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[null,"1.","Record Nr.",null,"UNINA9910300191703321"]
[null,null,"Titolo",null,"Pre-Analytics of Pathological Specimens in Oncology / / edited by Manfred Dietel, Christian Wittekind, Gianni Bussolati, Moritz Winterfeld"]
[null,null,"Pubbl/distr/stampa",null,"Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015"]
[null,null,"ISBN",null,"3-319-13957-6"]
[null,null,"Edizione",null,"[1st ed. 2015.]"]
[null,null,"Descrizione fisica",null,"1 online resource (134 p.)"]
[null,null,"Collana",null,"Recent Results in Cancer Research, , 2197-6767 ; ; 199"]
[null,null,"Disciplina",null,"610"]
[{"$nulls":4},"610724"]
[{"$nulls":4},"616.07"]
[{"$nulls":4},"616994"]
[{"$nulls":4},"617"]
[null,null,"Soggetti",null,"Oncology"]
[{"$nulls":4},"Pathology"]
[{"$nulls":4},"Surgery"]
[{"$nulls":4},"Medicine - Research"]
[{"$nulls":4},"Biology - Research"]
[{"$nulls":4},"Biomedical Research"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,"Nota di contenuto",null,"What Is Pre-Analytics in Surgical Pathology?  -- Histologic Validation of Vacuum Sealed Formalin -- Free Tissue Preservation and Transport System  -- Pre-Analytics and Molecular Pathology -- Experiences in Vacuum Preparation of Routine Specimens -- Tissue Heterogeneity as a Pre-Analytical Source of Variability -- Vacuum Fixation of Breast Specimens Before Grossing -- How Do Short Fixation and Rapid Microwave Processing Affect Her2 Testing? -- Current Projects in Pre-Analytics – Where to Go? -- Nucleic Acid Extraction from FFPE Tissue as Critical Preanalytic Step for NGS Applications -- Experiences With Pre-Analytics of Lung Specimen -- Experiences With Pre-Analytics of GI-Specimen -- Bone Marrow Work-Up -- Two-Temperature Fixation Preserves Activation Status with High Efficiency -- Towards the Lean Lab. The Industry Challenge.  ."]
[null,null,null,"Sommario/riassunto","This book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in "]
[{"$nulls":4},"particular potential ways to improve the situation whereby methods employed in the pre-analytical phase – the period from surgical removal of tissue to the start of pathological processing – have remained essentially unchanged for decades with only modest standardization. It is examined how the pre-analytical period can be optimized, resulting not only in an increase in diagnostic quality but also in a reduction in processing time and costs. Among the key topics examined are the so-called cold ischemia time between tissue removal and fixation, the potential superiority of vacuum-based preservation over immediate formalin fixation, two-temperature fixation, molecular analysis methods, and the pre-analytics of specimens from particular tissues. Readers will find this book to be an important update that reveals the full importance of the pre-analytical phase for quality of pathological work-up."]