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[null,"1.","Record Nr.",null,"UNINA9910298623603321"]
[null,null,"Autore",null,"Yang Yangyang"]
[null,null,"Titolo",null,"Artificially Controllable Nanodevices Constructed by DNA Origami Technology : Photofunctionalization and Single-Molecule Analysis / / by Yangyang Yang"]
[null,null,"Pubbl/distr/stampa",null,"Tokyo : , : Springer Japan : , : Imprint : Springer, , 2015"]
[null,null,"ISBN",null,"4-431-55769-5"]
[null,null,"Edizione",null,"[1st ed. 2015.]"]
[null,null,"Descrizione fisica",null,"1 online resource (82 p.)"]
[null,null,"Collana",null,"Springer Theses, Recognizing Outstanding Ph.D. Research, , 2190-5053"]
[null,null,"Disciplina",null,"540"]
[null,null,"Soggetti",null,"Nanochemistry"]
[{"$nulls":4},"Nanotechnology"]
[{"$nulls":4},"Microscopy"]
[{"$nulls":4},"Spectrum analysis"]
[{"$nulls":4},"Biological Microscopy"]
[{"$nulls":4},"Spectroscopy and Microscopy"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references."]
[null,null,"Nota di contenuto",null,"Introduction -- Direct observation of single hybridization and dissociation of photoresponsive oligonucleotides in the designed DNA nanostructure -- Direct observation of logic-gated dual-switching behaviors inducing the state transition in a DNA nanostructure -- Multi-directionally photo-controllable DNA nanostructure assembling reversibly in programmed patterns -- Arrangement of gold nanoparticles onto a slit-type DNA nanostructure in various patterns."]
[null,null,null,"Sommario/riassunto","In this book, the author deals mainly with two topics: (1) single-molecule visualization of switching behaviors in the DNA nanoframe system utilizing different kinds of molecular switches through the use of high-speed atomic force microscope (AFM); (2) construction of photocontrollable DNA nanostructures in programmed patterns and direct visualization of the dynamic assembling process. Here, high-speed AFM was employed to observe the dynamic movements of single molecules. Compared to a traditional single-molecule analysis method, such as fluorescence spectroscopy or electron microscopy, high-speed AFM makes possible the real-time observation of molecule behaviors. DNA nanostructures were designed and assembled as scaffolds to incorporate interested biomolecules. The observations were carried out "]
[{"$nulls":4},"under robust conditions without complicated pretreatment. Moreover, the photoresponsive molecules were successfully assembled into around 100 nm-sized DNA nanostructures. The assembly/disassembly of nanostructures can be regulated reversibly by photoirradiation. This book explains how DNA origami has gradually become a useful tool for the investigation of biochemical interactions in defined nanospace. It also shows the possibility of DNA nanostructures acting as nanodevices for application in biological systems, serving as a good introduction to basic DNA nanotechnology."]