edge methodologies that are currently used in computational toxicology and specifically features its application in regulatory decision making. The authors from various government agencies such as FDA, NCATS and NIEHS industry, and academic institutes share their real-world experience and discuss most current practices in computational toxicology and potential applications in regulatory science. Among the topics covered are molecular modeling and molecular dynamics simulations, machine learning methods for toxicity analysis, network-based approaches for the assessment of drug toxicity and toxicogenomic analyses. Offering a valuable reference guide to computational toxicology and potential applications in regulatory science, this book will appeal to chemists, toxicologists, drug discovery and development researchers as well as to regulatory scientists, government reviewers and graduate students interested in this field."]
[null,"2.","Record Nr.",null,"UNINA9910814041103321"]
[null,null,"Autore",null,"Porete Marguerite <approximately 1250-1310.>"]
[null,null,"Titolo",null,"A companion to Marguerite Porete and the mirror of simple souls / / edited by Wendy R. Terry, Robert Stauffer"]
[null,null,"Pubbl/distr/stampa",null,"Leiden, Netherlands ; ; Boston, [Massachusetts] : , : Brill, , 2017"]
[{"$nulls":4},"©2017"]
[null,null,"ISBN",null,"90-04-33856-X"]
[null,null,"Descrizione fisica",null,"1 online resource (383 pages) : illustrations"]
[null,null,"Collana",null,"Brill's Companions to the Christian Tradition, , 1871-6377 ; ; Volume 77"]
[null,null,"Disciplina",null,"248.22"]
[null,null,"Soggetti",null,"Contemplation"]
[{"$nulls":4},"Spiritual life - Christianity"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Introduction / Wendy R. Terry -- Marguerite Porete and the Writing of the Mirror -- Debating the Historical Marguerite Porete* / Sean L. Field -- Marguerite’s Mystical Annihilation / Joanne Maguire Robinson -- A Review of Possible Theological Sources for Marguerite Porete’s Mirror / Wendy R. Terry -- Literary Sources of The Mirror of Simple Souls / Zan Kocher -- “Ce livre monstrera a tous vraye lumiere de verité.” The Role of The Mirror of Simple Souls as a Book* / Imke de Gier -- Translations and Transmission of the Mirror -- The Tradition of The Mirror of Simple Souls in the Fifteenth Century: From Marguerite Porete (†1310) to Marguerite of Navarre (†1549) / Geneviève Hasenohr, translated by Zan Kocher -- The Latin Manuscripts of The Mirror of Simple Souls* / Justine L. Trombley -- The Italian Version of the Mirror: Manuscripts, Diffusion and Communities in the 14–15th Century* / Dávid Falvay -- Further Thoughts on m.n.’s Middle English Translation of Marguerite’s Mirouer des simples âmes anienties / Marleen Cré -- Possibilities for the Identity of the English Translator of The Mirror of Simple Souls / Robert Stauffer -- Modern Scholarship: Looking Forward, Looking Back -- Critical Approaches to Marguerite Porete / Elizabeth Scarborough -- Mirrors on the Wall: Which One is Fairest of Them All? / Jonathan H. Juilfs."]
[null,null,null,"Sommario/riassunto","Even with growing popularity in the United States, there existed no English-language scholarly introduction to Marguerite Porete or her sole-surviving work Mirror of Simple Souls until now. The study of Marguerite and her work touches on so many disciplines – from "]
[{"$nulls":4},"religious and secular histories to theological and literary readings of her book – that the scholarship had often been lost in the divides between the disciplines. Our contributors are chosen from both sides of the Atlantic and from an array of disciplines in order to bridge this geographical and linguistic divide. The interdisciplinary nature of the interest in Marguerite and the Mirror and the implications her book has on medieval scholarship make a collection such as this companion ideal. Contributors are Marleen Cré, Imke De Gier, Dávid Falvay, Sean Field, Geneviève Hasenohr (with Zan Kocher), Jonathan Juilfs, Zan Kocher, Joanne Robinson, Elizabeth Scarborough, Robert Stauffer, Wendy R. Terry, and Justine Trombley."]