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[null,"1.","Record Nr.",null,"UNINA9910298296703321"]
[null,null,"Titolo",null,"Nutrition, Exercise and Epigenetics: Ageing Interventions / / edited by Byung Pal Yu"]
[null,null,"Pubbl/distr/stampa",null,"Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015"]
[null,null,"ISBN",null,"9783319148304"]
[{"$nulls":4},"3-319-14829-X"]
[null,null,"Edizione",null,"[1st ed. 2015.]"]
[null,null,"Descrizione fisica",null,"1 online resource (279 p.)"]
[null,null,"Collana",null,"Healthy Ageing and Longevity, , 2199-9015 ; ; 2"]
[null,null,"Disciplina",null,"305.26"]
[{"$nulls":4},"571.6"]
[{"$nulls":4},"572.6"]
[{"$nulls":4},"610"]
[{"$nulls":4},"612.67"]
[{"$nulls":4},"616.2"]
[{"$nulls":4},"618.97"]
[null,null,"Soggetti",null,"Medicine - Research"]
[{"$nulls":4},"Biology - Research"]
[{"$nulls":4},"Geriatrics"]
[{"$nulls":4},"Cytology"]
[{"$nulls":4},"Nutrition"]
[{"$nulls":4},"Aging"]
[{"$nulls":4},"Post-translational modification"]
[{"$nulls":4},"Biomedical Research"]
[{"$nulls":4},"Cell Biology"]
[{"$nulls":4},"Ageing"]
[{"$nulls":4},"Post-translational Modifications"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references at the end of each chapters and index."]
[null,null,"Nota di contenuto",null,"Preface -- Epigenetics and Nutrition -- Calorie restriction as a potent epigenetic modifier -- Anti-inflammatory action of calorie restriction for aging intervention -- Hormonal influence and modulation on aging -- Epigenetic modification by exercise -- Physiological bases and underlying mechanisms of exercise -- Sarcopenia and its intervention "]
[{"$nulls":4},"-- Nutritional impacts on osteopenia and osteoporosis -- Nutritional interventions for cardiac aging and age-related cardiovascular diseases -- Nutritional influence on aging brain -- Mechanistic bases of calorie restriction mimetics -- Lessons learned from calorie restricted non-human primate research."]
[null,null,null,"Sommario/riassunto","This book focuses on the three most important aspects of ageing research: nutrition, physical exercise and epigenetics. The contributors discuss ways that age-related epigenetic imprints such as DNA methylation and histone acetylation are modified by these two interventions. The emphasis on epigenetics helps to illuminate the underlying mechanisms of anti-ageing interventions, as ageing and disease are predominately epigenetic phenomena. Among the highlights are chapter-length discussion of such topics as:  how anti-inflammatory action of calorie restriction underlies the retardation of ageing and age-related diseases (Chapter 3); epigenetic modification of gene expression by exercise (Chapter 5); the role of functional foods and their bioactive components in bone health (Chapter 8); and an account of the first decade of a study of calorie restriction in nonhuman primates, conducted by the National Institute on Ageing.  ."]