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[null,"1.","Record Nr.",null,"UNINA9910139054303321"]
[null,null,"Titolo",null,"Molecular basis of oxidative stress [[electronic resource] ] : chemistry, mechanisms, and disease pathogenesis / / edited by Frederick A. Villamena"]
[null,null,"Pubbl/distr/stampa",null,"Hoboken, N.J., : Wiley, c2013"]
[null,null,"ISBN",null,"1-118-35587-3"]
[{"$nulls":4},"1-118-35588-1"]
[{"$nulls":4},"1-118-35586-5"]
[null,null,"Descrizione fisica",null,"1 online resource (448 p.)"]
[null,null,"Disciplina",null,"571.9/453"]
[null,null,"Soggetti",null,"Oxidative stress"]
[{"$nulls":4},"Oxidation"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references at the end of each chapters and index."]
[null,null,"Nota di contenuto",null,"Cover; Title page; Copyright page; Contents; Preface; About the Contributors; Contributors; 1: Chemistry of Reactive Species; 1.1 Redox Chemistry; 1.2 Classification of Reactive Species; 1.2.1 Type of Orbitals; 1.2.2 Stability of Radicals; 1.2.3 ROS; 1.2.4 Reactive Nitrogen Species; 1.2.5 Reactive Sulfur and Chlorine Species; 1.3 Reactivity; 1.3.1 Thermodynamic Considerations; 1.3.2 Kinetic Considerations; 1.4 Origins of Reactive Species; 1.4.1 Biological Sources; 1.4.2 Nonbiochemical Sources; 1.5 Methods of Detection; 1.5.1 In Vitro; 1.5.2 In Vivo; References"]
[{"$nulls":4},"2: Lipid Peroxidation and NitrationOverview; 2.1 Peroxidation of PUFAs; 2.1.1 Hydroperoxy Fatty Acid Isomers (HpETEs and HpODEs); 2.1.2 Hydroxy Fatty Acids (HETEs and HODEs); 2.1.3 Isoleukotrienes; 2.1.4 Epoxy Alcohols; 2.2 Cyclic Endoperoxides and Their Products; 2.2.1 Isoprostanes; 2.2.2 Diepoxide Pathway Products; 2.2.3 Serial Cyclic Endoperoxides; 2.3 Fragmented Products of Lipid Peroxidation; 2.3.1 Short-Chain Alkanes, Aldehydes, and Acids; 2.3.2 Oxidatively Fragmented Phospholipids; 2.3.3 PAF Acetylhydrolase; 2.3.4 Hydroxyalkenals; 2.3.5 Malondialdehyde; 2.3.6 Acrolein"]
[{"$nulls":4},"2.4 Epoxy Fatty Acids2.5 Lipid Nitrosylation; 2.5.1 Formation of Reactive Nitrogen Species; 2.5.2 Lipid Nitration Reactions; 2.5.3 Detection of Lipid Nitration In Vivo; 2.5.4 Bioactivities of Nitrated Lipids; Summary; References; 3: Protein Posttranslational Modification; "]
[{"$nulls":4},"Overview; 3.1 Oxidative Stress-Related PTMs: Oxidation Reactions; 3.1.1 Cysteine; 3.1.2 Methionine; 3.1.3 Oxidation of Aromatic Amino Acids; 3.1.4 Oxidation of Aliphatic Amino Acids; 3.2 Amino Acid Modification by Oxidation-Produced Electrophiles; 3.2.1 Electrophiles Formed by Oxidative Stress"]
[{"$nulls":4},"4.3.3 Novel Types of Ribose and Guanine Oxidative Lesions and Future OutlookFuture Outlook of DNA Oxidative Lesions; References; 5: Downregulation of Antioxidants and Phase 2 Proteins; Overview; 5.1 Definitions of Antioxidants and Phase 2 Proteins; 5.1.1 Antioxidants; 5.1.2 Phase 2 Proteins; 5.2 Roles in Oxidative Stress; 5.2.1 Superoxide Dismutase; 5.2.2 Catalase; 5.2.3 GSH and GSH-Related Enzymes; 5.2.4 NAD(P)H:Quinone Oxidoreductase; 5.2.5 Heme Oxygenase; 5.2.6 Ferritin; 5.2.7 UDP-Glucuronosyltransferase; 5.3 Molecular Regulation; 5.3.1 General Consideration; 5.3.2 Nrf2 Signaling"]
[{"$nulls":4},"5.3.3 Other Regulators"]
[null,null,null,"Sommario/riassunto","Sets the stage for the development of better diagnostic techniques and therapeutics  Featuring contributions from an international team of leading clinicians and biomedical researchers, Molecular Basis of Oxidative Stress reviews the molecular and chemical bases of oxidative stress, describing how oxidative stress can lead to the development of cancer and cardiovascular and neurodegenerative diseases. Moreover, it explains the potential role of free radicals in both the diagnosis and the development of therapeutics to treat disease. Molecular Basis of Oxidative Stres"]
[null,"2.","Record Nr.",null,"UNINA9910299959203321"]
[null,null,"Autore",null,"Kachroo Pushkin"]
[null,null,"Titolo",null,"Feedback Control Theory for Dynamic Traffic Assignment / / by Pushkin Kachroo, Kaan M.A. Özbay"]
[null,null,"Pubbl/distr/stampa",null,"Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018"]
[null,null,"ISBN",null,"3-319-69231-3"]
[null,null,"Edizione",null,"[2nd ed. 2018.]"]
[null,null,"Descrizione fisica",null,"1 online resource (XXXI, 272 p.)"]
[null,null,"Collana",null,"Advances in Industrial Control, , 1430-9491"]
[null,null,"Disciplina",null,"629.8"]
[null,null,"Soggetti",null,"Automatic control"]
[{"$nulls":4},"Regional planning"]
[{"$nulls":4},"City planning"]
[{"$nulls":4},"Civil engineering"]
[{"$nulls":4},"Control and Systems Theory"]
[{"$nulls":4},"Landscape/Regional and Urban Planning"]
[{"$nulls":4},"Civil Engineering"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,"Nota di contenuto",null,"Introduction -- Trafﬁc Assignment: A Survey of Mathematical Models and Techniques -- Trafﬁc Flow Theory -- Modeling and Problem Formulation -- Dynamic Routing Problem in Distributed Parameter Setting -- Dynamic Routing Problem in Distributed Parameter Setting using Semigroup Theory -- Fuzzy Feedback Control for Dynamic Routing Problem -- Feedback Control for Dynamic Trafﬁc Routing in Lumped Parameter Setting -- Feedback Control for Network Level Dynamic Trafﬁc Routing -- Feedback Routing via Congestion Pricing. ."]
[null,null,null,"Sommario/riassunto","This book develops a methodology for designing feedback control laws for dynamic traffic assignment (DTA) exploiting the introduction of new sensing and information-dissemination technologies to facilitate the introduction of real-time traffic management in intelligent transportation systems. Three methods of modeling the traffic system are discussed: partial differential equations representing a distributed-parameter setting; continuous-time ordinary differential equations (ODEs) representing a continuous-time lumped-parameter setting; and discreet-time ODEs representing a discrete-time lumped-parameter setting. Feedback control formulations for reaching road-user-equilibrium are presented for each setting and advantages and "]
[{"$nulls":4},"disadvantage of using each are addressed. The closed-loop methods described are proposed expressly to avoid the counter-productive shifting of bottlenecks from one route to another because of driver over-reaction to routing information. The second edition of Feedback Control Theory for Dynamic Traffic Assignment has been thoroughly updated with completely new chapters: a review of the DTA problem and emphasizing real-time-feedback-based problems; an up-to-date presentation of pertinent traffic-flow theory; and a treatment of the mathematical solution to the traffic dynamics. Techinques accounting for the importance of entropy are further new inclusions at various points in the text. Researchers working in traffic control will find the theoretical material presented a sound basis for further research; the continual reference to applications will help professionals working in highway administration and engineering with the increasingly important task of maintaining and smoothing traffic flow; the extensive use of end-of-chapter exercises will help the graduate student and those new to the field to extend their knowledge. Advances in Industrial Control reports and encourages the transfer of technology in control engineering. The rapid development of control technology has an impact on all areas of the control discipline. The series offers an opportunity for researchers to present an extended exposition of new work in all aspects of industrial control."]