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[null,"1.","Record Nr.",null,"UNINA9910785884703321"]
[null,null,"Titolo",null,"The cinema of Latin America / / edited by Alberto Elena & Marina Díaz López"]
[null,null,"Pubbl/distr/stampa",null,"London ; ; New York, : Wallflower, 2003"]
[null,null,"ISBN",null,"0-231-50194-3"]
[null,null,"Descrizione fisica",null,"1 online resource (281 p.)"]
[null,null,"Collana",null,"24 frames"]
[null,null,"Disciplina",null,"791.43098"]
[null,null,"Soggetti",null,"Motion pictures - Latin America - History"]
[{"$nulls":4},"Motion pictures - History"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references, filmography, and index."]
[null,null,"Nota di contenuto",null,"Contents; Notes on Contributors; Preface; Introduction; Limite/Limit; Alla En El Rancho Grande / Over There on the Big Ranch; Besos Brujos / Enchanting Kisses; Maria Candelaria; Los Olvidados / The Young and the Damned; O Cangaceiro; Rio, 40 Graus / Rio, 40 Degrees; La Casa Del Angel / The House of the Angel; Deus O Diabo Na Terra Do Sol / Black God, White Devil; Memorias Del Subdesarrollo / Memories of Underdevelopment; Lucia; La Hora De Los Hornos / The Hour of the Furnaces; Reed: Mexico Insurgente / Reed: Insurgent Mexico; De Cierta Manera / One Way or Another"]
[{"$nulls":4},"La Batalla De Chile / The Battle of ChileBye Bye Brasil / Bye Bye Brazil; Tiempo De Revancha / Time of Revenge; La Historia Oficial / The Official Story; La Boca Del Lobo / The Lion's Den; La Nancion Clandestina / The Clandestine Nation; Principio y Fin / Beginning and End; Terra Estrangeira / Foreign Land; Amores Perros / Love's a Bitch; La Cienaga / The Swamp; Filmography; Bibliography; Index"]
[null,null,null,"Sommario/riassunto","The Cinema of Latin America is the first volume in the new 24 Frames series of studies of national and regional cinema. In taking an explicitly text-centered approach, the books in this series offer a unique way of considering the particular concerns, styles and modes of representation of numerous national cinemas around the world. This volume focuses on the vibrant practices that make up Latin American cinema, a historically important regional cinema and one that is increasingly returning to popular and academic appreciation. Through 24 individual concise and insightful essays tha"]
[null,"2.","Record Nr.",null,"UNINA9910261145003321"]
[null,null,"Autore",null,"Rosalinda Guevara-Guzman"]
[null,null,"Titolo",null,"Neurodegeneration: From Genetics to Molecules"]
[null,null,"Pubbl/distr/stampa",null,"Frontiers Media SA, 2016"]
[null,null,"Descrizione fisica",null,"1 online resource (264 p.)"]
[null,null,"Collana",null,"Frontiers Research Topics"]
[null,null,"Soggetti",null,"Neurosciences"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Sommario/riassunto","Chronic degenerative diseases are one of the major public health problems, particularly those affecting the nervous system. They are characterized by the degeneration of specific cell populations that include several pathologies which contribute significantly to morbidity and mortality in the elderly population. Therefore, in recent years, the study of neuroscience has gained significant importance. Most of these neurodegenerative disorders are the result of a complex interaction between genetic and environmental factors that generate progression and can even determine its severity. The presence of mutations in genes as LRRK2, SNCA, PARK7, PARK2 or PINK1 is associated with Parkinson's disease. Mutations in genes such as APP, PS1 and PS2 are associated with familial Alzheimer's disease; while HTT gene mutations are the cause of Huntington's disease. In most cases, this condition is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder. It is known that these mutations can also alter the proteins function; however, it has not yet been possible to fully understand how some genetic changes cause the disease or influence the risk of developing these disorders. Most symptoms seen in these conditions occurs when specific nerve cells are damaged or die generating a loss in brain communication. Also many of these mutations generate aggregation of intracellular or extracellular proteins affecting cell function and eventually causing neuronal death. It is unclear whether the presence of these aggregates play an important role in nerve cell death during the development of neurodegenerative diseases, or if they are simply part of the response of cells to the disease. Other mutations affect the "]
[{"$nulls":4},"mitochondrial function generating alterations in energy production and promoting the formation of unstable molecules such as free radicals. Under normal conditions, the harmful effects caused by free radicals, are offset within the cell. However, in pathological conditions, the presence of mutations can alter this process by allowing the accumulation of radicals and damaging or killing cells. On the other hand, we also know that these diseases may not have a direct genetic component, thus, the study of sporadic type neurodegenerative diseases is much more complex. Histopathological lesions as well as the cellular and molecular alterations are generally indistinguishable from familial cases. For this reason, it is important to understand the genetic and molecular mechanisms associated with this type of pathologies. In this sense, this issue aims to understand the molecular processes that occur in the brain, and how these are influenced by the environment, genetics and behavior."]