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[null,"1.","Record Nr.",null,"UNINA9910300208803321"]
[null,null,"Titolo",null,"Raynaud’s Phenomenon : A Guide to Pathogenesis and Treatment / / edited by Fredrick M. Wigley, Ariane L. Herrick, Nicholas A. Flavahan"]
[null,null,"Pubbl/distr/stampa",null,"New York, NY : , : Springer New York : , : Imprint : Springer, , 2015"]
[null,null,"ISBN",null,"1-4939-1526-6"]
[null,null,"Edizione",null,"[1st ed. 2015.]"]
[null,null,"Descrizione fisica",null,"1 online resource (400 p.)"]
[null,null,"Disciplina",null,"610"]
[{"$nulls":4},"616"]
[{"$nulls":4},"616.5"]
[{"$nulls":4},"616723"]
[null,null,"Soggetti",null,"Rheumatology"]
[{"$nulls":4},"Internal medicine"]
[{"$nulls":4},"Dermatology"]
[{"$nulls":4},"Internal Medicine"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references at the end of each chapters and index."]
[null,null,"Nota di contenuto",null,"Historical perspective of Raynaud's phenomenon -- definition, nomenclature and diagnostic criteria -- Epidemiology of Raynaud’s Phenomenon -- Thermoregulation: The Normal Structure and Function of the Cutaneous Vascular System -- Pathophysiological Regulation of the Cutaneous Vascular System in Raynaud’s Phenomenon -- Primary Raynaud’s Phenomenon -- Raynaud Phenomenon In The Pediatric Age.-Secondary Raynaud’s phenomenon -- Traumatic Vasospastic Disease -- Other Secondary Causes -- Raynaud’s Mimics -- Nailfold Capillaries.-Non-Invasive methods of assessing Raynaud’s phenomenon -- Angiography -- Autoantibodies in Raynaud’s Phenomenon -- Systemic Vasospasm -- Clinical Outcome Measures in Raynaud’s Phenomenon -- Design and reporting of randomised controlled trials for Raynaud’s phenomenon -- Non-drug Approaches to Treating Raynaud’s Phenomenon -- Drug Treatment of Raynaud’s Phenomenon -- Management of digital ischemia -- Surgical Management -- Practical Approaches to Treatment: Case Studies."]
[null,null,null,"Sommario/riassunto","Raynaud’s Phenomenon: A Guide to Pathogenesis and Treatment comprehensively reviews the understanding of a disorder that continues to challenge primary care clinicians and specialists alike.   In "]
[{"$nulls":4},"the last decade, there have been important advances not only in understanding the pathophysiology of Raynaud’s Phenomenon (RP), but also in developing diagnostic methods and effective drug and non-drug therapies.  Thoroughly discussing the various manifestations of RP, including childhood RP, RP secondary to connective tissue disease, and a variety of other associated disorders that include vascular perturbation that mimics RP, this title provides a wealth of new information available on normal and abnormal thermoregulation and helps physicians identify the best therapeutic approaches to treating RP.  The work offers differential diagnosis options, reviews potential causes -- such as autoimmune disease, industrial trauma, drugs, and metabolic causes --  and provides clear recommendations for therapy.  Engaging readers with case vignettes and a plethora of visual aids, Raynaud’s Phenomenon: A Guide to Pathogenesis and Treatment is a state-of-the-art, authoritative reference and invaluable contribution to the literature that will be of interest to physicians, patients, and individuals dealing with these disease processes."]